Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
ANALGESIC AND ANTI-INFLAMMATORY EFFECTS OF OCIMUM SANCTUM (LINN) IN LABORATORY ANIMALS
Ocimum sanctum (L.) is popularly used as herbal remedy for various ailments. But the scientific basis for its medicinal use especially in pain and inflammation remains unknown. Therefore, the present study was aimed to investigate the analgesic and anti-inflammatory effects of the leaves of Ocimum sanctum in laboratory animals. The ethanol extract of the leaves of O. sanctum was used to investigat...
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EFFECT OF MAST CELL STABILIZER, KETOTIFEN ON STREPTOZOTOCIN INDUCED EXPERIMENTAL DIABETIC NEPHROPATHY IN RATS
Background: Infiltration and degranulation of mast cells has been noted to occur in renal diseases and are reported to play a key role in inflammation. Degranulation of mast cells releases various inflammatory mediators such as cytokines, endothelins, growth factors and proteolytic enzymes. Ketotifen has been reported as stabilizer of mast cells. Thus, the present study is designed to investigate ...
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1055
SYNTHESIS, EXPERIMENTAL STUDIES OF THE ANTIMICROBIAL POTENTIAL OF SOME NOVEL 1, 5- BENZO THIAZEPINE DERIVATIVES
Optically active 1, 5- benzothiazepines belong to the well known benzothiazepine type substances. Some of them possess important bioactivities. In this article, optically active 2, 3-dihydro-1, 5-benzothiazepine derivatives are synthesized by the reaction of new α-β unsaturated carbonyl compounds with 2-aminothiophenol under mild conditions in the presence of silver sulphate in acetonitrile in s...
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1264
INVESTIGATION ON REGIONAL VARIATION IN TOTAL PHENOLIC, ALKALOID CONTENT AND IN-VITRO ANTIOXIDANT ACTIVITY OF LEUCAS ASPERA
In this study, we investigated and compared the total phenolic, alkaloid content and in-vitro antioxidant activity of Leucas aspera collected from four different regions; Tirupathi (Southern zone), Lam (Krishna river region), Jagityala (Northern Telangana) and Hyderabad (Southern Telangana) of Andhra Pradesh, India. Quantitative regional variation was observed in total phenolic content, and alka...
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1271
STUDIES ON ANTIULCER ACTIVITY OF ESSENTIAL OIL OF CALAMINTHA OFFICINALIS MOENCH.
The present study was undertaken to determine the anti-ulcer potential of Calamintha officinalis Moench, a standardized oil of Calamintha officinalis Moench, commonly known as Calamint. Effect of various doses (0.4ml/kg and 0.8ml/kg,) of Calamintha officinalis Moench. oil was studied on gastric ulcers in pylorus ligation, Diclofenac sodium induced gastric mucosal injury in rats. Anti-ulcer activit...
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DULOXETINE HYDROCHLORIDE DELAYED RELEASE PELLETS PREPARED BY SUSPENSION LAYER METHOD
The aim of present study is to develop a delayed release pellets dosage form of duloxetine hydrochloride with a suitable polymer by using suspension layered method. Drug loaded nuclei was prepared using suspension layered technique in a Fluidized Bed Processor, the nuclei was coated with an acid resistant acrylic polymer (Eudragit L30-D55) and compared acid resistant properties with HPMC phthalate...
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PHARMACOGNOSTICAL INVESTIGATIONS ON IPOMOEA AQUATICA FORSK.
Plants are a great source of medicines, which are useful in the treatment of various diseases. Ipomoea aquatica Forsk of family Convolvulaceae commonly known as Kalmisag or Nalanibhaji is being used as a green leafy vegetable and have great medicinal value in Indian medicine. It is used in Unani System of Medicine as carminative, lessens inflammation, useful in fever, jaundice, biliousness, bronch...
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FORMULATION OF GASTRORETENTIVE DRUG DELIVERY SYSTEM (FLOATING TABLETS) OF NIFEDIPINE
Among novel drug delivery systems, rate controlled oral drug delivery system forms an important area. Recent technological and scientific research has been devoted to the development of rate controlled drug delivery systems to overcome physiological adversities such as short gastric residence times and unpredictable gastric emptying times. Several approaches are currently utilized in the prolongat...
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2044
HYPOGLYCEMIC EFFECT OF ACALYPHA INDICA LINN. PLANT EXTRACTS ON STREPTOZOTOCIN INDUCED DIABETES IN RAT
The plant Acalypha indica Linn. is commonly known as Indian Acalypha and it belongs to the family Euphorbiaceae, found in all parts of the tropics. This herbs found in fields and wastes places throughout the hotter parts of the world. The plant has wide uses in the traditional medicines of various countries and reportedly possesses diuretic, purgative and anthelmintic properties, b...
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1216
SYNTHESIS AND IN- VITRO ANTIOXIDANT ACTIVITY OF SOME NEW 2, 5-DISUBSTITUTED-1, 3, 4-OXADIAZOLES CONTAINING FURAN MOIETY
A series of five membered heterocyclics was synthesized by the reaction between refluxing 2 - furoic acid with ethanol and conc. H2SO4. The obtained ester (2) with hydrazine hydrate and ethanol was refluxed to give hydrazides (3). Reaction of hydrazides (3) with different aromatic acids using phosphorousoxy trichloride (POCl3) lead to the formation of 2-Aryl -5-furyl -1, 3, 4-oxadiazoles [DM (1-...
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