Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
SYNTHESIS, CHARACTERISATION AND BIOLOGICAL EVALUATION OF NOVEL OXADIAZOLE DERIVATIVES
New 5- phenyl- 1, 3, 4- oxadiazole- 2- thiol derivative was synthesized by the ring closure reactions of benzohydrazides with carbon disulphide in presence of ethanolic KOH followed by substitution with secondary amines at 2nd position. All the newly synthesized compounds were characterized by IR, NMR and LC-MASS spectral data. Most of them were tested for their anti-inflammatory and antibacte...
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TOTAL ANTIOXIDANT CAPACITY IN AQUEOUS EXTRACTS OF SOME COMMON FRUITS
The present study was aimed to evaluate total antioxidant capacities of eleven different commonly consumed aqueous fruit extracts viz. Ananas comosus, Artocarpus heterophyllus, Carica papaya, Citrullus vulgaris, Citrus sinensis, Malus domestica, Manilkara zapota, Musa paradisiaca, Phyllanthus emblica, Psidium guajava and Pyrus communis. The total antioxidant capacity was assessed using phosphomoly...
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ANTIOXIDANT POTENTIAL FRACTIONATION FROM METHANOL EXTRACT OF AERIAL PARTS OF RUELLIA PROSTRATA POIR (ACANTHACEAE)
Aerial parts of Ruellia prostrata were subjected to extraction and further fractionation to obtain antioxidant rich fraction. Different concentrations of methanolic extract and its n-butanolic fraction were subjected to antioxidant assay by DPPH method, Nitric oxide scavenging activity and reducing power assay. The fractions showed dose dependent free radical scavenging property in all the models....
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PHYTOCHEMICAL STUDIES OF MELIA AZADIRACHTA & MURRAYA KOEINGI
Quercetin is the most abundant natural flavonoid, present in medicinal plants. Quercetin is of interest because of its pharmacological function. Quantification of quercetin from the dried leaves of Melia azadirachta and Murraya koiengi was carried out based on chromatographic separation. Sensitive, simple, and accurate high-performance liquid chromatographic method has been established for detecti...
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PHYTOCHEMICAL ANALYSIS AND ANTIFUNGAL ACTIVITY OF MOSS BRYUM CELLULARE AGAINST SOME PHYTOPATHOGENIC FUNGI
Bryophytes possess a pool of bioactive compounds with pharmacological activity. These plants have widely been used as medicinal plants since ancient times and are not infected by bacteria and fungi as they use chemical weapons in the form of secondary metabolites. In order to evaluate the antifungal activity of aqueous crude extract of Bryum cellulare (a moss) against the test fungi Curvularia lun...
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ISOLATION CHEMICAL CHARACTERIZATION AND HYPOGLYCEMIC ACTIVITY OF ALANGIUM SALVIIFOLIUM WANG BARK IN ALLOXAN INDUCED HYPERGLYCEMIC RATS
Aim of the present study was to isolate and characterize the biochemical principle and investigate the hypoglycemic activity of bark of Alangium salviifolium Wang in Alloxan induced hyperglycemic rats. The bark of Alangium salviifolium barks were collected and dried in shade and subjected to extraction with petroleum ether, Chloroform and methanol. Each extracts were subjected to preliminary phyto...
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A COMPARATIVE STUDY OF MICHELIA CHAMPACA LINN. FLOWER AND LEAVES FOR ANTI – ULCER ACTIVITY
An Ulcer is a sore which means an open painful wound in mucous membranes or mucosal linings of the body. Gastro intestinal ulcers frequently occur in the stomach and duodenum where acid and pepsin activity is greatest. Peptic ulcer disease can be prevented by strengthening the cytoprotection, the defensive mechanism of gastric mucosa, rather than attenuating factor of aggression causing ulceration...
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SYNTHESIS & ANTI- MICROBIAL EVALUATION OF N-(2-(4-SUBSTITUTED PHENYL)-4-OXOTHIAZOLIDIN-3-YL) ISONICOTINAMIDE DERIVATIVES
A new series N-(2-(4-substituted Phenyl)-4-oxothiazolidin-3-yl)isonicotin- amide of derivatives were synthesized by the reaction of Schiff base (isoniazid and substituted benzaldehyde) with mercaptoacetic acid. The chemical structures of the synthesized compounds were confirmed by means of IR, 1H-NMR. The synthesized compounds showed good antibacterial activity against Staphylococcus aureus and Es...
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DETERMINATION OF RIZATRIPTAN IN BULK AND ITS TABLET DOSAGE FORMS BY UV SPECTROSCOPIC METHOD.
Rizatriptan is a selective 5-HT1B/1D agonist which is used in the treatment of migraine headaches. Zero order spectroscopic method has been developed for the determination of rizatriptan. Rizatriptan in its 0.1 N HCl solutions was determined at the wavelength ranges of 220–400 nm by the spectroscopic method. Rizatriptan showed an absorption peak at 226 nm. Linearity ranges were found as 1-5 µg/...
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GC-MS STUDY OF IXORA PAVETTA VAHL.
Ixora pavetta Vahl. is a small tree, traditionally used for the treatment of diarrhoea, dysentery, urinary disorders, leucorrhoea, veneral diseases and sedative. The flowers of the plant were extracted with ethanol by cold percolation method. The presence of the compounds in the extract was analyzed by GC-MS technique. The parameters of mass spectral analysis viz. retention time and characteristic...
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