Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 5.2 | 2.73 | 0.64 |
SIMULTANEOUS SPECTROPHOTOMETRIC ESTIMATION OF CIPROFLOXACIN AND ORNIDAZOLE IN TABLET DOSAGE FORM
Three simple sensitive, rapid, accurate and economical methods were developed for simultaneous estimation of Ciprofloxacin & Ornidazole in bulk and its pharmaceutical formulations. First method was based on the simultaneous equation, second method was based on Q-Analysis (Absorbance ratio method) and third method was based on multicomponent mode. The absorption maxima for Ciprofloxacin and Orn...
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1700
FORMULATION AND IN-VITRO EVALUATION OF MUCOADHESIVE BILAYERED BUCCAL TABLETS OF ROSUVASTATIN CALCIUM
The purpose of this research work was to establish mucoadhesive buccal device of Rosuvastatin Calcium(RC) in the form of bilayered tablet. The tablets were prepared using natural gums like Xanthan gum, Tamarid gum, Gellan gum and Chitosan as bioadhesive polymers to impart mucoadhesion as well as permeation enhancement property to the formulation. Ethyl cellulose & magnesium stearate were added...
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2257
VIROSOMES: A NOVEL VACCINATION TECHNOLOGY
Vaccine development has continuously shifted away from live attenuated or inactivated whole organisms. Although this approach having good efficacy but for improvement on comparison of risk/benefit ratio which needs improvement due to their highly complex compositions which result in safety concerns. As a consequence, a number of indications remained unadressed. The next generation vaccines represe...
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1766
U.V SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF MESALAZINE IN BULK AND ITS PHARMACEUTICAL DOSAGE FORMS
Mesalazine is used, either orally or rectally, as an anti-inflammatory agent in treating ulcerative colitis and, to a lesser extent, Crohn's disease. Mesalazine is a white to pinkish crystalline powder. It is slightly soluble in cold water and alcohol; more soluble in hot water, soluble in hydrochloric acid. A simple UV spectrophotometric method was developed for the determination of Mesalazine (M...
7457
1980
RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF RANITIDINE HYDROCHLORIDE AND DOMPERIDONE IN COMBINED TABLET DOSAGE FORM
A simple reverse phase HPLC method was developed for the simultaneous estimation of Ranitidine hydrochloride and Domperidone present in combined tablet dosage forms. Efficient chromatographic separation was achieved on Phenomenax C18 stationary phase (250 X 4.6 mm i. d., 5μ particle size) with simple mobile phase combination of phosphate buffer: acetonitrile: methanol 40: 30: 30 (V/V/V) in an iso...
5564
1699
SYNTHESIS, ANTI-VIRAL AND CYTOTOXICITY STUDIES OF SOME NOVEL N-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES
A series of novel N-substituted benzimidazole derivatives were synthesized and screened anti-viral activity against a HIV -1 and -2 in MT-4 cells. New compounds were synthesized through modifying the N-1 hydrogen of benzimidazole moiety with the substitution of sulphanilamide, sulphadimidine, sulphamethoxazole, 2-aminopyridine, pthalamide, benzamide, nicotinamide, anthranilic acid and 2- marcapto-...
3429
1607
STUDY OF PHYTO CHEMICAL, ANALGESIC AND ANTI ULCER ACTIVITY OF EXTRACTS OF AERIAL PARTS OF CARDIOSPERMUM HALICACABUM LINN.
The dried aerial parts of Cardiospermum halicacabum Linn were subjected to extraction using the solvents (petroleum ether, chloroform, Ethyl acetate and ethanol) in increasing order of polarity. The prepared extracts were then subjected to preliminary phytochemical analysis. It was found plant possesses carbohydrates, alkaloids, sterols, flavanoids and saponins. All extracts were selected for furt...
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1518
ROUTINE BLEEDING TECHNIQUES IN LABORATORY RODENTS
Collecting blood from Lab animals is necessary for a wide variety of scientific studies, and there are a number of efficient methods available. It is important to remember that blood collection can stress the animals, and may have an impact on the outcome of research data. Potential adverse affects viz. Hypovolemic shock, anemia, stress, haemorrhage, bruising, thrombosis; infection at the site of...
10459
2224
IN VIVO AND IN VITRO ANTIOXIDANT ACTIVITIES OF COUMARIN ON CHEMICAL INDUCED HYPERGLYCEMIC RATS
The present study was aimed at investigating the antioxidant activities of coumarin in streptozotocin (STZ)-nicotinamide (NA) induced type 2 diabetic rats. Diabetes was induced in experimental rats by a single intraperitoneal (i.p.) injection of STZ (45 mg/kg body weight (b.w.)), 15 min after the i.p. administration of NA (110 mg/kg b.w.). Diabetic rats were administered coumarin intragastrically ...
3353
1364
EVALUATION OF STRESS IN EXPERIMENTAL PHARMACOLOGY
Stress undoubtedly has become an integral part of human life. Stressful conditions have a derogative effect on normal physiological functions leading to a variety of disease states. Many of the most prevalent diseases of the modern era like hypertension, diabetes, behavioral disorders, etc. have been implicated as one of the many ill-effects of chronic stress. Experimental models are required to b...
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