Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
A VALIDATED RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF METRONIDAZOLE AND CIPROFLOXACIN HYDROCHLORIDE IN PHARMACEUTICAL DOSAGE FORM
A reversed-phase-liquid chromatographic (RP-HPLC) method was developed for the determination of Metronidazole (MTZ) and Ciprofloxacin HCl (CPX) in their bulk drug and marketed formulations. The separation was carried out using a mobile phase of 25mM Potassium dihydrgen phosphate buffer of pH 3.0 consisting of 0.15%v/v Triethylamine, 0.1% Phosphoric acid and Methanol in the ratio of( 60:40v/v). T...
7722
2330
CARDIO-VASCULAR ACTIVITY OF GYNURA PROCUMBENS MERR. LEAF EXTRACTS
Gynura procumbens has been known to be used as traditional medicine for treatment of kidney disease, rashes, fever and for hypertension. We report here the cardiovascular effects of the different ethanol (95%, 75%, 50%, 25% v/v) and water extracts using in vitro studies. Gynura procumbens leaves extract was prepared by maceration process. The cardiac effects (chronotropic and ionotropic) of each e...
6795
1998
LIQUISOLID TECHNIQUE FOR ENHANCEMENT OF DISSOLUTION PROPERTIES OF FENOFIBRATE
The in vitro dissolution property of slightly water soluble Fenofibrate (FN) was improved by exploring the potential of Liquisolid system (LS). The in vitro release pattern of LS compacts and directly compressed tablets were studied using USP-II apparatus. Different LS compacts were prepared using a mathematical model to calculate the required quantities of powder and liquid ingredients to produce...
4275
1932
DISSOLUTION ENHANCEMENT OF POORLY SOLUBLE CARBAMAZEPINE BY USING POLYMERIC SOLID DISPERSIONS
The purpose of this study was to improve the solubility of poorly soluble Carbamazepine by using solid dispersion technique utilizing common pharmaceutical polymers. The formulations were prepared with HPMC, PVP K30, and poloxamer 407 as polymers and methanol as solvent. The formulations were characterized by differential scanning calorimetry, Fourier transform infrared spectroscopy, in vitro diss...
6181
1947
REGULATORY ASPECTS OF TRADITIONAL MEDICINE: FOCUS TOWARDS UNANI COSMECEUTICAL PRODUCTS
The regulatory authorities are now focusing on the regulatory issues of traditional medicines under which Unani system of medicine falls. Today we are witnessing an increase in the use of traditional medicines throughout the world raising the questions as to how safe these preparations are. People are now bending towards the Unani system of medicine because of its safety, efficacy and lesser side ...
6321
2499
IN-VITRO ANTI-OBESITY ASSAY OF ALCOHOLIC AND AQUEOUS EXTRACTS OF CAMELLIA SINENSIS LEAVES
Obesity is one of the main public health problems in developed countries. It is considered to be a risk factor associated with the genesis or development of major chronic diseases, including cardiovascular disease, diabetes, and cancer. Many botanicals may provide safe, natural, and cost-effective alternatives to synthetic drugs. The results of this study show promise for the potential use of thes...
5030
1966
QUANTIFICATION OF GALLIC ACID AND ELLAGIC ACID IN ARJUNARISHTA BY VALIDTAED HPTLC DENSITOMETRY
Arjunarishta, also known as Parthadhyarishta, is a polyherbal hydro alcoholic formulation and is advised as a choice of remedy in cardiovascular disorders. A simple, precise and accurate HPTLC method has been established for the determination of quercetin and rutin in Arjunarishta–T and Arjunarishta-M prepared by traditional and modern methods respectively and also in its marketed formulation. T...
5582
2448
INHIBITION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A (HMG Co-A) REDUCTASE IN LIVER MICROSOMES BY MORINGA OLEIFERA L. POLYPHENOLS
Phytochemicals are the bioactive components present at micro level in our daily diet, especially the phenolic antioxidants, contribute to the prevention of cardiovascular and other degenerative diseases. Moringa oleifera (MO) leaves polyphenols effect on the activity of 3-hydroxy-3-methylglutaryl Coenzyme A (HMG CoA) reductase was studied using a spectrophotometric assay based on the stoichi...
5118
1886
EVALUATION OF JASMINUM GRANDIFLORUM FOR HEPATOPROTECTIVE ACTIVITY IN ISONIAZID INDUCED LIVER DAMAGE
Objectives: The study was designed to evaluate hepatoprotective effect of the ethanolic leaves extract of Jasminum grandiflorum (JG) in Isoniazid (INH) induced hepatotoxicity in wistar albino rats. Materials and methods: Mature leaves of JG were collected, authenticated and subjected to successive ethanolic extraction. Hepatic damage was induced in wistar rats by administering INH (54mg/kg, p.o...
4212
1824
DEVELOPMENT OF REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD AND ITS VALIDATION FOR ESTIMATION OF FORMOTEROL FUMARATE ROTA CAPS
A simple, rapid and reproducible HPLC method was developed and validated for the estimation of Formoterol Fumarate Rotacaps. Symmetry C8 (4.6×150mm, 5 µ) column, in isocratic mode with mobile phase containing Ammonium Acetate Buffer pH 5.0 and Acetonitrile (80:20) was used. The flow rate was 1.0 ml/min and the analyte was monitored at 254 nm. The retention time for Formoterol was about 4.6 mins....
4000
1632