Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
ISOLATION AND CHARACTERIZATION OF THE CHEMICAL CONSTITUENTS OF STELLARIA MEDIA LINN.
The studies on the constituents of aerial parts of Stellaria media Linn. (Caryophyllaceae) have led to the isolation and characterization of three new compounds ─ (1), (2), and (3). Structure elucidation of the new compounds was carried out using 1H NMR, 13C NMR, Mass spectrometry, together with other complementary techniques (UV and IR). The major findings of the study include: Compound 1 was s...
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ASSESSMENT OF KNOWLEDGE AND PRACTICE TOWARDS BIRTH PREPAREDNESS AND COMPLICATION READINESS AMONG WOMEN IN MEKELLE, NORTHERN ETHIOPIA: DESCRPTIVE CROSSECTIONAL
Background: Birth preparedness and complication readiness (BP/CR) are interventions designed to address the delays by encouraging pregnant women, their families, and communities to effectively plan for births and prepare for emergencies. Objective: To assess the knowledge and practice towards birth preparedness and complication readiness among women in Mekelle town, 2013. Methods and Materials: A ...
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QUALITY BY DESIGN IN THE DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD BY ULTRAVIOLET-VISIBLE SPECTROPHOTOMETRY FOR QUANTIFICATION OF HYDROXYCHLOROQUINE SULFATE
Developed originally as an antimalarial agent, the hydroxychloroquine sulfate (HCQ) is often used as a slow-acting anti-rheumatic drug in treating disorders of connective tissue. The methods of quantification of HCQ sulfate, despite the undeniable advantages, have certain limitations, such as high cost of operation and maintenance of equipment, sample processing and analysis of the results relativ...
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IN-VITRO AND IN-VIVO EVALUATION OF NIOSOMES CONTAINING CELECOXIB
Niosomes as a vesicular system are well documented for delivering drugs, in a controlled manner to enhance bioavailability and get better therapeutic effect over a longer period of time. Celecoxib is an NSAID, selective COX-2 inhibitor, which is used for treatment of rheumatoid arthritis, osteoarthritis, and acute pain. The present study dealt with the preparation and characterization of celecoxib...
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AFFECT OF GRANULE SIZES, TYPES AND CONCENTRATIONS OF LUBRICANTS AND COMPRESSION FORCES ON TABLET PROPERTIES
By using five different sieve sizes of ascorbic acid granules, affects of granule sizes on tablet properties, i.e. tablet weight and hardness have been studied with standard methods. Affects of lubricant types and concentrations on tablet properties, i.e. tablet hardness and disintegration time have also been studied by using magnesium stearate and sodium stearyl fumarate as the lubricants for pro...
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A FACTORIAL STUDY ON FORMULATION DEVELOPMENT OF IBUPROFEN TABLETS EMPLOYING STARCH 1500 AND PVP K 30
Ibuprofen, a widely prescribed anti-inflammatory and analgesic drug belongs to class II under BCS and exhibit low and variable oral bioavailability due to its poor aqueous solubility. Solid dispersion of ibuprofen in Starch 1500, a modified starch and polyvinyl pyrrolidone (PVP K 30) was investigated to enhance the dissolution rate and to develop ibuprofen tablets with fast dissolution characteris...
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CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF HARAMAYA PROPOLIS (BEE GLUE), ETHIOPIA
The present study was aimed at investigating the chemical composition and antifungal activity of Ethanol Extracted Haramaya propolis (EEHP). The GC-MS analysis of EEHP showed the presence of sixteen compounds and twelve compounds were identified by means of their retention times, by comparison of their mass spectra with the NIST 2005 library data and literature. The major constituents of EEHP were...
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FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF TELMISARTAN
The patients with sudden increase blood pressure have markedly reduced function ability and extremely restless, in such cases rapid onset of action is of prime importance. So the patients would be benefited from acute treatment by using Fast dissolving drug delivery system. Telmisartan is an Anti-hypertensive drug which is insoluble in water; hence the drug may be slowly or incompletely dissolves ...
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CAMELLIA SINENSIS LEAVES A NEW TREATMENT AGAINST URINARY TRACT INFECTION CAUSED BY PSEUDOMONAS FLUORESCENS AND SERRATIA SP
Urinary tract infection is the most common disease in females and males which is big threat of kidney failure. The increasing interest is in the powerful biological activity of medicinal plant containing bioactive compounds which paves way for the importance to determine their antibacterial activity. The bioactive chemical determination revealed the presence of bioactive constituents’ steroids, ...
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CYTOTOXIC EFFECT OF INK EXTRACTS OF CUTTLEFISH AND SQUID ON CHICK EMBRYO FIBROBLASTS
: The aim of the present study is to evaluate the cytotoxic effect of the ink extracts of different specis of cuttlefish (Sepia pharaonis female, Sepia pharaonis male, Sepiella inermis female, Sepia aculeata female) and squid (Loligo duvauceli female). The ink extracts were prepared by delipidation with acetone and extracted by Tris HCl buffer. The cytotoxic effect of the drug was studied using ...
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