Objective: To assess the drug utilization evaluation of antihypertensive agents in diabetic and non-diabetic patients with chronic kidney disease. Method: Retrospective observational study was conducted in inpatient Nephrology department of B.B.R. Hospital from Sep 2016 to Feb 2017 and 155 case records of patients diagnosed with CKD and HTN, above 18 yrs of age, belonging to both genders were coll...
The aim of this present investigation is to identify the most important risk factor for cancer by means of a mathematical model. The study begins with considering some types of cancer viz. breast, colorectum as well as lung and bronchus cancer as most of the cancer patients suffer from these types of cancers. Teaching-Learning-Based Optimization technique is applied to sorting out the most lethal ...
PREVALENCE of AmpC β-LACTAMASE IN PLASMID RESISTANT GENE FROM UTI CLINICAL ISOLATES BY MOLECULAR TECHNIQUES
Objective: To detect the prevalence of Plasmid resistant AmpC β-lactamases gene in clinical isolates of gram negative organisms from UTI patients which produce resistance against multiple antibiotics. The gene coding for AmpC β-lactamases is also present in E. coli & Klebsiella species was not expressed because due to lack of promoter region, but the transfer of chromosomal genes to plasmids...
The whole plant of Cocculus pendulus (J.R. & G. Forst.) Diels is reported to have quality medicinal values in traditional system of medicines. The various physico-chemical parameters included determination of extractive value, loss on drying, ash values, fluorescence analysis, HPTLC analysis and preliminary phytochemical analysis were performed. The preliminary identification of Cocculus pendu...
SCREENING OF SULPHUR OXIDIZING BACTERIA FROM SULPHUR SPRINGS OF SAHASTRADHARA REGION OF DEHRADUN, UTTARAKHAND, INDIA
Sulphur water is commonly used as the remedial source for treating skin infections and eradicating pathogenic microbes causing infection. The sulphur water is the source of sulphur oxidizing bacteria which is the source of different secondary metabolites which has potential killing activity against different skin borne infections. In the present investigation, the study was performed to isolate an...
ANTI-INFLAMMATORY ACTIVITY OF STEM BARK OF TECOMA STANS (L.) JUSS. EX KUNTH AND ESTIMATION OF GALLIC ACID
Tecoma stans is a well-known traditional plant in India. The plant can be used in diabetes, digestive problems, and rheumatism and as antimicrobial. The aim of the study is to evaluate the anti-inflammatory activity of extracts of the stem bark of Tecoma stans (L.) by in-vitro and in-vivo methods. Ethyl acetate and alcoholic extract showed better anti-inflammatory activity by Human red blood cell ...
N-[MORPHOLINO (4-NITROPHENYL) METHYL] NICOTINAMIDE AND ITS METAL COMPLEXES: SYNTHESIS AND EXPLORATION OF THEIR BIOACTIVITY
Synthetic organic compounds, containing relatively higher number of nitrogen attracting interest in the current medical research due to their utility in chemotherapy. The development of new medicines with more number of nitrogen atoms in their structural framework is an important challenging task for medicinal chemists. The lipophilicity of Mannich bases and their metal complexes enables them to b...
A properly designed system will provide a high degree of assurance that every step, process, and change has been properly evaluated before its implementation. Validation is an important step carried out in order to control the entire process, and the process adapted to produce itself must assure that process will consistently produce the expected results and maintain the desired quality of the fin...
ASSESSMENT OF PRIMARY HEALTH CARE WORKERS’ KNOWLEDGE, ATTITUDES AND PRACTICES ON UNCOMPLICATED MALARIA MANAGEMENT IN PLATEAU STATE, NIGERIA
Overcoming the scourge of malaria infection is possible when healthcare workers have good levels of understanding and attitudes towards the disease, which will influence their treatment practices. This study assessed healthcare workers’ levels of knowledge, attitudes, and practices (KAP) in uncomplicated malaria treatment at primary healthcare (PHC) facilities in Plateau state, Nigeria. The stud...
The ethanol extract of Hibiscus esculentus Linn roots inhibited the formation of oxygen derived free radicals were screened for their in vitro antioxidant activity. Stems leaves and root of selected plants were dried at 45°C and powdered for extraction. Extraction was performed with methanol. By employing DPPH (2, 2-diphenyl-1picrylhydrazyl radical) scavenging assays, it was shown that all the et...