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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

Inclusion in Web of Science (Thomson Reuters) - ESCI
Projected Impact Factor (2017): 0.59 , CiteScore (2017): 0.27
Five-Year Projected Impact Factor: 1.83

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Volume 10 (2019) - Issue 6, June

Review Articles

 
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1.

GENUS ALPINIA, A POTENTIAL POWERHOUSE OF BIOACTIVE: A REVIEW

Alpinia is the largest and most taxonomically complex genus in the Zingiberaceae family. This includes about 230 species and widely spread throughout forests in tropical and subtropical Asia. Many of species are herbs and rich sources of bioactive compounds that extensively used in various purposes ranging from its use in culinary, prevention of diseases and ornamental purposes. There is no report...

E. Kaliyadasa * and B. A. Samarasinghe

Department of Export Agriculture, Faculty of Animal Science and Export Agriculture, Uva Wellassa University, Badulla, Sri Lanka.

DOI: 10.13040/IJPSR.0975-8232.10(6).2644-53

2644-2653

709

510

2.

PARKINSONISM: A GENERAL MOTOR DISABILITY

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders in the population above 60 years of age. The movement abnormalities in PD are credited due to an imbalance between the acetylcholine and dopamine which results in uncontrolled movements. It is characterized using resting tremor, postural impairment, bradykinesia, and rigidity. The degeneration of midbrain dopaminergic...

R. Singh and A. Srivastava *

Hygia Institute of Pharmaceutical Education and Research, Lucknow, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2654-62

2654-2662

622

349

3.

TOWARDS SUCCESSFUL ADAPTATION OF PLASMODIUM KNOWLESI TO LONG-TERM IN-VITRO CULTURE IN HUMAN ERYTHROCYTES

Plasmodium knowlesi, a simian malaria parasite, is widely used as a malaria model and now characterized as a clinically significant parasite that can lead to outbreaks throughout most countries in Southeast Asia. Despite its importance, both fundamental and clinical studies of P. knowlesi have been impeded by the lack of a convenient in-vitro culture system partly due to the parasite’s preferenc...

F. S. Mohamad and N. Abu-Bakar *

School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.

DOI: 10.13040/IJPSR.0975-8232.10(6).2663-69

2663-2669

559

261

4.

AUTHENTICATION OF SEVEN INDIAN TRADITIONAL TYPES OF THE HERBAL DRUG TERMINALIA CHEBULA WITH SCIENTIFIC UPDATES – AN ADVANCED INSIGHT

The fruit of Terminalia chebula is an essential drug used in single and in many compound formulations of Indian traditional systems like Ayurveda & Siddha and Unani systems of medicine. This herbal drug is referred to as ‘The king of medicines’ which denote it’s efficacy and potency in treating diseases. The TCF is the richest source of phenols among other plants and is cherished with le...

D. D. Bai

PCIM, CCRS Project, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2670-87

2670-2687

633

291

5.

AN OVERVIEW ON ANALYTICAL METHODS FOR DAPAGLIFLOZIN – AN ANTIDIABETIC DRUG

Dapagliflozin (DAPA) is a drug of gliflozin class. It is a white crystalline solid. Dapagliflozin is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity. Dapagliflozin blocks glucose reabsorption into the kidney, resulting in the elimination of blood glucose through the urine. DAPA is not official in any pharmacopeia. It comes under EU Pharmaceutic...

B. V. Suma * and R. Deveswaran

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, M. S. Ramaiah University of Applied Sciences, Bangalore, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2688-92

2688-2692

587

236

Research Articles

 
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6.

OPTIMIZATION OF ULTRASOUND-ASSISTED EXTRACTION OF PHENOLIC COMPOUNDS FROM AMMI VISNAGA USING RESPONSE SURFACE METHODOLOGY

In this study, response surface methodology (RSM) was used to optimize ultrasound-assisted extraction (UAE) conditions for obtaining the maximum yield and content of phenolic compounds of Ammi visnaga extracts (EAV). Three independent variables including ethanol concentration (%), extraction time (time) and solvent-to-material ration (mL/g) were studied. The results showed that the optimal UAE con...

S. Aourabi *, S. Jennan, M. Sfaira and F. Mahjoubi

Laboratory of Materials Engineering, Modeling and Environment, Faculty of Sciences, USMBA Fez, Morocco.

DOI: 10.13040/IJPSR.0975-8232.10(6).2693-99

2693-2699

546

287

7.

DOSE DEPENDENT CARDIAC EFFECTS OF DOXORUBICIN IN WISTAR RATS: A BIOCHEMICAL AND HISTOPATHOLOGICAL ANALYSIS

Although doxorubicin is used widely in animal models to induce cardiotoxicity, serial dose-dependent cardiac effects have not been investigated in experimental animal models to date. Therefore, the objective of this study was to find out the dose-dependent changes of doxorubicin-induced acute cardiotoxicity, both biochemically and histopathologically in Wistar rats. Wistar rats were divided into n...

J. A. N. Sandamali *, R. P. Hewawasam, K. A. P. W. Jayatilaka and L. K. B. Mudduwa

Department of Medical Laboratory Science, Faculty of Allied Health Sciences, University of Ruhuna, Sri Lanka.

DOI: 10.13040/IJPSR.0975-8232.10(6).2700-10

2700-2710

426

164

8.

EFFECT OF ETHANOLIC EXTRACT PROPOLIS TRIGONA SPP. MALANG INDONESIA ON ISOLATE STAPHYLOCOCCUS AUREUS BIOFILM ARCHITECTURE FROM CHRONIC RHINOSINUSITIS A CONFOCAL LASER SCANNING MICROSCOPIC STUDY

Biofilm in chronic rhinosinusitis (CRS) is the infection by bacteria, which is difficult to overcome. It has recurrent infections, mucosal inflammation, and postoperative symptoms. Propolis is a natural product that is potential as an anti-biofilm choice. The purpose of this study was to determine the ethanolic extract propolis (EEP) effect on the morphology of Staphylococcus aureus biofilm. The p...

