Posted by admin on Sep 1, 2011 in |
Amaranthus tricolor Linn. belonging to the family Amaranthaceae is well known for curing a variety of ailments such as cough, throat infections, toothache, eczema, piles, diarrhea, gonorrhea, leucorrhoea and impotence. The present study deals with the pharmacognostic evaluation including examinations of morphological and microscopic characters, ash values, powder analysis, extractive values, moisture content and fluorescence analysis. Preliminary phytochemical screening was also carried out. Transverse section of the root showed the presence of cork cells, cortex, fibers, xylem and phloem. Total ash, acid insoluble ash, water soluble ash, ethanol soluble extractive and water soluble extractive were 12.8%, 6.89%, 5.0%, 7.6% and 20.0% w/w respectively. Phytochemical screening showed the presence of alkaloids, flavonoids, glycosides, tannins, proteins and amino acids. The study contributes to the development of standardization parameters of the plant which helps in the botanical identification of Amaranthus tricolor...
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Posted by admin on Sep 1, 2011 in |
Based on the principle of base catalyzed condensation reaction of 1, 2-diamines with carbonyl compounds, an efficient method for the synthesis of fused 1, 4-diazepines was developed. High yields were obtained for both electron-releasing as well as electron-withdrawing substituted 1, 4-diazepine derivatives by the mentioned...
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Posted by admin on Sep 1, 2011 in |
A reverse phase HPLC method is described for the determination of Ziprasidone HCl capsule by analytical method. Chromatography was carried out on an ODS C18 column using a mixture of buffer solution, acetonitrile and methanol (45: 40: 15v/v/v) as the mobile phase at a flow rate of 1.5mL/min. Detection was carried out at 230nm. The retention time of the drug was 7-9 min. The method produced linear responses in the concentration range of 50-150µg/mL of Ziprasidone .The method was found to be applicable for determination of the drug in...
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Posted by admin on Sep 1, 2011 in |
In case of cancer, Traditional Chinese medicine-based herbal medicines have gained increasing acceptance worldwide in recent years and are being pursued by pharmaceutical companies as rich resources for drug discovery. For many years, traditional Chinese medicines (TCM) have been applied for the treatment of cancers in China and beyond. Herbal remedies are clearly a complementary and alternative modality used frequently by patients with hemato-oncological neoplasias during the course of their specific treatment. Cancer is a leading cause of death worldwide. There are a lot of cancer causing agents which are divided as physical carcinogens, chemical carcinogens and biological carcinogens. But most of the carcinogens or causes of cancer are related to our lifestyle like diet, habit, occupation, radiation and some infection, etc. Chemoprevention is highly necessary to prevent cancer related preterm death. In this review, we are studied on the herbal medicines, whenever used in cancer treatment and easily available in market. Cancer is a major cause of death, and globally studies are being conducted to prevent cancer or...
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Posted by admin on Aug 1, 2011 in |
Substituted Quinoxaline have received considerable attention during last two decades as they are endowed with variety of biological activities and have wide range of therapeutic properties. A literature survey indicates that quinoxaline derivatives possess different pharmacological and biological activities, of which the most potent is anti-inflammatory activity. In view of above literature survey, we thought to synthesize a novel substituted quinoxaline...
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