Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
IN-SILICO ADMET PREDICTION OF PHYTOCHEMICALS IN CAMELLIA SINENSIS AND CITRUS SINENSIS
Camellia sinensis and Citrus sinensis are treasuries of medicinal properties. The compounds present in these plants can deliver potential therapeutic drug. Most of the drugs in clinical development fail to commercialize because of poor ADME and toxicity properties. The main aim of the study is pharmacokinetic investigation and toxicity property, the most causes of high attrition rates in drug de...
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PUNICA GRANATUM ATTENUATES SCIATIC NERVE LIGATION INDUCED-NEUROPATHIC PAIN
The study has been designed to investigate the effect of aqueous extract of rind of Punica granatum in sciatic nerve ligation induced-neuropathic pain in rats. Surgical procedure was performed with sciatic nerve ligation to develop neuropathic pain in rats. The development of neuropathic pain was assessed by employing behaviour parameters such as hyperalgesia and allodynia. Further, the functional...
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GC-MS ANALYSIS OF CHLOROFORM EXTRACT OF CLEOME BURMANNI W. AND A. (CLEOMACEAE)
The present study was carried out to determine the presence of phytocomponents in the aerial parts of Cleome burmanni using Gas Chromatography- Mass Spectrometry (GC-MS) analysis. The mass spectrum of the crude chloroform extract was compared with the available library sources (NIST08 LIB, WILEY8 LIB). Sixteen components were identified. Sterols, terpenoids and hydrocarbons were the most prominent...
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THREE GENERATIONS: PIMARY, SECONDARY AND TERTIARY GENERATIONS OF TRANSDERMAL DRUG DELIVERY SYSTEMS: A REVIEW
From this article, we get the knowledge about the transdermal patch, transdermal drug delivery system and anatomy of the skin. Now-a-days transdermal drug delivery, system is widely used in much disease. So, this article gives the knowledge about pre transdermal system, post transdermal drug delivery system and future of transdermal drug delivery systems and examines the benefits and limitations o...
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DENDRIMERS – A NEW CLASS OF POLYMERS
Dendrimers are highly branched and reactive three-dimensional macromolecules, with all bonds emanating from a central core. Compared with traditional linear polymers, Dendrimers have much more accurately controlled structures, with a globular shape, a single molecular weight rather than a distribution of molecular weights, and a large number of controllable ‘peripheral’ functionalities. All th...
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SYNTHESIS, CHARACTERIZATION AND PHYSICOCHEMICAL STUDIES OF Ni(II) AND Cu(II) COMPLEXES WITH SOME NITROGEN- OXYGEN AND NITROGEN SULPHUR DONOR LIGANDS
Ni(II) and Cu(II) complexes of Schiff base thiosemicarbazones (L1) and semicarbazones (L2) derived from pyrrole-2-carboxaldehyde. These complexes are characterized by elemental analysis, molar conductance measurements, magnetic suscepectibility measurements, mass, IR, electronic and EPR spectral studies. The molar conductance measurements of the complexes in DMSO determine the non-electrolytes and...
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VALIDATED RP – HPLC METHOD FOR THE QUANTIFICATION OF ANDROGRAPHOLIDE IN TOXIROAK PREMIX, A POLYHERBAL MYCOTOXIN INHIBITOR
A new simple, rapid, precise, accurate and specific RP-HPLC method was developed to carry out the quantification of Andrographolide in the formulation vis a vis its standardization to ensure the batch to batch consistency in mycotoxin inhibition activity of the polyherbal formulation Toxiroak premix. An optimal condition of separation and detection were achieved on a Phenomenex luna C18 column (25...
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COMPARATIVE ANALGESIC ACTIVITY OF SELECTED MEDICINAL PLANTS FROM INDIAN ORIGIN
Synthetic analgesic drugs have major side effects like gastritis, gastric ulcer, kidney disorders and cardiac arrhythmias. So, use of natural or herbal analgesics is an important and growing part of the pain-control and new discoveries are made practically every year. Many of these drugs commit the side effects like Morphine is responsible do work against heavy sedation and may elevate mood in dis...
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PHYSICOCHEMICAL, MECHANICAL & FILM FORMING STUDIES OF NOVEL BIOMATERIAL
Gum Dammar is a natural resinous material of plant Shorea javanica, family–Dipterocarpaceae. In the present investigation Dammar gum (DG) and alcohol soluble fraction of Dammar gum (DA) are evaluated for their physicochemical, mechanical and film forming characteristics. Films were produced by casting/solvent evaporation method from plasticizer free and plasticizer containing solutions. Films pr...
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OPTIMIZATION OF SOME CULTURE CONDITIONS FOR IMPROVED BIOMASS AND ANTIBIOTIC PRODUCTION BY STREPTOMYCES SPECTABILIS ISOLATED FROM SOIL
A Streptomyces strain was isolated from soil and was identified as Streptomyces spectabilis on the basis of 16 S rRNA gene sequencing. On screening for its ability to produce antimicrobial compounds, it was found to be active only against Gram positive bacteria. Attempts were made to optimize the culture conditions for the production of antimicrobial compounds. Basal medium supplemented with gluco...
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