Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
GC-MS ANALYSIS AND IN VITRO ANTILEISHMANIAL ACTIVITY OF ETHYLACETATE FRACTION OF ALLIUM CEPA (EAFAC)
In this study, GC-MS analysis shown that ethyl acetate fraction of Allium cepa (EAFAC) (band one) consists of 55 compounds which shown antileishmanial activity. (IC50 73.1 ± 2.1 ug/ml) is the inhibitory concentration which is observed for ethyl acetate fraction of Allium cepa (EAFAC) (band one). Leishmania major is the specie used for this leishmanicidal assay. In this bioassay, Amphotericin B (I...
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KINETIC AND MECHANISTIC STUDIES ON OXIDATION OF DONEPEZIL HYDRO CHLORIDE BY CHLORAMINE – T IN BASIC MEDIUM
Donepezil hydrochloride is United States Food and Drug Administration (USFDA) approved drug marketed under the trade name “Aricept” used for the treatment of mild to moderate alzheimer disease. The aim of the current investigation was Kinetic and mechanistic study of donepezil hydrochloride by sodium-N-chloro-p-tolunesulfonamide or chloramine-T (CAT) in NaOH medium was studied at 308 K. the re...
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EVALUATION OF HYDROXYL RADICAL SCAVENGING ACTIVITY OF ETHANOLIC EXTRACT OF THYMUS SERPYLLUM
Ethanolic extract of the aerial parts of Thymus serpyllum was evaluated for antioxidant activity. As many diseases in today’s world are due to free radicals, finding antioxidants of herbal origin can lead to development of safe herbal medicines for these diseases. Hydroxyl radical scavenging method was used to evaluate the antioxidant activity of Thymus serpyllum in the present study. The result...
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ASSESSMENT OF DRUG USE PATTERN, THEIR COST AND SAFETY IN EMERGENCY DEPARTMENT AT A TERTIARY CARE TEACHING HOSPITAL, RAJKOT
Introduction: The practice of emergency medicine has the primary mission of evaluating, managing and providing treatment to patients with unexpected injury or illness. The emergency department of a tertiary care unit of a developing country is faced with the problem of heavy patient load and a paucity of human and economic resources. So, this study was conducted with the objective of Studying patt...
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ANTIBACTERIAL ACTIVITY OF HEXANIC EXTRACT OF RUTA GRAVEOLENS ON KLEBSIELLA PNEUMONIAE- A COMMON POST- ORTHOPEDIC SURGERY INFECTION
Introduction: Klebsiella pneumoniae is one of the most frequent infection organism following orthopedic surgeries and specifically total hip arthroplasty. Recently, attitude toward herbal medicine is being popular both in people and health care systems. Ruta graveolens is a traditional herbal remedy Iranian medicine and some other countries with a wide spectrum of therapeutic utilities. Our purpos...
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TWENTY EIGHT DAYS ORAL ADMINISTRATION ASSESSMENT OF HYDNORA AFRICANA THUNB. AQUEOUS ROOT EXTRACT ON KEY METABOLIC MARKERS OF WISTAR RATS
Hydnora africana Thumb (Hydronaceae) is a parasitic flowering plant with significant global ethnomedicinal value. This study evaluated the toxicological effects of the acute and sub-acute dosing treatments of the aqueous root extract of Ha in male and female wistar rats using OECD guidelines 423 and 407. For the acute study, the extract was administered to the animals at single oral graded doses o...
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FORMULATION, DESIGN AND CHARACTERIZATION OF MUCOADHESIVE BUCCAL FILM OF NEBIVOLOL USING FACTORIAL DESIGN
The present investigation was to formulation and development of fast dissolving mucoadhesive buccal film of nebivolol by using solvent casting method. Nebivolol is a third-generation cardio selective β1-blocker undergoes extensive metabolism in the liver, gastrointestinal disturbance, abdominal pain after its oral administration and resulting in to a poor (10-12%) bioavailability. In order to imp...
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VARIATION IN MEMBRANE ELECTROCHEMICAL POTENTIAL OF PLASMODIUM INFECTED ERYTHROCYTES
Membrane electrochemical potential or zeta potential (ZP) is a feature of the molecular profile of the cell membrane and the two-dimensional arrangement of its charge-bearing molecules. Plasmodium species, the causative agents of malaria, are intracellular parasites that remodel host erythrocytes by expressing their own proteins on erythrocyte membranes. In the present study the variation in the Z...
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FORMULATION AND EVALUATION OF COLON TARGETED DRUG DELIVERY SYSTEM OF FLURBIPROFEN FOR TREATMENT OF RHEUMATOID ARTHRITIS
In this present research work, the aim was to develop ileo-colonic targeted mini-tablets filled capsule system of flurbiprofen for treatment of rheumatoid arthritis. In the present study pH independent colon targeted system was developed and evaluated. SMEDDs of poorly water soluble drug flurbiprofen were prepared to enhance its dissolution rate and bioavailability. Mini-tablets of flurbiprofen we...
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ISOLATION AND CHARACTERIZATION OF BIOFILM FORMING BACTERIA FROM URINARY TRACT INFECTED PATIENTS
A biofilm is a microbial determined sessile group portrayed by cells that are irreversibly appended to a substratum or interface or to each other. Biofilms are the main cause for increase in virulence and antibiotic resistance of microorganisms. Both gram positive and gram negative pathogens are known to produce biofilms. Due to the production of biofilm, the bacteria adhere to the surface strongl...
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