THE EFFECT OF PSYCHIATRIC EDUCATION ON THE ATTITUDE OF MEDICAL STUDENTS OF GUILAN UNIVERSITY OF MEDICAL SCIENCES TOWARD PSYCHIATRY
Introduction: While many medical students have a special talent in psychiatry, attracting them to this specialty is a problem. The purpose of this study was to examine the impact of psychiatric education on the attitude of medical students on psychiatric patients. Method: In this observational study, 200 medical externs and interns were recruited. Before and after attending the 4-week psychiatry e...
PROTECTIVE EFFECT OF BAUHINIA TOMENTOSA L. EXTRACT AGAINST GENTAMICIN INDUCED NEPHROTOXICITY IN WISTAR MALE ALBINO RATS
The aim of the present study was to explore the effect of aerial parts of Bauhinia tomentosa extract against gentamicin-induced nephrotoxicity. Thirty male Wistar albino rats were divided into five groups of six animals each. Animals served as Group I (normal control 5 ml/kg b.wt, p.o), Group II (toxic control), and Group III and IV (treatment groups 200 and 400 mg/kg b.wt, p.o) and Group V (stand...
The objective of the present investigation was to develop a sustained release (SR) tablets of Doxazosin Mesylate by wet granulation technique using a combination of synthetic polymers (Eudragit RS-100 and Eudragit RL-100). Different batches of Doxazosin Mesylate sustained release tablets were prepared by using microcrystalline cellulose as diluents by wet granulation technique. The compatibility o...
PARENTERAL ADMINISTERED SUSTAINED RELEASE PIPERINE MICROPARTICLES INTENDED FOR TREATMENT OF LIVER FIBROSIS
The objective of this work was to formulate and characterize microparticles containing piperine, and evaluate their activity against carbon tetrachloride (CCl4)-induced liver toxicity. Piperine microparticles were formulated by o/w emulsion solvent evaporation technique using poly-ε-caprolactone as a polymer. Four different microparticle formulations (PM1, PM2, PM3, and PM4) were prepared by vary...
TRANSGENIC LYCOPERSICUM ESCULENTUM MILL (TOMATO) PLANT AS BIOREACTOR FOR THE PRODUCTION OF HUMAN NEUTROPHIL PEPTIDE-1 (HNP-1): A USEFUL PROTEIN BASED PHARMACEUTICAL
The term ‘transgenic plant’ is defined as the plants that are produced in the lab by artificial insertion of genes sometimes from the same species and sometimes entirely from the different kingdom. A major advantage of transgenic plant because of which it gains a lot of importance in today’s world is developing it for producing pharmaceutically useful compounds. Hence, they are act...
ANTIDIABETIC AND LIPID LOWERING EXTENUATING IMPACT OF GLYCINE MAX LEAVES (SOYABEAN) IN TYPE II DIABETES MELLITUS SUBJECTS
Diabetes mellitus is possibly the world’s largest growing metabolic disease. Currently, a challenge is to identify such healthy foods that remain in the realms of obscurity and to establish them as functional foods to prevent the progression of metabolic complications. Glycine max is indigenous to India and is used extensively in the traditional system of medicine to treat diabetes, reduces coro...
POLYETHYLENE GLYCOL (PEG) SUPPORTED AMINO DENDRIMERS (DENDRITIC TRIBLOCK COPOLYMER) FOR DELIVERY OF METHOTREXATE (MTX)
Dendrimers are synthetic, highly branched, nanosized, monodisperse macromolecule which proving their applicability in different areas like diagnosis, drug delivery, gene delivery, molecular encapsulation etc. Due to their widespread applications, scientific community is continually engaged in developing newer dendrimers with advanced properties. In the present study, amino dendrimers are synthesiz...
A SIMPLE STABILITY INDICATING HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF LEVOCETIRIZINE DIHYDROCHLORIDE, PHENYLEPHRINE HYDROCHLORIDE AND PARACETAMOL IN PHARMACEUTICALS
An accurate and precise HPLC method was developed and validated for simultaneous determination of Levocetirizine dihydrochloride, Phenylephrine hydrochloride and Paracetamol in syrup formulations. The separation between Levocetirizine dihydrochloride, Phenylephrine hydrochloride, and Paracetamol was achieved within 20 min using an L1 column of 100 × 4.6 mm, 3 µ dimension using gradient programme...
STUDY OF ANTI-LIPIDEMIC EFFECT OF LEMONGRASS (CYMBOPOGON CITRATUS) AQUEOUS ROOTS AND FLOWER EXTRACTS ON ALBINO MICE
Purpose/Aim: In the present study, we investigate the antilipidemic effect of the aqueous extract Cymbopogon citratus. Background: Lemongrass is an aromatic plant belonging to the Gramineae family. C. citratus has been cultivated over many years for medicinal purposes in different countries throughout the world. Earlier in research, it was reported that the elevated cholesterol concentration was s...
GC-MS ANALYSIS, PHYTOCHEMICALS AND IN-VITRO ANTIOXIDANT PROPERTIES OF ROOT EXTRACTS OF PHLOGACANTHUS THYRSIFLORUS NEES., WESTERN ASSAM, INDIA
The Phlogacanthus thyrsiflorus roots have been used by the tribal population of western Assam to treat the hepatic disorder. The present study focuses on phytochemical screening, GC-MS analysis and in-vitro antioxidant activities using different extracts. Plant total phenolics, flavonoids, reducing power assay and antioxidant activity was evaluated. DPPH, FRAP, ABTS, Metal chelating activity,...