Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR ESTIMATION OF DORZOLAMIDE HCl IN BULK AND PHARMACEUTICAL DOSAGE FORMS
Three Simple, precise, accurate and economical UV methods have been developed and validated for the quantitative estimation of Dorzolamide HCl in bulk and pharmaceutical dosage form. Dorzolamide HCl has the absorbance maxima at 253 nm in zero order spectra (Method A). In the first order derivative spectra, showed absorbance maxima at 238 nm (Method B) and in the second order derivative spectra, sh...
3744
1847
A PEDICULICIDAL ACTIVITY OF CLOVE OIL
The humans head lice are a nuisance for millions of people worldwide with high prevalence in children. Head lice have been treated by methods that include the physical removal of lice, various domestic treatments and conventional insecticides. None of these methods render complete protection and there is clear evidence for the evolution of resistance and cross-resistance to conventional insecticid...
9511
2042
ANTIBACTERIAL AND CYTOTOXIC ACTIVITY OF METHANOL EXTRACT OF SPILANTHES CALVA (DC) LEAVES
Methanol extract of leaves of Spilanthes calva (DC) was examined for their antimicrobial and cytotoxic properties. To determine antibacterial activities, the extract was tested against four gram-positive and six gram-negative bacteria at three concentrations (500, 800, 1000 µg disc-1) through disc diffusion method. The extract showed moderate antibacterial actions and that was increased by increa...
3981
1469
BIO-ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR OMEPRAZOLE USING LC-MS/MS
Analytical methods employed for the determination of drugs and metabolites in biological matrices such as urine, plasma and serum are essential throughout drug discovery and development. It is well-known that, analytical techniques are constantly undergoing change and improvements and each analytical method has its own characteristics which may vary from analyte to analyte at different condition...
6613
2301
STUDIES ON ANTIULCER ACTIVITY OF ESSENTIAL OIL OF CALAMINTHA OFFICINALIS MOENCH.
The present study was undertaken to determine the anti-ulcer potential of Calamintha officinalis Moench, a standardized oil of Calamintha officinalis Moench, commonly known as Calamint. Effect of various doses (0.4ml/kg and 0.8ml/kg,) of Calamintha officinalis Moench. oil was studied on gastric ulcers in pylorus ligation, Diclofenac sodium induced gastric mucosal injury in rats. Anti-ulcer activit...
3846
1728
PHARMACOGNOSTICAL, PHYTOCHEMICAL AND CARDIOPROTECTIVE ACTIVITY OF TAMARINDS INDICA LINN. BARK
Many herbal remedies have been employed in various medicine systems for the treatment and management of the different diseases. The Tamarinds indica commonly known as ‘imali’ has been recognized in different system of traditional medicines for the treatment of different diseases and aliments of human being. This review supports of all updated information on its pharmacognostical, pharmacologic...
5793
1920
POLYETHYLENE GLYCOL (PEG) SUPPORTED AMINO DENDRIMERS (DENDRITIC TRIBLOCK COPOLYMER) FOR DELIVERY OF METHOTREXATE (MTX)
Dendrimers are synthetic, highly branched, nanosized, monodisperse macromolecule which proving their applicability in different areas like diagnosis, drug delivery, gene delivery, molecular encapsulation etc. Due to their widespread applications, scientific community is continually engaged in developing newer dendrimers with advanced properties. In the present study, amino dendrimers are synthesiz...
3612
1442
HALOGENATED TRIAZINEDIONES BEHAVE AS ANTAGONISTS OF PKR1: IN VITRO AND IN VIVO PHARMACOLOGICAL CHARACTERIZATION
Different prokineticin receptor antagonists, based on the triazinedione scaffold, were synthesized by a new efficient method. Here we demonstrated that 5-benzyltriazinediones substituted in position para of the benzyl group with halogens provide compounds endowed with interesting selectivity for the Prokineticin receptor 1 (PKR1). BRET technology indicates that such substitution results in increas...
4417
1948
OPTIMIZATION OF CAROTENOIDS PRODUCTION BY RHODOTORULA MUCILAGINOSA
Optimization of total carotenoids production is dependent on various cultural and physical parameters for pigmented yeasts. The carotenoid production of the red yeast Rhodotorula mucilaginosa MTCC11835 was optimized using response surface methodology. The carotenogenesis in yeasts is known to be affected by different nutritional factors and environmental stress factors. Effect of various growth pa...
4885
2473
EVALUATION OF ANTICANDIDAL ACTIVITIES OF SPIRULINA METABOLITE AGAINST CANDIDA ALBICANCE
In this pilot study, Zarrouk medium was optimized in terms of biomass production and metabolites for the culture growth of, Spirulina species; Spirulina maxima and Spirulina platensis and their extract were tested against a nosocomial fungal species Candida albicans (C. albicans) to explore anticandidal activity. The corresponding growth and metabolite were measured in terms of turbidity, chloroph...
6582
2335