Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
HYDROTROPHY: NOVEL SOLUBILITY ENHANCEMENT TECHNIQUE: A REVIEW
Drug discovery and development plays a major role in the world and serves mankind. The major criteria to be considered and given importance in drug development is the solubility of a drug. Among all newly discovered chemical entities, about 40% of drugs fail to reach the market due to their poor aqueous solubility or lipophilicity. Poor solubility is not only a problem for formulation development ...
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STUDY OF FORCED DEGRADATION BEHAVIOUR OF A NOVEL PROTEASOME-INHIBITING ANTICANCER DRUG BY LC-MS AND DEVELOPMENT OF A VALIDATED STABILITY-INDICATING ASSAY METHOD
In the present study, comprehensive stress testing of Carfilzomib, a newly approved proteasome-inhibiting anticancer drug was carried out according to ICH guideline Q1A (R2). The drug was subjected to acid (0.1N HCl), neutral and alkaline (0.1N NaOH) hydrolytic conditions at 70 ºC, as well as to oxidative decomposition at room temperature. Photolysis was carried out in 0.1N HCl, water and 0.1N Na...
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OVERVIEW OF FAVIPIRAVIR AND REMDESIVIR TREATMENT FOR COVID-19
The current coronavirus disease 2019 (COVID-19) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in the wholesale market in Wuhan, China in the last months of 2019 and spread to almost all countries of the world. Although several vaccines have already been developed in different countries of the world, there is currently no specific treatment for COVID-19. So...
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FORMULATION AND EVALUATION OF SELF EMULSIFYING DRUG DELIVERY SYSTEM (SEDDS) OF IBUPROFEN
Aim of present investigation was to develop self emulsifying drug delivery system of ibuprofen to enhance solubility, dissolution rate which may improve therapeutic performance and drug loading capacity so as to develop alternative to traditional oral formulations to improve bioavailability. In this study Labrafac, Tween 80 and PEG 200 were selected as oil, surfactant and co-surfactant respectivel...
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REVIEW ON THE CONCEPT OF IMMUNOMODULATION IN AYURVEDA WITH SPECIAL EMPHASIS ON PRAKARA YOGA
An immunomodulator can be defined as a substance, which can influence any constituent or function of the immune system in a specific or nonspecific manner including both innate or adaptive arms of the immune response. The Ayurvedic system of medicine details the concept of immunomodulation by the term Rasayana. The use of herbs for improving the overall resistance of body against common infections...
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1, 3, 4-OXADIAZOLE NUCLEUS WITH VERSATILE PHARMACOLOGICAL APPLICATIONS: A REVIEW
Oxadiazole is a heterocyclic compound containing an oxygen atom and two nitrogen atoms in a five membered ring. It is derived from furan by substitution of two methylene groups (=CH) with two pyridine type nitrogens (-N=). It is also termed as a lead compound for designing the potent bioactive agents. It has been reported as a surrogate of carboxylic acid and an important synthons in organic che...
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NANOROBOTS: A REVIEW
Nanomedicine offers the prospect of powerful new tools for the treatment of human diseases and the improvement of human biological systems. Nanomedicine is the process of diagnosing, treating, and preventing disease and traumatic injury, of relieving pain, and of preserving and improving human health, using molecular tools and molecular knowledge of the human body. Nanomedicine's nanorobots are so...
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IN VITRO ANTICANCER ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF BACOPA MONNIERI (L.) WETTST.
Plants have played a significant role in the treatment of cancer and infectious diseases for the last many decades. Natural products have been rediscovered as important tools for drug development despite advances in combinatorial chemistry. Bacopa monnieri (L.) Wettst. (Scrophulariaceae) is a herbaceous plant traditionally used from time immemorial in Ayurvedic and folklore medicines. The various ...
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VINPOCETINE: A SMART DRUG AND A SMART NUTRIENT: A REVIEW
Vinpocetine, a semisynthetic derivative alkaloid of Vincamine, an extract from the periwinkle (plant) Vinca minor is the first full-fledged nootropic (a supplement positively affecting the mind). Vinpocetine is safe and non-toxic with an amazing array of functional and structural benefits for improved health. Vinpocetine appears to improve a person's ability to acquire new memories and to restore ...
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BIOCHEMICAL AND ANTIMICROBIAL STUDY OF BOERHAVIA ERECTA AND CHROMOLAENA ODORATA (L.) KING & ROBINSON
Purpose: The present study was designed to evaluate the phytochemical, biochemical and antimicrobial activity of leaf extracts of Boerhavia erecta and Chromolaena odorata. Methods: The leaves of Boerhavia erecta and Chromolaena odorata were washed with tap water followed by distilled water. The cleaned leaves were shade dried and then made to fine powder by using homogenizer. Ab...
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