W. Hadi, E. Handoko, Noorhamdani and S. R. Prawiro *

Department of Clinical Microbiology Faculty of Medicine, University of Brawijaya, Malang.

DOI: 10.13040/IJPSR.0975-8232.10(6).2711-17

2711-2717

385

174

9.

ANTIFUNGAL ACTIVITIES OF PANGIUM EDULE REINW SEED EXTRACTS INHIBIT THE GROWTH OF ASPERGILLUS FLAVUS, PRODUCER OF AFLATOXINS, THROUGH THE IN-VITRO TEST

Aspergillus flavus is a famous fungus that produces aflatoxins. Aflatoxins are the most well known toxic and carcinogenic chemical prominent produced in nature. The fungus and aflatoxins are the main concern of the corn consumer. Pangi (Pangium edule Reinw) is a potential native plant to reduce infestation of the fungus A. flavus to prevent fungal contamination of food or feed. The research was un...

V. Membalik, Y. W. George, A. Rahman and A. Asman *

Department of Plant Pests and Diseases, Faculty of Agriculture, Hasanuddin University, Jalan Perintis Kemerdekaan KM X, Makassar, South Sulawesi, Indonesia.

DOI: 10.13040/IJPSR.0975-8232.10(6).2718-22

2718-2722

378

171

10.

ANTIOXIDANT ACTIVITY OF TWO WILD TEUCRIUM SPECIES FROM MOROCCO

The aim of the present study was to investigate antioxidant activity, total polyphenols and total flavonoids contents of extracts from two Moroccan Teucrium species (Teucrium polium and Teucrium aurum). The Antioxidant activity was evaluated in-vitro by three assays namely, free radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP) and t...

Y. El Atki *, I. Aouam, F. El kamari, A. Taroq, B. Lyoussi and A. Abdellaoui

Laboratory of Physiology Pharmacology and Environmental Health, Department of Biology, Faculty of Sciences Dhar Mehraz, University Sidi Mohamed Ben Abdellah, B.P., Atlas, Fez, Morocco.

DOI: 10.13040/IJPSR.0975-8232.10(6).2723-29

2723-2729

591

203

11.

RP-UPLC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION AND FORCED DEGRADATION STUDIES OF ELVITEGRAVIR, COBICISTAT, EMTRICITABINE AND TENOFOVIR DISOPROXIL FUMARATE IN SOLID DOSAGE FORM

A stability indicating method was developed and validated for simultaneous estimation of Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Disoproxil Fumarate (Tenofovir D F) in solid dosage form using RP-UPLC method. Waters Acquity UPLC system with Column Endoversilo C18 (50 × 2.1 nm, 1.8 μm) having PDA detector at 252 nm wavelength was used. Mobile phase having a mixture of 700 ml of Acet...

J. K. D. Tejaswi * and R. G. Rajan

Department of Pharmaceutical Analysis, College of Pharmaceutical Sciences, Acharya Nagarjuna University, Guntur, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2730-38

2730-2738

154

66

12.

THE PROTECTIVE EFFECTS ABELMOSCHUS ESCULENTUS PODS SKIN AND SEEDS AGAINST NICOTINE INDUCED LIVER, KIDNEY DAMAGE IN MICE’

Abelmoschus esculentus is one of the oldest urbane crops grown in many countries and widely distributed. Parts used of okra are fruit, leave seed, root wish showed to have numerous Medicinal significant uses. On the other hand, cigarette, smokers found to have a high a significant effect on liver kidney and other numerous organs in the body. Aim: The study aims to explore the possible protective e...

M. A. M. A. Bari *, H. M. B. Albadri and H. F. Hussein

Department of Therapeutics, Baghdad College of Medical Sciences, Iraq.

DOI: 10.13040/IJPSR.0975-8232.10(6).2739-47

2739-2747

183

59

13.

CAPSAICIN (C18H27NO3) AND PHYTOL (C20H40O) FROM CAPSICUM ANNUM L. LEAF DOCKED AGAINST SALIVARY GLAND PROTEIN OF CULEX QUINQUEFASCIATUS

Overpopulation leads to rapid urbanization, and industrialization has directed an unplanned town expansion with no sanitary facilities and proper wastewater disposal arrangements drains in the pond. Mosquitoes create a significant public health problem in India and serve as vectors for transmitting various diseases like malaria, filariasis, dengue, chikungunya, etc., to humans. This results in the...

C. A. Annapoorani *, G. Indumathi and K. Manimegalai

Department of Zoology, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2748-53

2748-2753

231

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14.

IN-SILICO DESIGN OF ANTIGENIC PEPTIDES AND MOLECULAR CLONING OF CYTOTOXIN ASSOCIATED GENE (cagA) OF H. PYLORI IN AN EXPRESSION VECTOR

Helicobacter pylori (H. pylori) is a spiral, gram-negative pathogen which causes gastric cancer along with MALT lymphoma. It is widespread among the gut microflora and stands first among the pathogens. Cytotoxin-associated gene (cagA) is thought to be the vital protein in the pathogenesis of gastric cancer. Since there are no available vaccines at the moment, and owing to the increasing antibiotic...

K. A. M. Al-Challabi *, A. S. J. Al-Muhanna and M. Sudhakar

Department of Microbiology, Faculty of Science, Ministry of Higher Education and Scientific Research, University of Kufa, Iraq.

DOI: 10.13040/IJPSR.0975-8232.10(6).2754-61

2754-2761

156

54

15.

DETERMINATION OF AMINO ACIDS IN TWO SPECIES OF RICCIA

Two species of Riccia, namely Riccia billardieri and Riccia discolor, were studied to detect various amino acids qualitatively as well as quantitatively through HPLC. Seven amino acids (histidine, serine, tryptophan, asparagine, tyrosine, valine, and isoleucine) were observed to be common in both the species but varying significantly in their quantities. Riccia billardieri contained additionally f...

S. Anand and S. Kapila *

Department of Botany, Panjab University, Chandigarh, Punjab India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2762-68

2762-2768

149

57

16.

