Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
FORMULATION AND EVALUATION OF MICROCAPSULES OF TRIHEXYPHENIDYLE HYDROCHLORIDE BY SOLVENT EVAPORATION METHOD.
Trihexyphenidyle is a lipophilic antiparkinsonian drug with short half life. Practically slightly soluble in water makes formulation and delivery difficult. By formulating the same in the microcapsule by using biodegradable polymer Eudrajit L 100 and S 100, the half life and solubility can be altered and hence drug release pattern. Trihexyphenidyle microcapsules were prepared by solvent evaporatio...
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CRUDE ROOT EXTRACT OF ASPARAGUS RACEMOSUS AMELIORATES ACETAMINOPHEN INDUCED UREMIC RATS.
Now days, herbal medicines are widely used to treat, manage and cure the kidney diseases as well as reduce uremia, acute nephritis & nephritic syndrome. The present study was to evaluate the antiuremic and antioxidative effect of Asparagus racemosus (AR) on acetaminophen induced uremic male rats. The study was designed with 36 male albino rats which were randomly divided into 6 groups. Group I...
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FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF ACETAMINOPHEN
The present research work has been carried out for an optimized formulation of co-processed directly compressible vehicles in the preparation of the Acetaminophen mouth fast dissolving tablets (MFDTs). Acetaminophen was chosen due to its poor compression properties. Di-calcium Phosphate(DCP) was incorporated in the neutralized aqueous starch dispersion to prepare co-processed excipient. Co-process...
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SYNTHESIS AND BIOLOGICAL SCREENING OF BENZIMIDAZOLE DERIVATIVES
The synthesis of benzimidazoles derivative involves subsequent synthesis of 4-(2-chloro-ethoxy)-benzaldehyde, 4 methyl benzaldehyde followed by benzimidazoles derivative by reaction between amines derivatives and o-phenylenediamine in dimethyl farmamide (DMF) as solvent in the presence of iodine as a catalyst. Iodine is a commercial and environmentally benign catalyst. The yield of all benzimidazo...
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SALICYLIC ACID AND CHITOSAN MEDIATED ABIOTIC STRESS IN CELL SUSPENSION CULTURE OF ANDROGRAPHIS PANICULATA (BURM.F.) NEES. FOR ANDRO-GRAPHOLIDE SYNTHESIS
Quantitative and qualitative improvement of rare and valuable bioactive plant products is promisingly possible using In-vitro cell culture techniques. The present investigation was conducted with the aim to elicit the synthesis ofandrographolide by subjecting cultured cells of Andrographis paniculata to Salicylic acid (SA) and Chitosan mediated abiotic stressCell suspension culture of Andrographis...
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MOLECULAR CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF OCTOPUS AEGINA AND OCTOPUS DOLFUSII IN GULF OF MANNAR COAST
Antibacterial activity and protein content was studied in two species of octopus belonging to the family Octopoda. The highest zone of inhibition of about 34mm and 28mm were obtained against Vibrio parahaemolyticus and theprotein content was 107.16µg/L and 136.20µg/Lin Octopus dolfusii and Octopus aegina, respectively. SDS profile revealed bands of molecular weight of about 32.83 KDa to 72.36 KD...
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SPECTROFLUORIMETRIC DETERMINATION OF TOLTERODINE TARTARATE IN PURE FORM AND PHARMACEUTICAL PREPARATION
A Simple, rapid, sensitive, accurate and precise spectrofluorimetric method was developed for the determination of tolterodine tartrate (TOL) in bulk powder and in pharmaceutical preparation. This method is based on measuring the native fluorescence of TOL in methanol at 313 nm after excitation at 285 nm using 1 ml of phosphate buffer pH 6. All variables that affect fluorescence intensity such as ...
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ANTIOXIDANT ACTIVITY OF PLANTS AT CHINNATIRUPATHI, SALEM, TAMIL NADU, INDIA
This study was carried out during March - April 2013. The fresh leaves collected were extracted with water and used for antioxidant assay. Nitric oxide scavenging activity, Reducing power assay, Metal chelating activity, Phosphomolybdenum activity was assayed and also secondary metabolites such as phenol, flavonoid was estimated. These metabolites play a major role in antioxidant activity. Here,...
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ACETYLATION AND CHARACTERIZATION OF ENSET STARCH AND EVALUATION OF ITS DIRECT COMPRESSION AND DRUG RELEASE SUSTAINING PROPERTIES
Enset (Ensete ventricosum, Musaceae), a plant widely cultivated in south and southwest of Ethiopia, has been shown to be a rich source of starch. In an effort to produce directly compressible matrix-forming excipient, native enset starch was acetylated. Starch acetates (SA) with degrees of substitution (DS) of 0.672 and 2.142 were evaluated. Fourier transform infrared (FTIR) spectra of the modifie...
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PHARMACOGNOSTICAL AND PHYTOCHEMICAL INVESTIGATION OF EUPHORBIA PROSTRATA AIT.
Euphorbia prostrata Ait.(Euphorbiaceae) is a small, prostrate, annual green herb sometime purple tint in colour. It is widely distributed globally and used as antihemorrhoidal, anti-inflammatory, analgesic, hypolipidemic, antidiabetic, antidirroheal, antiasthmatic and for various skin diseases. The microscopy of root shows the presence of obliterated cork cells, phelloderm, cortex, endodermis, phl...
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