Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF AMBROXOL HCl IN PHARMACEUTICAL DOSAGE FORM
Rapid, sensitive, specific and validated colorimetric methods have been developed for the quantitative estimation of ambroxol HCl in bulk and dosage form. The current method was developed based on oxidation of ambroxol with Gibb’s reagent (method I) and p-diethyl amino benzaldehyde in toluene (method II). The formed intense colour complex was measured at 537.2 nm and 438.4 nm respectively. Under...
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SYNTHESIS AND BIOLOGICAL EVALUATION OF COUMARIN CLUBBED OXAZINES
Coumarin segment have been reported broad spectrum of different biological activities with the oxazine derivatives. In view that we have synthesized newer coumarin clubbed 4-(4-fluorophenyl)-6-substituted phenyl-2H-1,3-oxazin-2-amine and screened for their biological studies. 4-(4-fluorophenyl)-6-substituted phenyl-2H-1,3-oxazin-2-amine IIa-j condensed with 4-Methyl-6-nitro-2-oxo-2H-chromen-7-yl c...
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SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF MORPHOLINE MANNICH BASE DERIVATIVES
In the present study 10 morpholine mannich base derivatives were synthesized by three component reaction of morpholine, N-phenylacetamide and various substituted benzaldehydes. Progress of the reaction was monitored by thin layer chromatography and the compounds synthesized were characterized by ATR and 1HNMR techniques. Antimicrobial activity of the synthesized compounds was evaluated against gra...
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1237
DIETHYLSTILBESTROL (DES) INDUCED ENDOMETRIOSIS IN BALB/C MICE TREATED WITH MMP-2 AND 9 INHIBITORS-I
Diethylstilbestrol (DES) is an endocrine disturbing compound it can mimic and perform like a natural hormone, which mimics estradiol by binding to the estrogen receptor. This compound mainly reproductive target, so in this study used to induce endometriosis. Endometriosis is an estrone dependent constant gynaecological disorder. Here it, intends to induce endometriosis and treated by the MMP inhib...
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DEVELOPMENT AND CHARACTERIZATION OF BILAYER TABLET CONTAINING TRAMADOL AND PREGABALIN AS A GASTRIC BUOYANT DRUG DELIVERY SYSTEM FOR COMBINATION PHARMACOTHERAPY OF NEUROPATHIC PAIN
Experiments were performed to design, develop and characterize bilayer buoyant tablets with Tramadol (TH), immediate release layer and Pregabalin (PGB), sustained release layer. Super disintegrants like crosscarmellose sodium and sodium starch glycolate, for IR layer where as Hydroxypropyl methylcellulose (HPMC-K4M, HPMC-K100M) and sodium carboxymethyl cellulose, as sustaining polymers for SR laye...
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EFFECT OF METHYL PARATHION (AN ORGANOPHOSPHATE) ON BIOCHEMICAL CONTENTS OF FRESH WATER CAT FISH HETEROPNEUSTES FOSSILIS (BLOCH)
The present work was planned to study the effect of methyl parathion an organophosphate compound (OP) on biochemical contents of fresh water cat fish Heteropneustis fossilis. The exposure of fish to the sub-lethal concentrations of the toxicant methyl parathion was investigated and the variations were observed in biochemical contents in different tissues of the fish i.e. gill, liver, intestine, mu...
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FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL TABLETS OF PROPRANOLOL PREPARED USING NATURAL POLYMER
Propranolol is beta-blocker and it is widely used in the management of hypertension. Propranolol is used to treat tremors angina, hypertension, heart rhythm disorder and other heart or circulatory conditions. The mucoadhesive buccal tablets of propranolol were papered by wet granulation method using natural polymer like Vigna mungo powder. The compatibility studies of drug and excipient were perfo...
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SOCIAL AND BIOLOGICAL FACTOR OF TYPE 2 DIABETES MELLITUS
Diabetes mellitus is reaching potentially epidemic proportions in India. The level of morbidity and mortality due to diabetes and its potential complications are enormous and pose significant healthcare burdens on both families and society. In this study 400 blood serum samples were collected from various laboratories and diabetic centre in and around Tirupur, Tamil Nadu, India. Blood glucose leve...
4542
987
STUDY ON SAFETY AND EFFICACY OF DIFFERENT MODALITIES IN THE POST-OPERATIVE PAIN MANAGEMENT IN A TERTIARY CARE TEACHING HOSPITAL
ABSTRACT: Background: Postoperative pain control is an important part of effective postoperative care. However, 30 - 80% of postoperative patients complain about moderate to severe post-surgical pain as a result of the surgical procedure or a pre-existing disease. Aim: To assess the safety and efficacy of different modalities of postoperative pain management in post surgical wards of a tertiary ca...
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IN VITRO ANTIMICROBIAL SCREENING OF MEDICINAL PLANTS AGAINST CLINICAL AND PHYTOPATHOGENIC BACTERIA AND FUNGI
The positive results of screening medicinal plants for antimicrobial activity forms primary platform for phytochemical and pharmacological studies in future. The work was undertaken to evaluate the antimicrobial activity of four medicinal plants viz., Sesbania grandiflora, Epiphyllum oxypetalum, Nyctanthes arbor-tristis, and Vetiveria zizanioides. Leaves were extracted using water and ethanol as s...
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