Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
DEVELOPMENT AND IN-VITRO CHARACTERIZATION OF SUSTAINED FLOATING HOLLOW MICROSPHERES CONTAINING LABETALOL HCL FOR THE TREATMENT OF HYPERTENSION
Aim: The present work for the development and in-vitro evaluation of sustained floating hollow microspheres (SFHM). Materials and methods: Sustained floating hollow microspheres were prepared by means of HPMC K4M, ethylcellulose and sodium alginate in various concentrations by using the solvent evaporation method using dichloromethane as solvent. The floating hollow microspheres of Labetalol HCl w...
968
474
IN-VITRO COMPARATIVE QUALITY ASSESSMENT OF DIFFERENT BRANDS OF DICLOFENAC SUPPOSITORIES AVAILABLE IN THE KUMASI METROPOLIS, GHANA
Drugs play a vital role in maintaining and promoting health. The safety, efficacy, and quality of the drugs must be assessed to protect the health of the user. Diclofenac is a cyclooxygenase inhibitor and one of the most useful, effective commercially available NSAIDs used in the management of pain. Many different brands and dosage forms (tablets, oral powder, and suppositories) of diclofenac are ...
757
431
NEW CO-PROCESSED EXCIPIENTS WITH MICROCRYSTALLINE CELLULOSE AND ISOMALT BY FLUID BED. AN OPTION FOR DIRECT COMPRESSION EXCIPIENTS
Objective: To elaborate and characterize new co-processed excipients for direct compression use. Methods: The new co-processed excipients were obtained with different proportions of microcrystalline cellulose (Avicel® PH101) and Isomalt (galenIQ® 800), using Starch® 1500 and Plasdone® K-25as binding agents in a fluid bed. Rheological characterization was performed; to determine their deformati...
741
321
FORMULATION AND EVALUATION OF SOLID-SELF NANO EMULSIFYING DRUG DELIVERY SYSTEM OF FAMOTIDINE
The main objective of the study was to formulate and evaluate solid self nano emulsifying drug delivery systems (SNEDDS) of famotidine (BCS class-IV drug), a histamine receptor antagonist used in case of ulcers, Zollinger-ellison syndrome. Liquid SNEDDS was formulated using oils like oleic acid, arachis oil, surfactants like Tween 20, Tween 80, etc., and co-surfactants like Transcutol-P, polyethyl...
724
349
AMELIORATIVE POTENTIAL OF BETULINIC ACID AND ROTUNDIC ACID ON NEPHROTOXICITY INDUCED BY MERCURY CHLORIDE IN RATS
Mercury toxicity is the most hazardous problem emerging in the world as its accumulation is escalating persistently through the increased utility of mercury in medicinal, industrial, and domiciliary usage. Subjection to mercury illustrates a consequential provocation to humans and other living biomes. The intention of the present research was to investigate the shielding potential of betulinic aci...
679
249
FORMULATION AND EVALUATION OF CLOPIDOGREL BISULFATE CAPSULE LOADED NANOPARTICLES
The present study aims to formulate and evaluate clopidogrel bisulfate capsule-loaded nanoparticles. Clopidogrel bisulfate nanoparticles were produced by the nano-precipitation method and emulsification solvent evaporation method using ethylcellulose polymer at different ratios and characterized for particle size drug entrapment efficiency dissolution testing scanning electron microscopy imaging (...
1106
500
PHYTOCHEMICAL ANALYSIS AND ANTIBACTERIAL ACTIVITY OF DIFFERENT CITRUS FRUIT PEELS
Citrus fruit is a very rich source of Vitamin C, A, E, and flavonoids, alkaloids, and minerals. Citrus fruits are medicinal plants that present rutaceae family and include some fruits such as orange (Citrus sinensis), kinnow (Citrus reticulata), mosambi (Citrua ltmetta), grapefruit (Citrus maxima) lime, pomelo lemon. Antibacterial antiviral, antifungal activity of different solvent extracts (Ace...
2239
831
DERIVATIVE SPECTROPHOTOMETRIC METHODS FOR THE ANALYSIS AND STABILITY STUDIES OF RANOLAZINE IN BULK AND DOSAGE FORMS
Objectives: The present study aimed to develop simple and accurate first and second-order derivative spectrophotometric methods (1D and 2D) for the assay and stability studies of Ranolazine (RAN) in bulk and dosage forms. Methods: The original UV spectrum of RAN solution in methanol was differentiated instrumentally to generate the first and second derivative spectra which were measured at 278 nm ...
709
275
FORMULATION AND EVALUATION OF SUSTAINED-RELEASE TABLET OF TRAZODONE HYDROCHLORIDE
The main objective of this study was to formulate a Sustained release tablet by wet granulation method. A sustained release tablet of trazadone hydrochloride was prepared by using synthetic polymer. The prepared tablets were evaluated for their diameter, thickness, drug content, Hardness, friability, weight variation. The thickness and diameter of the tablet range from 5.43±0.288 to 5.76±0.05 an...
960
641
PHARMACOGNOSTIC EVALUATION OF LAGERSTROEMIA SPECIOSA FRUIT
Lagerstroemia speciosa (Lythraceae), commonly known as Banaba which bears attractive and colourful pink or purple flowers. The leaf of the plant is used as a remedy for the treatment of diabetes. The seed, root, stem bark of the plant has shown a promising pharmacological effect. Fruits are used for diarrhoea, mouth ulcers. Pharmacognostic evaluation of leaves stems and stem bark is available in t...
849
357