Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
TRYPSIN AND PROTEIN DENATURATION INHIBITORY ACTIVITY OF DIFFERENT FRACTIONATION AND ISOLATED COMPOUND OF LEAF AND ROOT OF JUSTICIA GENDARUSSA
Rheumatoid arthritis is a major ailment among autoimmune disorders. A large number of herbal extracts were used for the treatment of various types of rheumatoid disorder. The leaf and root of Justicia gendarussa belonging to Acanthaceae family, commonly known as Nilinirgundi is traditionally used for chronic rheumatism. The present study deals with in-vitro anti-arthritic activity in pharmacologic...
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PERMEATION STUDIES OF PIOGLITAZONE HCL FROM FICUS CARICA FRUIT MUCILAGE MATRIX TRANSDERMAL PATCHES
The main purpose of the present study was to develop matrix moderated transdermal patches of Pioglitazone HCl using various ratios of Ficus carica fruit mucilage. Physical parameters such as moisture content, moisture uptake, tensile strength, elongation and folding endurance were evaluated. The matrix type transdermal patches were prepared using Pioglitazone HCl with Ficus carica fruit mucilage b...
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COMPARISON OF VARIOUS NATURAL SUPERDISINTEGRANTS IN THE FORMULATION OF FAST DISSOLVING CARVEDILOL TABLET
In the present investigation, fast dissolving tablets of Carvedilol were formulated by using various natural superdisintegrant like Plantago ovata, Lepidium sativum, Fenugreek and Guar gum. A Direct compression method was used to prepare fast dissolving tablets containing Carvedilol as a model drug using natural superdisintegrants. Prepared formulations were evaluated for Precompression parameters...
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A NOVEL APPROACH IN GASTRO RETENTIVE DRUG DELIVERY SYSTEM: FLOATING DRUG DELIVERY SYSTEM
The task of achieving efficient delivery of drugs that have poor bioavailability or narrow absorption windows have plagued the pharmaceutically industry for decades. Thus, much research has been dedicated to the development of novel polymeric-based gastro retentive drug delivery technologies that may optimize the bioavailability and subsequent therapeutic efficacy of such drugs. Several technical ...
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NON-PROLIFERATIVE ACTIVITY OF SAPONINS ISOLATED FROM THE LEAVES OF GYMNEMA SYLVESTRE AND ECLIPTA PROSTRATA ON HEPG2 CELLS- IN VITRO STUDY
The non-proliferative activity of isolated saponins, gymnemagenol (C30H50O4) from Gymnema sylvestre and dasyscyphin C (C28H40O8) from Eclipta prostrata leaves were tested under on HepG2 cells under in vitro conditions. Both gymnemagenol and dasyscyphin C exhibited non-proliferative activity on HepG2 cells at 24 h with the IC50 value of 18.5 and 23.5μg/ml respectively. 5-Fluorouracil (5FU) a posit...
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HYPHENATED TECHNIQUE- A BOON TO ANALYTICAL WORLD
Traditional analytical approaches including HPLC (High-Performance Liquid Chromatograph), GC (Gas Chromatograph), UV (Ultraviolet) detection, etc., have become insufficient to effectively handle the growing number of challenges in analyses of species- specificity and sensitivity. Modern analytical technique referred to as hyphenated techniques, originate from the traditional use of molecule or ele...
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EVALUATION OF ANALGESIC ACTIVITY OF MOMORDICA DIOICA ROXB. WILLD FRUIT PULP
In the present study Momordica dioica Roxb willd (Cucurbitaceae) fruit pulp was successively extracted with petroleum ether, ethyl acetate and methanol. All extracts were vacuum dried to yield the respective extracts. All extracts were evaluated by non-narcotic models like acetic acid induced writhing syndrome test and narcotic models like hot plate for its analgesic activity in doses of 50 mg/kg ...
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SIMULTANEOUS ESTIMATION OF AMITRIPTYLINE HYDROCHLORIDE AND PERPHENAZINE BY ABSORPTION RATIO (Q- ANALYSIS) UV SPECTROPHOTOMETRIC METHOD IN COMBINED TABLET DOSAGE FORM
The simple, accurate and precise absorption ratio method has been developed for the simultaneous estimation of amitriptyline HCl and perphenazine in combined tablet dosage form. The λmax of amitriptyline HCl and perphenazine were found to be 240.0 nm and 258.0 nm respectively. For the estimation by Q-analysis method, the λmax those selected were 240.0 nm and an isoabsorptive point for both the d...
5758
2206
ASSESSMENT OF DETERMINANTS OF INDUCED ABORTION AMONG CHILD BEARING AGE WOMEN ATTENDING MATERNAL AND CHILD HEALTH CLINIC IN MEKELLE TOWN, TIGRAY, ETHIOPIA: A CROSS SECTIONAL STUDY
Background: Abortion is the termination of a pregnancy by the expulsion of a fetus or embryo from the uterus. Induced abortion is usually defined as deliberate pregnancy termination prior to 20 weeks (for developed countries) and 28weeks (for developing countries) gestation. Describing the determinants of induced abortions contributes for long lasting reduction of induced abortion. Objective: ...
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VISIBLE SPECTROPHOTOMETRIC DETERMINATION OF TELMISARTAN FROM URINE
The proposed method is new, simple, sensitive, reproducible, economical, accurate and precise and can be successfully applied in estimation of Telmisartan (Telmi) from urine. This method can find applications in clinical studies and therapeutic drug monitoring. This method of colorimetric estimation of telmisartan from urine is based on the formation of yellow colored chromogen when it is reacted ...
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