Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
RECENT ADVANCES IN IMPURITY PROFILING OF PHARMACEUTICALS
Impurities will be present in all drug substances and drug products, i.e. nothing is 100% pure if one looks in enough depth. The current regulatory guidance on impurities accepts this, and for drug products with a dose of less than 2 g/day identification of impurities is set at 0.1% levels and above (ICH Q3B (R2), 2006). For some impurities, this is a simple undertaking as generally available anal...
5850
2410
ENHANCEMENT OF DISSOLUTION AND BIOAVAILABILITY OF EZETIMIBE BY SPRAY DRIED MICROPARTICLES USING HP-β- CYCLODEXTRIN POLYMER
Objective: Enhancement of oral bioavailability of poorly water soluble drugs is the most challenging aspects of drug development. It is very important to find appropriate formulation approaches to improve the aqueous solubility and bioavailability of poorly aqueous soluble drugs. Ezetimibe is a new lipid lowering agent in the management of hyper-cholesterolemia. The drug is water-insoluble, lipoph...
9295
2016
MOLECULAR DOCKING STUDIES OF NOVEL IMIDAZOLE ANALOGS AS HIV-1-RT INHIBITORS
Molecular docking studies of 102 newly designed N-substituted imidazoles was performed in the non nucleoside inhibitory binding pocket of reverse transcriptase enzyme of wild type as well as resistant strains of HIV-1 virus with PDB ID 1RT2, 1JLB, 3BGR and 1FK9 respectively by using Glide 5.0 to carry out a binding mode analysis of the designed imidazoles. Results generated from this study indicat...
3760
1653
MORPHOLOGICAL AND MORPHOMETRICAL STUDY OF CORONOID PROCESS IN HUMAN MANDIBLES
Background: The coronoid process of mandible is thin flat triangular process from the ramus of the mandible. This varies in the shapes and size. It gives attachment to two main muscles that is temporalis and masseter muscle. The coronoid process is the favourable donor site. A Coronoid process graft can be used for alveolar defects repair, orbital floor repair, maxillary augmentation, repair of no...
5213
2197
A RETROSPECTIVE STUDY OF PRESCRIBING PATTERN FOR ACUTE RESPIRATORY INFECTIONS IN CHILDERN IN A TERTIARY CARE TEACHING HOSPITAL
Objective: To study prescribing pattern for acute respiratory infections in children attending outpatient department of Paediatrics, J.L.N. Hospital, Ajmer, Rajasthan. Material and Method: The study was carried out retrospectively by analyzing the copies of prescriptions of patients who had visited the O.P.D. of the paediatrics department of J.L.N. Hospital Ajmer. A total of 350 prescriptions havi...
3860
1437
PULSATILE DRUG DELIVERY OF CANDESARTAN CILEXETIL FOR CARDIOVASCULAR COMPLICATIONS
The aim of current investigation was to formulate and evaluate an oral time controlled drug delivery system to achieve timed release of Candesartan cilexetil for the treatment of cardiovascular complications. Blood pressure rises early in the morning which can leads to hypertension and congestive cardiac failure. Attempt has been made to develop a drug delivery which releases the drug based on cha...
3785
1626
THE RISK OF HYPERGLYCEMIA ASSOCIATED WITH THE USE OF PRESCRIBED MEDICATIONS
Hyperglycemia is a deleterious consequence of uncontrolled diabetes and an adverse effect of many common therapeutic drugs. Identification of drug-induced hyperglycemia is necessary for reducing morbidity or mortality associated with high blood glucose levels. The aim of the present study was to assess risk of unrecognized drug-induced hyperglycemia in patients admitted to King Abdulaziz Medical C...
8748
1752
HPTLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF OXYCLOZANIDE AND LEVAMISOLE HYDROCHLORIDE IN TABLET DOSAGE FORM
This paper describes a new, simple, precise, and accurate HPTLC method for simultaneous estimation of Oxyclozanide and Levamisole hydrochloride as the bulk drug and in tablet dosage forms. Chromatographic separation of the drugs was performed on aluminium plates pre-coated with silica gel 60 F254 as the stationary phase and the solvent system consisted of Toluene: acetone: ammonia (5:5:0.04 v/v/v)...
3906
1874
HISTORICAL OVERVIEW, DEVELOPMENT AND NEW APPROACHES IN DESIGN OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS AND ANGIOTENSIN RECEPTOR ANTAGONISTS PART II
The renin-angiotensin system (RAS) plays an important role in pathogenesis of hypertension, congestive heart failure, and chronic renal failure. In addition to a discussion of the current understanding of the chemical structures and the modes of action of angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor (ATR) antagonists, review includes their SAR analysis and chemical modif...
5969
2379
STUDY AND COMPARISON OF AMINO ACIDS IN RED AND GREEN APPLES
Apples are rich of vital components to the human health, such as the amino acids, but their presence differ according to the type and colour of the apples. In this study we compared the concentrations of amino acids in the peels and pulps of red and green apples, by using the HLPC for analysis. 16 amino acids were found with different concentrations according to the locality in which they exist in...
8268
2035