Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 5.2 | 2.73 | 0.64 |
FORMULATION AND EVALUATION OF ORAL DISPERSIBLE TABLETS OF CINNARIZINE USING DIRECT COMPRESSION TECHNIQUE
In the present work, oral dispersible tablets of cinnarizine were prepared by direct compression method with a view to enhance patient’s compliance. Five different superdisintegrants viz. crosspovidone, sodium starch glycolate, crosscarmellose sodium and low-substituted hydroxypropylcellulose (L-HPC) and pregelatinized starch were used along with microcrystalline cellulose (Avicel PH 102) and di...
6918
1977
DENDRIMERS: NOVEL DRUG NANOCARRIERS
Dendrimers are unique class of the polymer which is characterized by its extensively branched 3D structure that provides a high degree of surface functionality and versatility. Many drugs used in various therapies are facing difficulties like toxicity or nonspecific targeting. New delivery technologies could help to overcome this challenge. Nanostructures with uniform and well-defined particle siz...
3694
1231
COMPATIBILITY AND STABILITY STUDIES OF AMPICILLIN TRIHYDRATE AND PIPERINE MIXTURE
Ampicillin is used to treat variety of Bacterial infections in Humans. Piperine, an alkaloid from Piper species is reported to enhance oral bioavailability of co-administered drugs. The present study was aimed to include to Piperine (bioenhancer) as a formulation additive in oral formulations of Ampicillin Trihydrate. So, a Physical mixture of Ampicillin Trihydrate and Piperine (1:1) was tested ...
5413
1511
ANTIBACTERIAL ACTIVITY OF RICINUS COMMUNIS LEAF EXTRACT
Based on the scope given by traditional knowledge, present study was conducted. The aim of the present study was to evaluate the antibacterial activity of castor (Ricinus communis, Family: Euphorbiaceae) leaf extract using five bacteria; two Gram-positive bacteria (Bacillus subtilis and Staphylococcus aureus) and three Gram-negative bacteria (Escherichia coli, Proteus vulgaris, Pseudomonas aerug...
10828
2281
UV-VISIBLE SPECTRAL ANALYSIS OF BORIC ACID IN DIFFERENT SOLVENTS: A CASE STUDY
Boric acid is one of the widely used inorganic compound in pharmaceutical industry. We find its utilization as an antiseptic, in eye wash preparations, as an insecticidal, as a buffering agent etc. In this present work, a comparative study of the UV-Vis spectras of the boric acid solution in different solvents have been done. A variety of solvents like water, ethanol, methanol, glacial acetic ac...
10308
3654
TRANSDERMAL DRUG DELIVERY SYSTEM (TDDS): AN OVERVIEW
The transdermal route of drug delivery has attracted researchers due to many biomedical advantages associated with it. However, excellent impervious nature of skin is the greatest challenge that has to be overcome for successfully delivering drug molecules to the systemic circulation by this route. This review describes enhancement techniques based on drug/vehicle optimization such as physical and...
8469
1987
ANTI-INFLAMMATORY, ANTI-ARTHRITIC AND ANALGESIC ACTIVITY OF THE ALCOHOLIC EXTRACT OF THE PLANT URGINEA INDICA KUNTH.
This study was designed to present the observation of the pharmacological properties to the bulb of the plant. The extract of the bulb of Urginea indica Kunth were collected by using of alcoholic extraction. The anti-inflammatory action of the alcoholic Extract of the bulb of the plant Urginea indica was evaluated in rats (female) against carrageenan induced edema i.e., using plethysmographic meth...
3671
1309
FLUORESCENCE ANALYSIS OF TWO MEDICINAL PLANTS – PSIDIUM GUAJAVA L AND CITRUS AURANTIUM
The plants used for the present study viz., Psidium guajava L and Citrus aurantium belong to the family Myrtaceae and Rutaceae respectively. Guava is native to tropical America. The young leaves are used as tonic in digestive disorders. Bitter orange is native of South Eastern Asia; grow in Tamil Nadu, Karnataka, Maharashtra, Punjab and Uttar Pradesh. It is a rich source of provitamin A. The prese...
11967
2725
STUDIES OF PRELIMINARY PHYTOCHEMICAL SCREENING, MEMBRANE STABILIZING ACTIVITY, THROMBOLYTIC ACTIVITY AND IN-VITRO ANTIOXIDANT ACTIVITY OF LEAF EXTRACT OF CITRUS HYSTRIX
In this present study, the leaf extracts of Citrus hystrix were subjected to a comparative evaluation of preliminary phytochemical screening, membrane stabilizing activity, thrombolytic activity and In-vitro antioxidant activity. The thrombolytic and membrane stabilizing activities were assessed by using human erythrocyte and the results were compared with standard streptokinase (SK) and standard ...
4047
1606
PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL ACTIVITY OF GYMNEMA SYLVESTRE R.BR. EX SCHULT.
The present investigation deals with preliminary phytochemical analysis and in vitro antibacterial potentials of different solvent extracts of Gymnema sylvestre were demonstrated. The phytochemical tests of the extracts have revealed the presence of alkaloids, flavonoids, phenols, tannins, terpenoids carbohydrate, tannin, and saponin. Five gram-positive (Bacillus cereus, Bacillus subtilis, Strepto...
5524
1468