Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
PREPARATION AND EVALUATION OF SIMVASTATIN ORODISPERSIBLE TABLETS CONTAINING SOY POLYSACCHARIDE AND POTASSIUM POLACRILLIN AS NOVEL SUPERDISINTEGRANTS
Oral bioavailability of Simvastatin is very low (5%) due to bad solubility and effect of first pass. The aim of this work is to enhance its solubility and reformulating it as orodispersible tablet to overcome the two problems. Simvastatin solid dispersions in β- cyclodextrin, hydroxylpropyl-β-cyclodextrin, and hydroxylbutyl-β-cyclodextrin were prepared in different drug: polymer ratios namely 1...
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ANTIOXIDANT AND ANTICANCER THERAPEUTIC POTENTIALITY OF MUSHROOMS: A REVIEW
Cancer is a substantial world health threat, & a largest cause of death in peoples of various age groups and economic backgrounds. This dramatic increase in the global burden of cancer has spurred research and many pharmacological studies as an attempt to limit the progression of this disease. Painful, expensive chemotherapy by dietary supplements have come forth as a novel significant approac...
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ULTRADEFORMABLE SYSTEM: A CARRIER FOR TRANSDERMAL DRUG DELIVERY
The delivery of therapeutic agents transdermally has received considerable interest because of the safety and convenience of drug administration via this route. Recently, various strategies have been used to augment the transdermal delivery of bioactives. A transfersome is an artificial vesicle designed to be like a cell vesicle, and used to deliver drugs or genetic material into a cell. Transfe...
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CHEMICAL COMPOSITION OF ESSENTIAL OIL FROM LEAVES AND FLOWERS OF INULA VISCOSA (L.) IN AL-QADMOUS REGION, SYRIA
Leaves and flowers of Inula viscosa (L.) were collected from fields in Al-Qadmous, Syria. Essential oil was isolated by classical method of hydro distillation using the Clevenger-type apparatus. Its chemical composition was analyzed by GC/MS. The analysis led to the identification of48 and 43 components in flowers and leaves, respectively. Essential oils were characterized by a high content of oxy...
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QUORUM QUENCHING ABILITY OF DIETARY SPICE CINNAMOMUM VERUM ON PATHOGENIC BACTERIA
Quorum sensing is a bacterial cell communication mechanism mediated through signal molecules such as AHL’s. Many opportunistic pathogens use these quorum sensing circuits to coordinate their virulence gene expression. Wide range of naturally occurring substances particularly plant extracts have been evaluated for their ability to modulate quorum sensing in Gram-negative bacteria. Prelimi...
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COMPARATIVE EFFECT OF DIFFERENT HIGH FUNCTIONALITY EXCIPIENTS ON VARIOUS CHARACTERISTICS OF VARDENAFIL HCL TABLETS (BCS II DRUG)
Direct Compression is becoming a preferred manufacturing process in order to speed up the manufacturing and reduce costs. Although a major requirement for direct compression process is selection of excipients with the optimum physical characteristics that increase final flowability and compressibility of the ready for compression (RFC) tableting blend. By using combinations of excipients and novel...
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2091
DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF RITONAVIR IN TABLET DOSAGE FORM
A simple, precise, accurate and repeatable method for bulk and tablet dosage form of Ritonavir have been developed using spectrophotometric method. Differential spectrophotometric method was used. The developed method was validated according to ICH (Q2R1) guidelines and was found to be accurate, precise and specific. Amplitude difference was taken at absorbance maxima at 246 nm and absorbance mini...
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DIRECT SHOOT REGENERATION FROM INTER NODAL EXPLANTS OF MENTHA VIRIDIS L.
Adventitious bud regeneration from internode explants of Mentha viridis L. was achieved shoots from nodal segments grown in vitro, were cut in to pieces and uses as sources of explants. Organogenesis was induced from internodal explants cultured on Murashige and Skoog (MS) medium containing different combinations of 6, Benzylaminopurine (BAP) and Kn under 16 hr photoperiod and at a temperature o...
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PHYTOCHEMICAL SCREENING AND ANTIMICROBIAL ACTIVITY ON THE FRUITS OF HUGONIA MYSTAX L. (LINACEAE)
An ethnomedicinal plant, Hugonia mystax L., was examined for preliminary phytochemical screening and antimicrobial activity. Preliminary phytochemical screening showed the presence of various classes of secondary metabolites such as flavonoids, phenols, saponins, steroids, tannins and terpenoids. Antimicrobial activity of petroleum ether, chloroform, ethanolic and aqueous fruits extracts showed ...
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MEDICINAL PLANTS WITH POTENT ANTIOXIDANT CONSTITUENTS
Oxygen free radicals induce damage due to peroxidation to bio-membranes and also to DNA, which leads to tissue damage, thus cause occurrence of a number of diseases and biochemical disorders. Antioxidants neutralize the effect of free radicals through different ways and may prevent the body from various diseases. Antioxidants may play vital role in the metabolic disorders. India stands with highes...
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