FORMULATION AND IN-VITRO EVALUATION OF FAST DISSOLVING TABLETS OF LACOSAMIDE USING NATURAL SUPER DISINTEGRANTS

Fast dissolving tablets are those which disintegrates rapidly within the mouth and taken without consumption of water. The present work is concerned with the formulation and in-vitro evaluation of Lacosamide fast dissolving tablets. Lacosamide is a novel anti-epileptic drug used in the treatment of partial onset of seizures. The objective of this study was to improve the rapid onset of action of t...

C. Haranath *, C. S. Reddy, B. P. Kumar and K. A. A. Khan

Department of Pharmaceutics, Raghavendra Institute of Pharmaceutical Education and Research (RIPER), Near SK University, Chiyyedu, Anantapur, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2769-76

2769-2776

268

95

17.

ESTIMATION OF TOTAL ALKALOIDS IN WILD AND IN-VITRO REGENERATED TINOSPORA CORDIFOLIA

Tinospora cordifolia (Willd) Miers (Synonym: T. sinensis (Lour.) Merr.) is a genetically diverse plant known for its immense medicinal properties due to the presence of bioactive compounds among which alkaloids are most vital. So, the present study aimed to estimate the total alkaloid content in wild and in-vitro regenerated plant & callus tissue of Tinospora cordifolia. Different solvents, i....

Priti and S. Rani *

Department of Biotechnology, Kurukshetra University, Kurukshetra, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2777-84

2777-2784

149

55

18.

STUDY OF ANTI-LIPIDEMIC EFFECT OF LEMONGRASS (CYMBOPOGON CITRATUS) AQUEOUS ROOTS AND FLOWER EXTRACTS ON ALBINO MICE

Purpose/Aim: In the present study, we investigate the antilipidemic effect of the aqueous extract Cymbopogon citratus. Background: Lemongrass is an aromatic plant belonging to the Gramineae family. C. citratus has been cultivated over many years for medicinal purposes in different countries throughout the world. Earlier in research, it was reported that the elevated cholesterol concentration was s...

N. Abbas *, A. Rasheed, E. S. Ahmed, S. Ali, U. M. Irfan and M. H. AL-Sueaadi

Department of Medicinal Chemistry, Qassim University, College of Pharmacy, Qassim, KSA.

DOI: 10.13040/IJPSR.0975-8232.10(6).2785-89

2785-2789

198

72

19.

CLINICAL PHARMACIST ASSESSMENT OF MONITORING AND RESOLVING THE DRUG-RELATED PROBLEMS IN BIPOLAR DISORDER PATIENTS: A PROSPECTIVE, OBSERVATIONAL STUDY AT TERTIARY CARE TEACHING HOSPITAL

Background: Bipolar disorder is a chronic mental illness due to a different interval of manic and depressive phase, the patient may become more prone to DRP, which interfere with the patients’ health outcome. Hence, clinical pharmacist can contribute to managing the DRP through proper pharmaceutical care intervention. Method/Design: A prospective, observational study had been done with 286 parti...

A. S. Parihar *, M. S. Ganachari, B. V. Tekkalaki and S. C. Patil

Department of Pharmacy Practice, KLE College of Pharmacy, KLE Academy of Higher Education and Research (Deemed to be University), Belagavi, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2790-96

2790-2796

176

49

20.

DETERMINATION OF CHEMICAL COMPOSITION, TOTAL PHENOLIC CONTENT, TOTAL FLAVONOID CONTENT AND IN-VITRO ANTIOXIDANT CAPACITY OF VARIOUS ORGANIC EXTRACTS OF GYNURA CREPIOIDES LEAVES CULTIVATED IN MALAYSIA

Gynura crepioides, also known as Okinawa Spinach, belongs to the family Asteraceae, which is known to possess various medicinal properties. The present study was thus aimed at determining the GC-MS based chemical profiling, total phenolic content (TPC), total flavonoid content (TFC) and anti-oxidant (AO) capacity of the organic crude extracts such as hexane, chloroform-ethyl acetate, obtained from...

M. S. Khan *, S. K. Yusufzai, E. K. Sonny, M. Rafatullah and S. B. Ismail

Industrial Chemistry Programme, Faculty of Science and Natural Resources, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia.

DOI: 10.13040/IJPSR.0975-8232.10(6).2797-05

2797-2805

190

62

21.

COMPARATIVE EVALUATION OF ANTIDEPRESSANT ACTIVITY OF VARIOUS EXTRACTS OF NYCTANTHES ARBOR-TRISTIS

The present study evaluates the antidepressant activity of Nyctanthes arbor-tristis (NT). In the present study antidepressant effects of hydroalcoholic leaf extract (250 & 500 mg/kg) (NTL), flower extract (250 & 500 mg/kg) (NTF) and combination extract (leaf+flower extract in equal ratio) (250 & 500 mg/kg) (NTC) of Nyctanthes arbor-tristis were evaluated by the use of forced swim test....

A. Guglani, T. Joshi * and B. K. Singh

Department of Pharmaceutical Sciences, Bhimtal (Kumaun University), Nainital, Uttarakhand, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2806-11

2806-2811

180

50

22.

ANTI-OXIDATIVE, ANTIBACTERIAL ACTIVITY AND PHYTOCHEMICAL SCREENING OF ARTOCARPUS HETEROPHYLLUS SEED EXTRACTS

Artocarpus heterophyllus is an evergreen tree cultivated and consumed throughout Nepal; however, its seed has been neglected as compared to the fruit. The sample was screened for phytochemical evaluation, and general tests, DPPH activity, antibacterial activity, and total flavonoid content was also measured. Also, the potential of its use as functional food was highlighted. Phytochemical analysis ...

S. Kandel *, K. Baral, A. Gurung, B. Gurung, D. Adhikari, R. Gurung, B. Sapkota and A. Kaundinnyayana

School of Information Technology, Fanshawe College, Fanshawe College Boulevard, London, Ontario, Canada, N5Y 5R6.

DOI: 10.13040/IJPSR.0975-8232.10(6).2812-18

2812-2818

200

119

23.

