Posted by admin on Aug 31, 2016 in |
Introduction: Blood is the only oxygen transporter in the body and is crucial in saving lives. Research has failed to find a true substitute for blood and blood components The attitude, beliefs, and level of knowledge associated with blood donation will determine whether potential donors will donate blood or not. Methodology: A descriptive epidemiological study with cross sectional study design was conducted among blood donors attending the blood bank of SSKM Hospital. Result: It was found 67.08% of the donors had a knowledge score of less than 5. It was found that donors from urban areas, higher educational and socio-economic status as well as those who had previous history of blood donation had higher knowledge scores. This was statistically significant (p<0.05). Mass media like television and radio had an insignificant role in creating awareness as only 5% and 2% of the donors were made aware through these respectively. The most important source of knowledge for the donors was blood donation camps as an overwhelming 68% were made aware through...
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Posted by admin on Aug 31, 2016 in |
Diabetes Mellitus (DM) has emerged as a common endocrine disorder in the world and the prevalence of thyroid dysfunction is increasing at the same time. The thyroid hormones control insulin secretion. In hypothyroidism there is a reduction in glucose-induced insulin secretion by beta cells, and during thyrotoxicosis the insulin resistance will be increased. Type 2 diabetes mellitus patients with subclinical hypothyroidism are at risk of complications like neuropathy and cardiovascular events. Hence, there is a need to detect subclinical hypothyroidism in diabetic patients.50 type II DM patients were screened for thyroid function studies viz T3, T4 & TSH. 50 age and sex matched healthy volunteers were treated as controls and the results were correlated with fasting blood glucose levels and lipid parameters. The results showed a significant difference among the controls and the patients. It may be concluded from this study that there is hypothyroidsm in DM...
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Posted by admin on Aug 31, 2016 in |
Red blood cells (RBCs) is the primary target of human Plasmodium. Species. Occurs oxidative stress on uninfected and infected RBC and lead to hemoglobin (Hb) level decreased. The mechanism of decreased hemoglobin level are reduced survival time, diserythropoiesis and increased erythrolysis. Ascorbic acid and phenolics of TCW effectives to prevent RBCs from oxidative damage. Methods: The post test only randomized control group desain in 30 Swiss mices inoculated with PbA separated in 2 control groups K(+) and K(+)DHP, 4 groups of treatment X1, X2, X3 and X4. TCW treatments of 1mL and 2mL per 100g BW. Statistical analysis uses for parasitemia index and Hb levels was one way ANOVA test. Correlation of both variabel analyzed using Pearson’s test. Results: There were differences of the parasitaemia index (p<0.05) and mean±SD (%) K(+) (20.46±9.43), K(+)DHP (0.28±0.33), X1 (14.86±5.82), X2 (1.26±1.94), X3 (4.40±1.45) and X4 (0.32±0.40). There were significant differences in Hb levels (p<0.05) and mean±SD (g%)(8.46±1.36, 11.92±1.16, 9.92±1.77, 11.04±1.92, 11.06±0.80 and 12.80±1.16), multiple range test shown the differences of K(+) againts...
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Posted by admin on Aug 31, 2016 in |
Background: Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the rest of the body (i.e. the tissues). There it releases the oxygen to permit aerobic respiration to provide energy to power the functions of the organism in the process called metabolism. Several research studies have pointed out the role of vitamin supplementation and amelioration from exercise induced oxidative stress. Vitamin E, potential lipid soluble antioxidant has profound roles in preventing muscle fatigue and enhances exercise performance. Methods: In this study we have taken 96 subjects of which half of them were given Vitamin E supplement. Various biochemical analyses were done according to the standard protocols. Results: The results of this present study showed that Vitamin E supplementation with treadmill exercise can alter haematological parameters of the sedentary university students. Conclusion: It can be concluded from the data of the present study that the combined Vitamin E and treadmill exercise supplementation significantly alter the haemoglobin content and total count which can improve the performance...
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Posted by admin on Aug 31, 2016 in |
Medicinal plants are natural gift to human lives to promote disease free healthy life. Worldwide believe that herbal remedies are safer and less damaging to the human body than synthetic drugs. The heartwood of Pterocarpussantalinus (PSB) and the fruit of Phyllanthusemblica (PEF) are important medicinal parts with several ethnomedicinal properties. Keeping in view their importance, this work was carried out to investigate the qualitative, quantitative determination of crude phytocompounds and their effect on ethanol-induced haemolysis in human subjects. The phytochemical screening revealed the presence of some important active ingredients. In vitro studies showed that aqueous extracts of PEF and PSB possesses antioxidant as well reduced hemolytic activity on different subjects were found in the following order Smokers > alcoholic smokers > alcoholics. Our data shows that the active compounds present in PSW and PEF may offer protection against free radical mediated oxidative stress in RBC of humans with ethanol – induced...
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