Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
IN VITRO CYTOTOXICITY OF MADHUCA INDICA AGAINST DIFFERENT HUMAN CANCER CELL LINES
Cancer is a public health problem all over the world. Large number of plants and their isolated constituents has been shown to potential anticancer activity. Ethanolic whole plant extract of Madhuca indica showed in vitro cytotoxicity against different human cancer cell lines such as lung, neuroblastima, and colon. There was no growth of inhibition recorded against liver cancer cell line. Sulforho...
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FORMULATION AND IN-VITRO EVALUATION OF SUSTAINED RELEASED GLIBENCLAMIDE MICROSPHERES
In the present investigation, an attempt has been made to prepare sustained release microspheres of Glibenclamide by using Eudragit RS 100 as rate retardant polymer. Microspheres were successfully prepared by non-aqueous emulsion solvent evaporation method. Magnesium stearate was used as hydrophobic dispersant and droplets stabilizer. The yields were varies from 90-97% and encapsulation efficacy i...
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ISOLATION AND CHARACTERIZATION OF POLYPHENOLIC COMPOUND QUERCITIN FROM PHYLLANTHUS EMBLICA
The curative parts of medicinal plants are not simply its woody stem or its leaves but the number of chemical compounds (phytoconstituents) it produces and uses for its own growth like flavonoids, alkaloids, gum, mucilage, protein, carbohydrate etc. The genus Phyllanthus is widely used in medicine but still lot of work left to explore this genus. So the species, Phyllanthus emblica which is widely...
3309
1270
FORMULATION AND CHARACTERIZATION OF BAMBUTEROL HYDROCHLORIDE FAST DISSOLVING TABLET USING VARIOUS SUPERDISINTEGRANTS
Bambuterol HCl is a potent anti-asthmatic agent, act by stimulation through beta-adrenergic receptors of intracellular adenylcyclase. Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells. In the present study, an attempt has been made to prepare fast dissol...
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CYTOTOXIC EFFECT OF CRUDE EXTRACTS OF ACACIA NILOTICA
The cytotoxic effect of crude extracts (n-hehane, ethyl acetate and chloroform soluble fractions) of root of Acacia nilotica was observed by brine shrimp lethality bioassay. The LC50 values of n-hexane, ethyl acetate and chloroform soluble fraction found to be 1.956, 2.079 and 1.981 respectively indicating that the some of the compounds of the extract are biologically active. From this experiment,...
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FORMULATION AND EVALUATION OF ALLYLESTRENOL IMMEDIATE RELEASE TABLETS
Among the different routes of administration, the oral route of administration continues to be the most preferred route due to various advantages including ease of ingestion, avoidance of pain, versatility and most importantly patient compliance. The different dosage forms include tablets and capsules. Recently immediate release tablets have started gaining popularity and acceptance as a drug deli...
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IN-VITRO ANTI-OBESITY ASSAY OF ALCOHOLIC AND AQUEOUS EXTRACTS OF CAMELLIA SINENSIS LEAVES
Obesity is one of the main public health problems in developed countries. It is considered to be a risk factor associated with the genesis or development of major chronic diseases, including cardiovascular disease, diabetes, and cancer. Many botanicals may provide safe, natural, and cost-effective alternatives to synthetic drugs. The results of this study show promise for the potential use of thes...
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FTIR AND RAMAN SPECTROSCOPY AS A TOOL FOR ANALYZING SUSTAINED RELEASE HYDROGEL OF CIPROFLOXACIN/CARBOPOL POLYMER
Purpose: Ciprofloxacin, an antibacterial agent, is having low solubility in aqueous solution and high rate of absorption from the stomach. It is precipitated at alkaline pH which leads to erratic absorption of the drug from small intestine. To overcome these difficulties, many researchers have prepared different formulations of Ciprofloxacin. But till now very few formulations are available from w...
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IRON OVERLOAD AND GROWTH OF THALASSEMIC PATIENTS IN MARWAR REGION
Growth disturbances are a major clinical feature of thalassemic patients. Regular blood transfusions and iron-chelation therapy greatly contribute to the quality and longevity of thalassemic patients. The main objective of present study was to compare the current growth of Thalassemia major patients, taking into accounts the iron overload, transfusion and iron chelation therapy, therefore we plann...
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IN-VITRO ANTIOXIDANT AND PHYTOCHEMICAL SCREENING OF ETHANOLIC EXTRACT OF ALPINIA PURPURATA
Plants containing bioactive substances have increasingly become the object of research studies, opening alternative paths for therapeutic treatments or revealing substances that could later be explored and synthesized to produce pharmaceutical, cosmetic and agrochemical formulations. Alpinia purpurata have strong effect on H2O2 induced oxidative damages. The extract of Alpinia purpurata showed a h...
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