ANTIBACTERIAL AND PHYTOCHEMICAL STUDIES ON THE LEAVES OF ADENOCALYMMA ALLIACEUM MIERS.

Adenocalymma alliaceum is an important medicinal plant belongs to the family Bignoniaceae. The antibacterial and phytochemical studies on the leaves of this plant were carried out by using the disc diffusion method and Thin Layer Chromatography. The methanolic leaf extract showed a brown colored band on TLC plate with an Rf value 0.25 represents the presence of sulfide compound. The extract was te...

S. Thomas * and S. P. Sabu

Department of Botany, St. Dominic’s College, Kanjirapally, Kottayam, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2819-22

2819-2822

161

52

24.

DISSOLUTION ENHANCEMENT OF POORLY WATER SOLUBLE EPROSARTAN BY HOT MELT EXTRUSION TECHNIQUE

Objective: The prodigious challenge in the pharmaceutical industries was to enhance the solubility and the permeability of those drugs as key factors to improve their bioavailability. Various techniques have been used to improve the drug water solubility and release profile, and solid dispersions are considered to be the most successful techniques. The aim of the present study was to improve the s...

M. R. Reddy

Gurunanak Institute of Technical Campus, Ibrahimpatnam, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2823-37

2823-2837

168

56

25.

SYNTHESIS OF NOVEL 1, 3-INDANEDIONE DERIVATIVES AND PHARMACOLOGICAL EVALUATION AS ANTI-MICROBIAL, ANTI-OXIDATIVE AGENTS

1,3-Indanedione derivatives, which are of wide interest because of their diverse biological and chemical applications. A series of novel 1,3-Indanedione derivatives are synthesized via KNOEVENAGEL condensing reaction mechanism by condensing 1,3-Indanedione with the 1-(4-aminophenyl) ethanone to form a styrylated indanedione leading to the formation of different Schiff base (imine) preparation by u...

S. S. Rani, Shivaraj * and N. J. P. Subhashini

Department of Chemistry, University College of Science, Osmania University, Tarnaka, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2838-44

2838-2844

147

79

26.

NOVEL RP-HPLC AND UV METHOD DEVELOPMENT AND VALIDATION FOR INOTUZUMAB OZOGAMICIN IN BULK AND ITS PHARMACEUTICAL DOSAGE FORM

A simple, Precise, Accurate method was developed for the estimation of Inotuzumab Ozogamicin by RP-HPLC and UV technique. Chromatographic conditions used were stationary phase Discovery c18 150 × 4.6 mm, 5 m. Mobile phase O- phosphoric acid buffer: Acetonitrile in the ratio of 50v:50v and the flow rate were maintained at 1 ml/min, detection wavelength at 240nm, column temperature was set to 30 º...

S. K. Mastanamma *, S. K. Reehana and M. Hari

Department of Pharmaceutical Analysis, University College of Pharmaceutical Science, Acharya Nagarjuna University, Nagarjunanagar, Guntur, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2845-51

2845-2851

150

55

27.

EVALUATION OF MULTITARGETED ANTIPSYCHOTIC ACTIVITY OF UNMADGAJAKESARI – A HERBOMINERAL FORMULATION – AN ANIMAL EXPERIMENTAL STUDY

Schizophrenia is a chronic and complex mental disorder characterized by hallucinations and delusions that significantly affect emotions, behavior, and mental processes. Currently used antipsychotics are characterized by the multireceptor mode of action (antagonism of dopamine D2 and serotonin receptors), there is no consensus regarding an "ideal" target engagement. Moreover, they are associated wi...

R. Joseph *, V. Pandit, A. Wele, G. Deshmane and M. Pawar

Department of Pharmacology, Bharati Vidyapeeth Dental College and Hospital, Katraj, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2852-60

2852-2860

146

51

28.

VALIDATED KINETIC SPECTROPHOTOMETRIC DETERMINATION OF DRUGS USING ALKALINE POTASSIUM PERMANGANATE OXIDATION

A simple and sensitive kinetic method is described for the determination of drugs viz., Bendamustine hydrochloride (BEN), Ciprofloxacin hydrochloride (CIP), Dorzolamide hydrochloride (DOR), Pantoprazole sodium (PAN), Warfarin sodium (WAR). This method is based upon a kinetic investigation of drug oxidation with alkaline potassium permanganate. Kinetics of the oxidation reaction is followed spectro...

M. Prashanthi and G. Venkateshwarlu *

Department of Chemistry, Osmania University, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2861-69

2861-2869

129

41

29.

SYNTHESIS NEW MOLECULARLY IMPRINTED POLYMERS FOR THE SELECTIVE ELECTRODES OF ISOPROPAMIDE FROM PHARMACEUTICAL SAMPLES

Liquid electrodes of polymers imprinted with Isopropamide (ISP) were synthesized based on precipitation polymerization mechanism. The molecularly imprinted polymer (MIP) and non-imprinted polymers (NIP) were synthesized using (ISP) as a template. In the polymerization process, 2-Hydroxyethyl meth acrylate (2-HEMA) and 2-Vinyl pyridine (2-VP) were used as monomers. Di-vinylbanzene (DVB) was used as...

A. M. Dhari * and Y. K. Al-Bayati

Department of Chemistry, College of Science, University of Baghdad, Al-Jadryia, Baghdad, Iraq.

DOI: 10.13040/IJPSR.0975-8232.10(6).2870-78

2870-2878

125

44

30.

FORMULATION AND IN-VITRO CHARACTERISATION OF VILAZODONE IMMEDIATE RELEASE TABLETS

The aim of the present study is to develop and evaluate the immediate release tablet of Vilazodone by direct compression method. The superdisintegrant crospovidone (CP), croscarmellose sodium (CCS), sodium starch glycolate (SSG), and Locust beam gum were used for the immediate release of drug from the tablet. Optimization of superdisintegrant concentration that can control the release of the drug ...

P. S. Kumar * and N. Sravani

Department of Pharmaceutics, Browns College of Pharmacy, Khammam, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2879-83

2879-2883

140

49

31.

