Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
PHARMACOVIGILANCE SIGNALS DETECTION: BENZODIAZEPINES AND SKIN AND SUBCUTANEOUS TISSUE DISORDERS
Pharmacovigilance compiles and analyzes spontaneous adverse drug reactions (ADRs) notifications reports on pharmacovigilance databases. Benzodiazepines have been related to skin and subcutaneous tissue disorders ADRs (SSTD-ADRs); tetrazepam was withdrawn in 2013 because of these ADRs. We intended to locate possible associations between cutaneous ADRs and benzodiazepines marketed in USA; for that, ...
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MICROARRAY BASED IDENTIFICATION REVEALS ARTERIAL ANGIOTENSIN SYSTEM EXPRESSION IN HUMAN
Purpose: We studied by microarray analysis the tissue angiotensin system organization. We elucidated the expression of chymase, cathepsins D, G and angiotensin-converting enzyme (ACE), potentially involved in intraparietal angiotensin II formation and atheroma. Methods: mRNA gene expression was measured by an Affymetrix Gene Chip Human Gene 1.0 ST arrays (Affymetrix, Santa Clara, CA, USA) using RN...
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PREVENTIVE EFFECT OF HELIX ASPERSA CRUDE EXTRACT AGAINST CHEMO-INDUCED COLONIC DAMAGES IN RATS
The present work aimed to explore in vivo the effect of Helix Aspersa Crude Extract (HACE) on the chemo-induced damages occurred in rat colon specially on the histology of the crypts foci in liberkhun glands. The toxicity of HACE was evaluated with different HACE concentrations. With the concentration of 160 mg, animals showed the best gain weight, stayed normal and all animals survived. Therefore...
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IMMUNOHISTOCHEMICAL DETECTION OF CASPASE 8 EXPRESSION AND APOPTOTIC INDEX ACTIVITIES OF CALVATIA CRANIIFORMIS CRUDE EXTRACT IN BALB/C MICE INOCULATED WITH H22 CELLS
Objectives: To identify Immunomodulatory, apoptosis induction and anticancer activities of aqueous and alcoholic extracts of Calvatia craniiformis regarding the size of tumor mass and immunohistochemical detection of caspase 8 expressions and apoptotic index in mice inoculated with H22 mouse hepatocellular carcinoma cells as therapeutic experimental system for human hepatocellular carcinom...
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ENUMERATION OF ORGANCHLORINE, ORGANOPHOSPHATE AND SYNTHETIC PYRETHROIDS IN BEANS GROWN IN FIVE DISTRICTS OF KARNATAKA
Pesticide residues in food and crops are a direct result of application of pesticides to crops growing in the field. Large quantities of pesticides are being used to control various pests, which normally infest the economically important plants. Beans- grown across the country and provides an important source of income for the small and marginal farmers. Bean growing in five districts of Karnataka...
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PERFORMANCE OF ASSOCIATION RULES FOR DENGUE VIRUS TYPE1 AMINO ACIDS USING AN INTEGRATION OF TRANSACTION REDUCTION AND RANDOM SAMPLING (TRRS) ALGORITHM
Association rule mining is the recent research area in data mining. Frequent Itemset Mining techniques is one of the prominent techniques in pattern mining. In this system frequent itemset mining is used to find the frequent amino acids patterns in Dengue Virus Type1 data set. This system uses an integration of Transaction Reduction and Random Sampling (TRRS) approach to identify the frequent patt...
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IN VITRO CYTOTOXICITY EVALUATION OF ESCITALOPRAM LOADED NANOPARTICLES AFTER EXPOSURE TO NEUROBLASTOMA CELL LINES
The aim of the present studies is to evaluate the cytotoxic effects of newly formulated polymeric nanoparticles (ETP NP’s) of Escitalopram oxalate (ETP) on NB41A3 cell lines. They were made by ionic gelation method with particle size range between 60 - 115nm, showing spherical morphology. Moreover, zeta potential of the same was recorded as -1.89 ± 0.052 mV and its permeability release showed 9...
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PREVALENCE AND CORRELATION OF VIRAL INFECTION (HEPATITIS B OR/AND HEPATITIS C) AMONG HYPERTENSIVE AND DIABETIC PATIENTS IN MALAYSIA AND INDONESIA WHO UNDERWENT HEMODIALYSIS
Background: Increase prevalence of viral infection such as hepatitis B or/and hepatitis C are followed by high incidence of mortality among hemodialysis patients. Objective: To determine prevalence and correlation of viral infection (Hepatitis B or/and Hepatitis C) among Hemodialysis Patients that died for the last five years in Indonesia and Malaysia in relation to gender, age, causes, and countr...
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EFFLUX PUMP INHIBITORS: ENHANCE THERAPY AND CAUTERIZE TUBERCULOSIS
The requirement of drug resistance regularly to plague Tuberculosis control, with vast increase in the spreading of MDR-TB. It can act as a gateway to XDR-TB and then emphasis on the urgency for new drug development and optimal treatment option for Tuberculosis therapy. In this study, we assess the recommending for using Rifabutin (RFB) instead of rifampicin (RIF). The objective of this study and ...
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β-CYFLUTHRIN-INDUCED IMPAIRMENT IN NEUROTRANSMITTERS, TESTICULAR FUNCTION AND GENE EXPERISSIONS OF MALE RATS: THE PROTECTIVE ROLE OF OMEGA-3
The present study was designed to evaluate the protective effect of omega-3 against β-cyfluthrin (β-cyf)-induced neurotransmitters’ impairment, oxidative damage, testicular toxicity and genotoxicity. Adult male Wistar rats were divided equally into four groups: Group (I): Control, Group (II): β-cyf (5 mg/kg body weight/day), Group (III): omega-3 (400 mg/kg body weight/da y) + β-cyf (5 mg/kg ...
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