Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
MOLECULAR-LEVEL COMPARATIVE ANALYSIS ON HUB-PROTEINS OF PARKINSON’S DISEASE WITH SELECTED SYNTHETIC DRUGS USING AN IN-SILICO APPROACH
Physical interactions between proteins are cardinal to biological processes. To restore their function, proteins must interact with one another. Hub proteins are densely interconnected proteins with a wide range of biological significance and are also to blame for several illnesses, including cancer, autoimmune disorders, and neurodegenerative diseases. The most prevalent of these is Parkinson's d...
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PRECLINICAL SAFETY EVALUATION OF BERBERINE IN COMBINATION WITH GLICLAZIDE
Allopathic drugs are generally prescribed for Diabetes Mellitus (Type-II) patients. As the disease is chronic in nature, it necessitates the use of alternative medicine(s) either to supplement the existing allopathic therapy and/or to reduce the associated side effects with their chronic use. The use of herbal drugs is presumed to be safe option due to fewer side effects. However, evaluation of sa...
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DRUG UTILIZATION EVALUATION OF ANTIBIOTICS IN INDIAN TERTIARY CARE HOSPITAL
Background: Infections occur when viruses, bacteria, or microbes enter the body and multiply. Control of infection is achieved by using antibiotics; hence scrutiny of antibiotic prescribing patterns is an important aspect of quality and standards of clinical practice. Objective: To evaluate and analyse drug utilization and prescription pattern of antibiotics in various in-patient departments of th...
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IN-SILICO VALIDATION AND PHARMACOLOGICAL ACTIVITY OF POTENT ANTI VIRAL AND ANTI INFLAMMATORY ETHNO MEDICINAL PLANTS USED BY TRADITIONAL HERBALISTS WITHIN THORANGTLANG WILDLIFE SANCTUARY, MIZORAM, NORTH-EAST INDIA
Background: Our study aims to document the use of ethnomedicinal plants reported by herbalists in treating ailments that are becoming more prevalent. Using an ethnobotanical approach and in-silico studies, will advise further prevalence and give precedence to future pharmacological studies. Methods: The application of the plants was reported by 75 informants. From the 51 reported plants, 20 plants...
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DESIGN AND CHARACTERISATION OF AMOXYCILLIN LOADED DENTICAP USING MUCOADHESIVE GUM ISOLATED FROM FRUIT PULP OF ZIZIPHUS MAURITIANA L.
Novel drug delivery approach by using natural polymers is a newer area of formulation development. The oral drug delivery in the buccal cavity to treat the dental infections has some limitations such as slow onset of actions and is also affected by the first pass metabolism. In order to overcome these challenges plant derived mucoadhesive gum from the fruit pulp of Ziziphus mauritiana L.(ZM) is us...
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DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF AMLODIPINE AND VALSARTAN IN ITS BULK AND TABLET DOSAGE FORM BY USING THE QUALITY-BY-DESIGN APPROACH
This study describes the implementation of a Quality by Design approach to develop and validate the RP-HPLC for amlodipine and valsartan. The reaction surface method optimizes by adopting the three-level Box Behnken design. The three factors selected are methanol and water concentrations (mobile phase), flow rate, and wavelength. The developed chromatographic method was validated against the ICH Q...
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EVALUATION OF ANTI-NOCICEPTIVE EFFECT OF ETHANOLIC EXTRACT OF VANILLA PLANIFOLIA SEEDS IN ANIMAL MODELS OF PAIN
Background: Pain is warning signal of the underlying pathology and is also essential for the diagnosis. Vanilla planifolia (VP) as per literature has analgesic activity. Analgesics like NSAIDs and Opioids are used for treating pain. Adverse effects limits their long-term use. Therefore, there is always a need of more effective and safe drugs. Objective: To evaluate the analgesic activity of ethano...
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A SIMPLE METHOD DEVELOPMENT, VALIDATION AND QUANTIFICATION OF LENVATINIB IN PHARMACEUTICAL DOSAGE FORM USING ZERO ORDER AND FIRST-ORDER DERIVATIVE NOVEL SPECTROPHOTOMETRIC METHODS
Simple, very Sensitive, rapid, and accurate novel spectro-photometric methods were developed to estimate Lenvatinib in Pharmaceutical dosage form using zero- and first-order derivative spectrophotometry. The solutions of Lenvatinib standard and sample were prepared using analytical grade methanol. The spectrophotometric estimation of lenvatinib was carried out at 240 nm in the zero-order method an...
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QUANTITATIVE ESTIMATION OF PHYTOCONSTITUENTS AND ANTI-HISTAMINIC ACTIVITY OF QUISQUALIS INDICA LINN
The objectives of the present study were to determine the total phenolic content, flavonoid content, and anti-cataleptic activity of chloroform and methanolic extract of the roots of Quisqualis indica. The crude extracts were investigated for total phenolic and flavonoid content using the Folin-Coicalteu method and the Aluminum chloride colorimetric method. It was found that the total phenolic con...
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EVALUATION OF PRELIMINARY TRIAL BATCHES OF FORMULATIONS CONTAINING ORAL HYPOGLYCEMIC DRUGS METFORMIN HYDROCHLORIDE AND CANAGLIFLOZIN
The in-vitro drug release profile from a hydrophilic matrix tablet is influenced by the viscosity of the gel layer formed due to its polymer hydration, and it depends on various other physical properties like a drug: polymer ratio water-solubility and particle size of the drug, particle size and type of the polymer, type of diluents used, and temperature of media. The drug release profile of diffe...
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