COMPARISON OF PCR AND CELL CULTURE FOR HUMAN ADENOVIRUS DETECTION IN GASTROENTERITIS AND RESPIRATORY TRACT INFECTED NORTH INDIAN CHILDREN

Acute gastroenteritis (AGE) and acute respiratory tract infection (ARTI) are the most common causes of morbidity and mortality in young children worldwide. This study aimed to analyze the sensitivity and specificity of laboratory diagnostic methods. We compared to cell culture and polymerase chain reaction (PCR) technique for the detection of Human adenovirus (HAdV) in AGE and ARTI children below ...

R. Tripathi, S. Awasthi, A. Zia, S. Saxena, D. Singh, A. Pandey, P. Bhattacharya and T. N. Dhole *

Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2884-91

2884-2891

153

47

32.

STEROL COMPOSITION AND ANTI-ATHEROSCLEROSIS EFFECTS OF XESTOSPONGIA MUTA EXTRACTS BY INCREASING TRANSCRIPTIONAL ACTIVITY OF SR-B1 PROMOTER

Methanolic crude extract, diethyl ether fraction and sterol composition of Xestospongia muta were screened for cytotoxicity activity against HepG2 (liver hepatocellular) cells by MTS assay. Potential sterol mixture was profile using Gas Chromatography-Mass Spectrometry (GC-MS analysis), and luciferase assay were performed to further analyze its potentially on anti-atherosclerosis effects by increa...

N. A. Azemi, N. Ismail *, L. Abu-Baka and T. S. T. Muhammad

Institute of Marine Biotechnology, Universiti Malaysia Terengganu, Kuala Terengganu, Terengganu, Malaysia.

DOI: 10.13040/IJPSR.0975-8232.10(6).2892-97

2892-2897

126

48

33.

ANTIOXIDANT AND ANTI-DIABETIC POTENTIAL OF OPERCULINA TURPETHUM (L.) SILVA MANSO LEAF

‘Natural curing agents for diabetes’ is a matter of world research. Diabetes, the gift of altered life pattern, affected considerably larger proportion of world population. Ancient Indian literature has the treasure of knowledge regarding natural curing agents. The plant Operculina turpethum (Convolvulaceae) is one among them. The plant root is used in many Ayurvedic formulations to treat vari...

A. V. Jalaj * and P. M. Radhamany

Department of Botany, University of Kerala, Kariavattom, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2898-01

2898-2901

184

63

34.

A FACILE NOVEL SYNTHESIS OF ThO2/Fe3O4 NANOCOMPOSITE WITH ENHANCED PHOTOCATALYTIC ACTIVITY FOR THE DEGRADATION OF MALACHITE GREEN UNDER VISIBLE LIGHT IRRADIATION

An innovative magnetically separable ThO2/Fe3O4 nanocomposite was successfully synthesized by hydrothermal method. The synthesized ThO2/Fe3O4 nanocomposite was characterized by UV-DRS, FT-IR, XRD, HR-TEM, BET, and TGA techniques. XRD and HR-TEM images displayed the overall spherical shape and confirmed the formation of well crystalline ThO2/Fe3O4 nanocomposite. The catalytic efficiency of ThO2/Fe3...

R. Arumugam, P. Periakaruppan * and R. Selvanathan

Department of Chemistry, Thiagarajar College, Madurai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2902-10

2902-2910

151

50

35.

GC-MS ANALYSIS OF BIO-ACTIVE COMPOUNDS IN METHANOLIC EXTRACT OF ZIZIPHUS MAURITIANA FRUIT

Present study highlights that plant as a source of medicine has been inherited and is an important component of the health care system in India. Ziziphus mauritiana fruit (Rhamnaceae), one of the medicinally important plants commonly found in subtropical countries, was chromatographically evaluated in the present work for the identification of various phytochemical compounds found in it. The phyto...

P. Kushwaha, S. S. Yadav, V. Singh and L. K. Dwivedi *

Institute of Biomedical Sciences, Bundelkhand University, Jhansi, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2911-16

2911-2916

148

54

36.

FORMULATION AND EVALUATION OF LOSARTAN POTASSIUM COMPRESSION COATED TABLETS BY OKRA GUM AS A BINDER

The purpose of the present study was to formulate Losartan potassium compression-coated tablets using okra gum as a binder along with synthetic hydrophilic polymers like various grades of Hydroxypropyl methylcellulose (HPMC) and compare the different parameters. The effect of different concentration of okra is to be used in the formulations with varying concentration of the polymers, elucidating t...

S. Chatterjee and R. Mazumder *

Department of Pharmaceutics, Calcutta Institute of Pharmaceutical Technology and Allied Health Sciences, Howrah, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2917-22

2917-2922

133

70

37.

NOVEL AMORPHOUS SOLID DISPERSIONS OF CANAGLIFLOZIN HEMIHYDRATE IN EUDRAGIT® E PO

The purpose of this research was to develop novel solid dispersions (SDs) of BCS class IV drug, canagliflozin hemihydrate (CFZ) using Eudragit® E PO (EE PO) as a carrier, to enhance its solubility and dissolution rate. Solvent evaporation technique was used to prepare SDs. The SDs were evaluated for saturated solubility, in-vitro dissolution study, solid-state characterization using FTIR, DSC, XR...

R. Agrawal *, N. Patel and M. Raval

Department of Pharmaceutics, Krupanidhi College of Pharmacy, Carmelaram, Bengaluru, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2923-33

2923-2933

154

48

38.

IN- VITRO ANTIOXIDANT PROPERTIES, ACUTE AND SUBACUTE TOXICITY STUDIES OF TEPHROSIA CALOPHYLLA ON ALBINO WISTAR RATS

The evaluation of acute oral toxicity of chloroform extract of Tephrosia calophylla (CETC) and methanolic extract of Tephrosia calophylla (METC) and sub-acute toxicity of CETC was done on albino Wistar rats. The animals (female) were divided into four groups containing 3 animals in each group normal control, and 200, 400 and 800 mg/kg of freshly prepared extracts respectively, every 24 h orally fo...

