Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
A NOVEL SPECTROFLUORIMETRIC METHOD FOR THE DETERMINATION OF MEMANTINE HYDROCLORIDE IN BULK AND PHARMACEUTICAL FORMULATION
The author selected and developed a new simple, sensitive and reproducible spectrofluorimetric method and validated for the determination of Memantine Hydrochloride in bulk as well as pharmaceutical formulations depending on condensation of Memantine hydrochloride with 1, 2 - Naphthoquinone -4- sulphonate (NQS) in an alkaline medium to become a product with orange color. The spectrofluorimetri...
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SYNTHESIS, SPECTRAL STUDIES AND ANTIMICROBIAL SCREENING OF SOME TRANSITION METAL COMPLEXES WITH SUBSTITUTED ACETOPHENONE THIOSEMICARBAZONE
Complexs of Fe, Cu and Zn have been prepared by reacting metal chloride\sulphate with p-hydroxyacetophenone thiosemicarbazone, p-fluoroacetophenone thiosemicarbazone, p-bromoacetophenone thiosemicarbazone as ligands and their complexes were screened for their IR, NMR, and antifungal and antibacterial studies. . Acetophenone thiosemicarbazone ligands were prepared by the reaction of substituted ace...
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1463
STUDY OF ENDOPHYTIC FUNGAL COMMUNITY OF MORINGA OLEIFERA FROM OMALUR REGION – SALEM
Endophytic fungi are ubiquitous in nature residing inside all the plant species contributing to their host plants by producing a plenty of substances that provide protection and survival value to the plant. Many researchers have proven that endophytes are a new and potential source of novel natural products for exploitation in modern medicine. This present study is undertaken to isolate and identi...
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DEVELOPMENT AND EVALUATION OF MICROBALLOONS OF PIOGLITAZONE HYDROCHLORIDE USING EUDRAGIT S-100
Various approaches have been used to retain the dosage form in the stomach as a way of increasing the gastric residence time (GRT), including floatation systems; high-density systems; mucoadhesive systems; magnetic systems; unfoldable, extendible, or swellable systems; and superporous hydrogel systems. The aim of this study was to prepare and evaluate floating microspheres of Pioglitazone hydrochl...
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THE EFFECT OF AVOCADO (PERSEA AMERICANA MILL.) LEAVES EXTRACT TOWARDS THE MOUSE’S BLOOD GLUCOSE DECREASE WITH THE GLUCOSE TOLERANCE METHOD
Decrease in blood glucose level test with the use of oral glucose tolerance method from Avocado leaves was carried out. Swiss Webster male mice were divided randomly into five groups. They were negative control, positive control (Glipizide 0.013 mg/20 g BW) and three test groups treated with dosage of avocado leaves ethanol extract 0.490 g/kg, 0.980 g/kg and 1.960 g /BW respectively. Experiment wa...
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ANTI-INFLAMMATORY ACTIVITY OF SAMADERA INDICA LEAVES BY MEMBRANE STABILIZATION
The present work aims at evaluating the anti-inflammatory activity of Samadera indica by HRBC membrane stabilization. The prevention of hypotonicity induced HRBC membrane lysis was taken as a measure of the anti-inflammatory activity. The anti-inflammatory activity of the crude ethanol extract, aqueous extract of leaves part of Samadera indica were compared to that of the standard drug diclofenac....
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ANTIMICROBIAL, CYTOTOXIC AND ANTIOXIDANT ACTIVITY OF THE EXUDATE OF CALOTROPIS GIGANTEA
Plant is one of the important source of drugs that’s why we have done this project work to find out some biological activities of the plant exudates of Calotropis gigantea where antimicrobial, cytotoxic and antioxidant activity were analyzed. To test of antimicrobial activity, disc diffusion method has been followed. The exudate of the plant has shown antimicrobial activity against four microorg...
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PASSION FRUIT: A FETCHED PASSION FOR DENTISTS
Objective: Dental caries is a common oral infection prevalent in developing countries. Streptococcus mutans, a commensal bacterium of the oral cavity, plays a major role in the etiology of caries and root canal infection. Sodium hypochlorite and Chlorhexidine are used in the prevention of caries and as root canal medicament though they cannot be used in combination. Study Design: Different conc...
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PHYTOCHEMICALS INVESTIGATION AND TLC ANALYSIS OF JASMINUM MULTIFLORUM LEAVES
Jasminum multiflorum belongs to the Oleaceae family. It is used as a traditional medicine from ancient times. It is a large evergreen twinner shrub found throughout India. Present study reports the phytochemical properties which have been carried out on the leaves extract using ethanol, methanol, ethyl acetate, acetone and n-hexane. The phytochemicals analysis show the presence of Phenols, Saponin...
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DEVELOPMENT AND VALIDATION OF UV METHOD OF TEMOZOLOMIDE IN BULK AND CAPSULE FORMULATION
An UV spectrophotometric method for the quantitative determination of Temozolomide (TMZ) in bulk and capsule was developed in present work. The parameters linearity, precision, accuracy, limit of detection and limit of quantitation were studied according to International Conference on Harmonization guidelines. UV spectroscopic determination wa...
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