Ascidians are rich source of novel bioactive agents as potential source of therapeutic drugs. Evaluation of antioxidant potential of ascidians, Eudistoma viride and Didemnum psammathodes extracts was undertaken. In DPPH radical scavenging assay E. viride II showed 34% to 93% scavenging activity and D. psammathodes II showed 45% to 96% scavenging activity in different ascidian concentrations. In re...
STUDIES ON THE DEVELOPMENT AND EVALUATION OF COLON SPECIFIC DRUG DELIVERY SYSTEM CONTAINING MEBEVERINE
The main aim of this study was to develop Mebeverine colon specific drug delivery system with increased stability of drug in stomach and small intestine. This stability of drug was achieved by coating of the drug core with Chitosan and Ethyl cellulose polymers by direct compression using tablet punching machine. Mebeverine was a drug whose therapeutic role is in the treatment of Irritable Bowel Sy...
Context: Ziziphus mistol (mistol) fruits and their derivate product (arrope) have been traditionally used as food and in folk medicine for the treatment of a wide variety of diseases including bronchopulmonary disorder. Objective: The objective of this study is to evaluate the antitussive and expectorant effects of Z. mistol ethanol extract (EE), aqueous extract (AE) and arrope (Ar). Materials and...
POTENTIAL POSITIVE EFFECT OF ORAL PYRIDOXINE ALONE AND IN COMBINATION WITH MECLIZINE ON CIGARETTES SMOKING DURING TENDAYS’ TRIAL
Purpose: Several medications are currently available for trying smoking cessation, such as nicotine replacement therapy or antidepressants. This study investigates potential effect of Meclezine-B6 combination; and B6 tablets administrated orally for possibility of reducing number of cigarettes smoked per day during 10 days. Methods: Using placebo control study. In which adult smokers' volunteers w...