V. J. Samuel and A. R. Mahesh *

Department of Pharmaceutical Chemistry, College of Pharmaceutical Sciences, Dayananda Sagar University, Bangalore, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2934-40

2934-2940

129

53

39.

PHYTOCHEMICAL ANALYSIS AND IN-VITRO ANTICANCER ACTIVITY OF DURANTA ERECTA L. (VERBENACEAE)

The aim of the present work is the evaluation of anticancer activity of Duranta erecta L. stem extracts and also an investigation of the phytoconstituents from the different extracts of the plant. Chloroform, ethyl acetate, methanol and aqueous extracts of Duranta erecta L. stem were tested for their anticancer activity on three cancer cell lines, i.e., MCF-7 (Breast), HL-60 (Leukemia), and HT-29 ...

A. S. Wagh * and S. R. Butle

Department of Pharmacognosy, School of Pharmacy, S.R.T.M. University, Nanded, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2941-46

2941-2946

122

66

40.

THE ACTIVITY OF EURYCOMANONE DERIVATIVES ON CANCER CELL LINES

Eurycomanone from the roots of Eurycoma longifolia Jack (ELJ) has been reported to exhibit anticancer activity. Four of ester eurycomanone derivatives: eurycomanone dibutyrate, eurycomanone monovalerate, eurycomanone dimethoxybenzene, and eurycomanone disuccinate were synthesized for knowing their activities on cancer cell lines T47D, MCF-7, Hela, WIDR and Vero cells. The cancer activity was evalu...

H. Yusuf *, D. Satria and Zulkarnain

Department of Pharmacology, Faculty of Medicine Universitas Syiah Kuala, Banda Aceh, Indonesia.

DOI: 10.13040/IJPSR.0975-8232.10(6).2947-50

2947-2950

121

45

41.

IN-VITRO ANTIBACTERIAL ACTIVITIES OF AJWA DATE FRUIT (PHOENIX DACTYLIFERA L.) EXTRACT AGAINST SELECTED GRAM-NEGATIVE BACTERIA CAUSING GASTROENTERITIS

Gastroenteritis, especially those caused by bacterial pathogens, remains as one of the major health issues in developing countries. Despite the availability of treatment, people are turning their interest in consuming certain food for its therapeutic value given the adverse effects of medications. This includes the consumption of date fruits (Phoenix dactylifera L.). This study aims to determine t...

N. Abdullah, N. F. M. Ishak and W. S. W. Shahida *

Faculty of Medicine and Health Sciences, University Sains Islam Malaysia Level 13, Menara B, Persiaran MPAJ, Jalan Pandan Utama, Pandan Indah, Kuala Lumpur, Malaysia.

DOI: 10.13040/IJPSR.0975-8232.10(6).2951-55

2951-2955

258

68

42.

RISK OF DEVELOPING DEPRESSION AND ITS IMPACT ON QUALITY OF LIFE IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME – A SOUTH INDIAN SCENARIO

Polycystic ovary syndrome (PCOS) is one of the most common reproductive endocrine disorders, affecting the patient’s psychological functioning and satisfaction with life. Settings and Design: Tertiary care hospital based case-control study was conducted. Material and Methods: the study was effectuated in 372 patients in total, including an equal number of cases and controls.PHQ-9 was used to det...

A. Mukundan * and S. Jayakumari

School of Pharmaceutical Sciences, Vels University, Pallavaram, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2956-61

2956-2961

157

43

43.

ACUTE A SUB-CHRONIC TOXICITY AND IMMUNOMODULATORY ACTIVITY OF AN AQUEOUS EXTRACT OF EUPHORBIA RESINIFERA IN RODENTS

Euphorbia resinifera Berg. (ER) an endemic Moroccan plant has been used to treat different diseases. In spite of its toxicological potential, no scientific report until now was made to evaluate in-vivo neither the toxic effect nor its immunomodulatory activity. The objective was to evaluate the safety of an aqueous extract (AE) of ER in-vivo and its effect on the biochemical, immunological and his...

Z. Issiki, F. Daoudi, E. M. Mtairag, S. Rais, F. Marnissi, Y. Zaid, A. Naya and M. Oudghiri *

Immunology and Biodiversity Laboratory, Department of Biology, Faculty of Sciences Aïn Chock, Hassan II University of Casablanca, Maârif, Casablanca, Morocco.

DOI: 10.13040/IJPSR.0975-8232.10(6).2962-69

2962-2969

119

51

44.

ASSESSMENT OF QUALITY OF LIFE IN DIALYSIS AND NON-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS

Quality of life is an essential measure that proves the effectiveness of health care, health level, and well-being. Kidney diseases are one of the major health problems that affect Quality of life. This study aimed to assess the quality of life in dialysis (CRF-D) and non-dialysis (CRF-ND) chronic renal failure (CRF) patients using Kidney Disease Quality of Life-short form (KDQOL-SFTM) and identif...

N. Venkateswaramurthy *, M. S. Islam, R. C. Habeeba and R. Sambathkumar

Department of Pharmacy Practice, J. K. K. Nattraja College of Pharmacy, Kumarapalayam, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2970-74

2970-2974

158

94

45.

FTIR SPECTROPHOTOMETRIC METHOD FOR THE SIMULTANEOUS ESTIMATION OF ARTEMETHER AND LUMEFANTRINE IN BULK AND FORMULATIONS

A FTIR method was developed to estimate Artemether and Lumefantrine simultaneously in bulk as well as in formulations. It is based on the measurement of absorption of radiation at the absorption band of ether at 1113.10-1091.77 cm-1 for ART and phenyl substitution band at 893.65-857.08 cm-1 for LUM, because those absorption bands did not occur in excipients present in a pharmaceutical preparation....

S. S. Prasanth * and S. Rukku

Al-Shifa College of Pharmacy, Kizhattur, Perinthalmanna, Malappuram, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2975-80

2975-2980

116

56

46.

