Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
PHYTOCHEMICAL SCREENING, CYTOTOXIC AND CNS DEPRESSANT ACTIVITIES OF HOLARRHENA ANTIDYSENTERICA LEAVES AND SEEDS
Methanolic extract of leaves and seeds of Holarrhena antidysenterica was appraised individually to investigate the cytotoxic activity and CNS depressant activity of the leaf extract was observed adopting both open field test and hole cross test. Phytochemical screening with the leaf extract only, suggested the presence of alkaloids, cardiac glycoside, steroids, flavonoids, tannins and saponin. Bri...
4893
2236
DOCTOR’S PRESCRIBING TRENDS OF ANTIBIOTICS FOR OUT PATIENTS IN BANGLADESH: A CROSS-SECTIONAL HEALTH SURVEY CONDUCTED IN THREE DISTRICTS
Objectives: The aim of this study was to analyze and evaluate the practitioners’ prescribing habits of antibiotics in three cities of Bangladesh. Methods: A cross sectional health survey with manual data collection was carried out with a standardized questionnaire over three month period at the three cities Rajshahi, Jessore and Comilla in Bangladesh. The collected data was subjected to simple d...
5168
2379
IN- VITRO ANTIMICROBIAL ACTIVITY OF EXTRACTS OF SEEDS OF CLEOME VISCOSA LINN.
Since ancient times, plants have got medicinal importance. Ethno medicinal use of plants is very common in rural parts of India. Various constituents of these plants have shown profound therapeutic and prophylactic activities. The present research work is conducted to investigate invitro antimicrobial activity of various extracts of seeds of plant Cleome viscosa Linn. The petroleum ether, chlorofo...
4601
1839
NOVEL AND VALIDATED SPECTROPHOTOMETRIC DETERMINATION OF BUDESONIDE FROM BULK AND TABLETS USING MIXED HYDROTROPIC SOLUBILIZATION TECHNIQUE
A novel, safe, accurate, sensitive and economic Spectrophotometric method was developed by application of mixed hydrotropy using solution containing 45% urea and 5% sodium citrate as hydrotropic solubilizing agent for the quantitative determination of poorly water-soluble budesonide from bulk and tablet dosage form. The solubility of budesonide increases more than 20 times in mixed hydrotropic s...
4551
2289
COMPARATIVE ANTIBACTERIAL STUDY OF DIFFERENT EXTRACT OF POMEGRANATE AND ITS WILD VARIETY
Plants have traditionally provided a source of hope for novel drug compounds, as plant herbal mixtures have made large contributions to human health and well-being. We report in this work for the first time, the potent antibacterial activity of Punica granatum and its wild form daru. Ethanol, petroleum ether and distilled water extract of fruit’s white membrane were screened for in vitro activit...
4965
1508
PHARMACOGNOSTICAL INVESTIGATIONS ON IPOMOEA AQUATICA FORSK.
Plants are a great source of medicines, which are useful in the treatment of various diseases. Ipomoea aquatica Forsk of family Convolvulaceae commonly known as Kalmisag or Nalanibhaji is being used as a green leafy vegetable and have great medicinal value in Indian medicine. It is used in Unani System of Medicine as carminative, lessens inflammation, useful in fever, jaundice, biliousness, bronch...
5388
2229
IMMUNOSTIMULATORY POTENTIAL OF N-BUTANOLIC FRACTION OF HYDROALCOHOLIC EXTRACT OF COSTUS SPECIOSUS KOEN. RHIZOME
The immunomodulatory potential of n-butanolic fraction of rhizome extract (hydroalcoholic) of Costus speciosus was evaluated. For this different models like estimation of serum Immunoglobulin level, carbon clearance test, delayed type hypersensitivity reaction and humoral antibody were used. In delayed type hypersensitivity reaction and humoral antibody titer , mice were immunized by injecting 20%...
5138
2007
BIOLOGICAL INVESTIGATIONS OF THE LEAF EXTRACT OF SPONDIAS PINNATA
The present study was done to evaluate in-vitro membrane stabilizing activity with human RBC, in-vivo neuropharmacological activity including open field and swimming test, gastrointestinal motility and acute toxicity of different leaf extracts of Spondias pinnata in Swiss albino mice following oral administration. In-vivo GI motility test was done by charcoal induced anti motility test, acute toxi...
6510
1732
E7010: INVESTIGATIONAL ANTICANCER AGENTS TARGETING THE MICROTUBULES
E7010 (N-[2-[(4-hydroxyphenyl)amino] – 3 pyridinyl] – 4 -methoxybenzenesulfonamide), an orally active sulfonamide antitumor agent that is currently in a Phase I clinical trial, showed rather consistent growth-inhibitory activities against a panel of 26 human tumor cell lines (IC50 = 0.06–0.8 µg/ml), in contrast to vincristine (VCR; IC50 = 0.0002–0.04 µg/ml), 5-fluorouracil (IC50 = 0.2...
5115
2091
PREPARATION AND EVALUATION OF MUCOADHESIVE GELLAN GUM IN-SITU GELS FOR THE OCULAR DELIVERY OF CARBONIC ANHYDRASE INHIBITOR NANOVESICLES
A novel approach was tested utilizing mucoadhesive in-situ gelling (ISG) Gellan Gum /HPMC solutions containing dispersions of methazolamide (MZA) loaded Spanlastic Vesicular systems (SVs). The tested systems were designed to combine high corneal permeability of SVs as well as ease of application and prolonged eye retention of ISGs. SVs consisted of Span 60 mixed with different ratios of edge activ...
5482
2564