Posted by admin on Aug 31, 2020 in |
Anti-inflammatory activity and the toxicity of Bohadschia vitiensis water extract were investigated by in-vitro models to evaluate the consumption of the extract by the local community to reduce arthritic-related pain. Specimens of B. vitiensis were collected from Mannar, Sri Lanka, and the water extract (WE) was prepared by removing visceral organs and incubating diced samples in distilled water, followed by freeze-drying. The WE was used to test acute toxicity, based on Danio rerio embryotoxicity assay and to evaluate anti-inflammatory activity based on in-vitro models; egg albumin denaturation, erythrocyte membrane stability, Nitric Oxide (NO) scavenging and Hydrogen Peroxide (HP) scavenging activities. The IC50 was calculated for each assay and compared with a standard reference drug. The qualitative zoo-chemical analysis was carried out while the presence of major nutrients was evaluated. According to the results, WE had a LC50 of 151.59 µg/ml for Danio rerio embryotoxicity assay. The anti-inflammatory activity against egg albumin denaturation (IC50 of 277.51 µg/ml) was reported while a maximum percentage inhibition of 32.09% was reported at 250...
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Posted by admin on Aug 31, 2020 in |
Salvia hispanica L. Well known as chia is gaining popularity day by day due to its nutritional value. This plant is native to Mexico, belonging to family Labiatae / Laminacea, and it was used as a superfood from ancient times. Chia is valued more due to its oil content as it consists of omega -3-alpha linolenic acid in higher amount along with various types of other nutrients, e.g., proteins, dietary fibers, antioxidants, etc. which is very beneficial to keep a person healthy and also it helps in prevention of many diseases like CVS, diabetes, obesity cancer and also it gives strength to our immune system. In the past few decades, we have noticed a certain growth in the market value of chia, and it is increasing day by day, not in a particular area or region but around the whole globe. In this paper, we have discussed all the important characteristics of chia (from its morphological characters to its pharmacological properties along with nutritional values and its today’s marketing...
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Posted by admin on Aug 31, 2020 in |
Catalase, guaiacol peroxidase and polyphenol oxidase are antioxidant enzymes that are important in the metabolism of reactive oxygen species and can be induced by environmental stresses including chromium (Cr), heavy metal toxic to living organisms. In-vitro regenerated shoots of carnation (Dianthus caryophyllus L.) were exposed to K2Cr2O7, and the activities of these antioxidant enzymes were analyzed. A significant reduction in the POD activity was observed at 2nd week of culture, followed by a slight increase in the activity in the 4th week of culture. Maximum PPO activity was detected during the 3rd week of culture, which was comparable to the control cultures. A significant reduction in CAT activity was found in the 4th week. The chlorophyll content did not change significantly in the shoot buds developed up to 4th week of...
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Posted by admin on Aug 31, 2020 in |
The liver is the principal site for metabolism and excretion in the body. The human liver metabolizes substances by various biochemical pathways, including oxidation, reduction, hydration, condensation, hydrolysis, conjugation or isomerization. Disorder of any of therefore mentioned process may lead to liver cell injury, what we call as hepatotoxicity, which in turn leads to many diseases. Such diseases are responsible for higher mortality rates worldwide. Hepatotoxicity can be due to medicines, chemicals, dietary disturbances, or herb induced liver damage via hepatotoxins. A number of herbal and herbomineral preparations are available in the Ayurveda, the traditional Indian medicine, which has been investigated for their hepatoprotective potential to treat different types of liver disorders. The use of natural elements to eliminate the root cause of the disease by restoring balance at the same time creates a healthy lifestyle to prevent the recurrence of imbalance. Herbal medicines have existed worldwide with long recorded history, and they were used in ancient Chinese, Greek, Egyptian, and Indian medicine for various therapies purposes. World Health...
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Posted by admin on Aug 31, 2020 in |
In the Unani system of medicine, different dosage forms of the drug are used; out of them powder dosage form is known as Safūf, which is an important dosage form and has been used frequently since long. There are many Unani preparations used in the form of Safūf to treat various diseases. Safūf –I Mu’allif (SM) is a polyherbal Unani formulation that is known to be used as Spermatogenic agent and semen thickening agent. The drug is also used to treat sexual disorders like premature ejaculation, nocturnal emission, sexual debility, etc. Physicochemical study and development of standard operating procedures (SOPs) of polyherbal Unani formulations are essential to assess the quality, purity, and efficacy and consistency of drugs. The study formulation consists of following ingredients Tāl Makhānā (Asteracantha longifolia Nees.), Sā’lab Miṣri (Orchis latiflolia L.), Singhārā Khushk (Trapa bispinosa Roxb.), Gond Kīkar (Acacia Arabica Willd.), Māzu Sabz (Quercus infectoria Oliv.), Maṣṭagi Rumi (Pistacia lentiscus L.), Nishāshtah Gandum (Triticum aestivum L), Shaker Sūfed (Saccharum officinarum L.). The main aim of this...
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