GC-MS ANALYSIS OF BIOACTIVE COMPONENTS ON THE FRUIT EXTRACTS OF ARTOCARPUS HIRSUTUS LAM.: A POTENTIAL WILD EDIBLE PLANT

Wild fruits play a significant role in human nutrition, especially as sources of carbohydrates, proteins, vitamins, minerals, dietary fibers, and enormous medicinal potential. Local people in different parts of the country have learned to live on many wild edible fruits available around their localities. Artocarpus hirsutus Lam. is an important wild edible fruit plant belongs to the family Moracea...

C. P. Neha * and A. K. Abdussalam

Department of Post Graduate Studies and Research in Botany, Sir Syed College, Taliparamba, Kannur, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2981-84

2981-2984

147

61

47.

FORMULATION DEVELOPMENT AND EVALUATION OF METOPROLOL SUCCINATE SUSTAINED RELEASE AND HYDROCHLOROTHIAZIDE IMMEDIATE RELEASE BILAYER TABLET

Bilayer tablet concept has been investigated to develop a combination of sustained and immediate release formulations. The present study aims to develop and evaluate to provide a combined therapy through a single tablet in which combinations of Metoprolol succinate and Hydrochlorothiazide were used. The pharmacokinetics advantage of this formulation was, drug release from the fast releasing layer ...

S. Murugesan *, P. S. Rasmi and P. Ramasubramaniyan

Department of Physics, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2985-92

2985-2992

127

47

48.

HYDROXYAPATITE AND Zn-HYDROXYAPATITE SYNTHESIS USING CALCIUM FROM LAKE MANINJAU PENSI SHELLS AND RESISTANCE TEST ON BACTERIA

HAp and Zn-HAp Synthesis with several concentrations of Zn (5%, 10%, 15%, and 20%) w/w using Ca precursor from Maninjau Lake pensi shells was done with the sol-gel method. XRF for three hours obtained 96.525% Ca content in the form of CaO. XRD result for the synthesized samples showed the same diffraction pattern as the standard HAp (ICSD: 154493) phase which the intensity decreases with the addit...

W. A. Putra, N. Jamarun *, A. Agustien, Zilfa, U. Septiani and Safni

Department of Chemistry, Faculty of Mathematics and Science, Andalas University, Padang, West Sumatera, Indonesia.

DOI: 10.13040/IJPSR.0975-8232.10(6).2993-97

2993-2997

122

57

49.

SELECTING PROTEIN STRUCTURE/S FOR DOCKING-BASED VIRTUAL SCREENING: A CASE STUDY ON TYPE II INHIBITORS OF VEGFR-2 KINASE

In this study, 36 crystal structures available with type I-V inhibitors of VEGFR-2 kinase in the RCSB PDB were classified into DFG-in/-out conformation using visual analysis and KLIFS database. The focus was on Type II inhibitors as most kinase inhibitors belong to this category. Therefore, the crystal structures with DFG-out confirmation with a type II inhibitor were selected depending on the res...

H. R. Bhojwani and U. J. Joshi *

Department of Pharmaceutical Chemistry, Prin. K. M. Kundnani College of Pharmacy, Cuffe Parade, Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2998-11

2998-3011

201

51

50.

GC-MS ANALYSIS, PHYTOCHEMICALS AND IN-VITRO ANTIOXIDANT PROPERTIES OF ROOT EXTRACTS OF PHLOGACANTHUS THYRSIFLORUS NEES., WESTERN ASSAM, INDIA

The Phlogacanthus thyrsiflorus roots have been used by the tribal population of western Assam to treat the hepatic disorder. The present study focuses on phytochemical screening, GC-MS analysis and in-vitro antioxidant activities using different extracts. Plant total phenolics, flavonoids, reducing power assay and antioxidant activity was evaluated. DPPH, FRAP, ABTS, Metal chelating activity,...

H. Boro, K. Mashahary and S. Das *

Department of Biotechnology, Bodoland University, Kokrajhar, Assam, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).3012-21

3012-3021

125

62

51.

ANTIEPILEPTIC ACTIVITY OF RUBIADIN ISOLATED FROM THE ROOTS OF RUBIA CORDIFOLIA IN MICE

Epilepsy is a disorder of the central nervous system. A seizure occurs when the brain’s nerve cells misfire and generate a sudden uncontrolled surge of electrical activity in the brain. Seizures can be controlled with modern medicines and surgical techniques and are found to have so many side effects. Natural products from folk remedies are an alternative source of anti-epileptic drugs with bett...

A. Verma *, V. S. Mahalwal and B. Kumar

Sanskar College of Pharmacy & Research, Ghaziabad, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).3022-28

3022-3028

132

55

52.

DEVELOPMENT OF NOVEL INJECTABLE FORMULATION OF CLOPIDOGREL BY QbD APPROACH

Clopidogrel, a poorly water-soluble drug, has been the mainstay of platelet management in acute coronary syndrome (ACS) or percutaneous coronary intervention (PCI) for over a decade. Since Clopidogrel is a prodrug and requires hepatic metabolism for activation, it exhibits a slower onset of action upon oral administration. This time-lag before the onset on the action is highly undesirable for the ...

J. Hadia *, T. Pethani and A. Dudhrejiya

Department of Pharmaceutical Sciences, Saurashtra University, Rajkot, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).3029-37

3029-3037

171

49

53.

EVALUATION OF IN-VIVO ANALGESIC ACTIVITY OF ARGYREIA CYMOSA (ROXB.) SWEET

The current research was accomplished to assess the analgesic activity of Argyreia cymosa (A. cymosa) methanolic extracts (MEAC) at 200 and 400 mg/kg. The entire herb was extracted with the methanol (MEAC). Acute oral toxicity of the extract was according to OECD-423 recommendations. Analgesic activity was explored by utilizing hot plate, tail immersion and acetic acid-evoked writhing models. In a...

V. Gunji * and G. Seru

Department of Pharmacognosy and Phytochemistry, A. M. Reddy Memorial College of Pharmacy, Uppalapadu, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).3038-44

3038-3044

136

60

54.

ASSESSMENT OF OFF-LABEL DRUG USE IN A TERTIARY CARE HOSPITAL

Off-label use is defined as the use of pharmaceutical drugs for an unapproved indication or unapproved age group, dose, dosage or route of administration. An off-label use provides the best intervention for the patient when medical evidence justifies its use, but this can also be harmful due to the increased risk of adverse drug reactions when lacking a solid evidentiary basis. Hence, the aim was ...

K. T. Mathew, S. Kishor, S. E. Jess, V. S. Dutt and V. Sivakumar *

PSG College of Pharmacy, Peelamedu, Coimbatore, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).3045-52

3045-3052

179

82

55.

THE UNDERSTANDING AND ADHERENCE OF HIV-INFECTED PREGNANT WOMEN TO THERAPY IN A SOUTH-EASTERN STATE OF NIGERIA: A CROSS-SECTIONAL ASSESSMENT

Introduction: Appropriate understanding and adherence to antiretroviral regimens are important requisites to the presentation of good outcomes in the Prevention of Mother-to-Child Transmission (PMTCT) of HIV/AIDS. Objectives: This study aimed to evaluate the understanding and level of adherence to antiretroviral regimens among HIV-infected pregnant women. The factors that affect the level were als...

A. Isah *, I. E. Ogbu, K. C. Amorha, M. O. Adibe, J. M. Okonta, C. N. Aguwa

Department of Clinical Pharmacy and Pharmacy Management, University of Nigeria, Nsukka, Enugu State, Nigeria.

DOI: 10.13040/IJPSR.0975-8232.10(6).3053-61

3053-3061

137

65

56.

IN-VIVO ANTIOXIDANT AND ANTIHYPERLIPIDEMIC ACTIVITY OF SYZYGIUM CERASOIDEUM EXTRACTS IN RATS

Antioxidant and antihyperlipidemic activities of the extracts of Syzygium cerasoideum were investigated by studying their in-vivo effects on triton and cholesterol induced hyperlipidemia. Highest antioxidant activity was exhibited by methanolic extract followed by chloroform extract of S. cerasoideum. In triton induced hyperlipidemic model, the groups treated with the extracts of S. cerasoideum an...

S. Sadik *, K. M. Geetha and Vasia

Department of Pharmacology 1, Oxbridge College of Pharmacy, Bengaluru, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).3062-72

3062-3072

153

56

57.

DESIGN, SYNTHESIS, MOLECULAR DOCKING AND EVALUATION OF ANTIMICROBIAL ACTIVITY OF 4- AMINO-N- [(4-OXO-2-(PHENYLAMINO)-4H-CHROMEN-3-YL) METHY-LENE]BENZENESULFONAMIDE AND THEIR DERIVATIVES

2-Anilino-3-formylchromones are obtained in high yield by rearrangement of differently substituted C-(4-oxo-4H[1]-benzopyran-3-yl)-N-phenylnitrones. These compounds undergo various facile nucleophilic substitution reactions leading to the synthesis of various pharmacologically active chromone based novel heterocyclic systems like sulphonamides. The C-2 and C-3 are the main positions in the chromon...

A. Chopra, L. Singh *, V. K. Kapoor, R. Dhingra and N. Dhingra

C. G. C. College of Engineering, Landran, Mohali, Punjab, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).3073-84

3073-3084

137

50

58.

TEMPERATURE STRESS MEDIATED CONSEQUENCES ON PHYSIOLOGY AND SECONDARY METABOLITES OF DATURA STRAMONIUM (L.)

Datura stramonium (L.), a multipurpose plant of Himalayan regions which possess antiseptic, sedative, antidiarrhoeal properties used for treating various diseases which include treatment of ulcer, skin disorder, jaundice, fever, heart diseases, etc. To evaluate the temperature stress-mediated morphological, physiochemical, and antioxidative defense in Datura stramonium, plants were subjected to di...

Shriya, M. Sharma *, A. Kumari and S. Choudhary

Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).3085-91

3085-3091

156

48

59.

THERAPEUTIC EFFECT OF BELLAMYA BENGALENSIS LAMARCK BY INHIBITION OF OXIDATIVE STRESS IN EXPERIMENTAL ARTHRITIC MODEL

Objective: Oxidative stress and generation of free radicals leads to several chronic inflammatory diseases like arthritis, diabetes mellitus, cancer, etc. Arthritis is an immune-mediated systemic disorder known to impair the quality of life. In spite of development of drug discovery, therapeutic targeting of arthritis is still not satisfactory. Bellamya bengalensis has been long known for used in ...

S. Bhattacharya, A. Adhikari *, A. Chanda and T. K. Sur

Department of Pharmacology, R. G. Kar Medical College, Kolkata, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).3092-00

3092-3100

187

42

60.

PHARMACOGNOSTIC AND PHYTOCHEMICAL INVESTIGATION OF POTENTIALLY IMPORTANT PLANTS OF WESTERN GHATS, INDIA

Objective: The Indian traditional system of medicine, namely Ayurveda and Siddha, are primarily based on the use of the whole plant or different parts of plant singly or in combination to make multifactorial formulations. The use of plant drugs, however, demands correct identification of species and the characterization of phytoconstituents. Materials and Methods: The plants reported for their wou...

S. R. Wayal * and S. S. Gurav

Department of Pharmacognosy, JSPM’s Charak College of Pharmacy & Research, Wagholi, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).3101-08

3101-3108

116

60

61.

MEASUREMENT OF NATURAL RADIOACTIVITY IN BUILDING MATERIALS SAMPLES BY USING (HPGe) SYSTEM

In the present work, we have measured natural radioactivity in twelve building materials samples for four kinds (Brick, cement, gypsum and sand) obtained from some Iraqi governorates by using High Purity Germanium (HPGe) radiation detectors system. The results of measurements have shown that the average values specific activity concentrations for 238U, 232Th and 40K which were equal to (24.236 ± ...

H. M. Abdullah, K. S. Jassim * and J. F. Mohammad

Department of Physics, College of Education for Pure Science, University of Babylon, Hilla-Babylon, Iraq.

DOI: 10.13040/IJPSR.0975-8232.10(6).3109-12

3109-3112

136

59