Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
SYNTHESIS, ANTI-VIRAL AND CYTOTOXICITY STUDIES OF SOME NOVEL N-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES
A series of novel N-substituted benzimidazole derivatives were synthesized and screened anti-viral activity against a HIV -1 and -2 in MT-4 cells. New compounds were synthesized through modifying the N-1 hydrogen of benzimidazole moiety with the substitution of sulphanilamide, sulphadimidine, sulphamethoxazole, 2-aminopyridine, pthalamide, benzamide, nicotinamide, anthranilic acid and 2- marcapto-...
2752
1409
FORMULATION AND DEVELOPMENT OF LIPOSOMAL GEL FOR TOPICAL DRUG DELIVERY SYSTEM
Aim: The aims of this study were to develop liposome enriched Dexibuprofen liposomal hydrogels for topical delivery, perform in vitro release studies and in vivo permeation studies through mice/rat skin, and evaluate the efficacy of liposomal gels against inflammation induced rats. The purpose was to provide the delivery of the topical drug at a sustained rate across intact skin to improve bioavai...
8253
3678
COMPARATIVE STUDIES ON SKIN PERMEATION OF MICONAZOLE USING DIFFERENT NOVEL CARRIERS
Purpose: Miconazole nitrate is a widely used antifungal agent but its use in topical formulation is not efficacious because deep ereated fungal infections are difficult to treat with conventional topical formulation. The purpose of this study was to prepare miconazole incorporated different novel carriers such as liposomes, ethosomes and to compare their in vitro skin permeation studies with plane...
3424
1416
SIMULTANEOUS ESTIMATION OF AMITRIPTYLINE HYDROCHLORIDE AND PERPHENAZINE BY ABSORPTION RATIO (Q- ANALYSIS) UV SPECTROPHOTOMETRIC METHOD IN COMBINED TABLET DOSAGE FORM
The simple, accurate and precise absorption ratio method has been developed for the simultaneous estimation of amitriptyline HCl and perphenazine in combined tablet dosage form. The λmax of amitriptyline HCl and perphenazine were found to be 240.0 nm and 258.0 nm respectively. For the estimation by Q-analysis method, the λmax those selected were 240.0 nm and an isoabsorptive point for both the d...
4431
1646
DEVELOPMENT AND EVALUATION OF MELT- IN- MOUTH TABLETS BY SUBLIMATION TECHNIQUE
In the present study Rizatriptan benzoate, which is the bitter drug requires taste, masking. β- Cyclodextrin is used in taste masking, which improves the patient compliance and also increases the rate of dissolution. Solid dispersion of drug and β- Cyclodextrin were prepared which was optimised in 1: 8 ratios, which gave satisfactory results for taste masking. This was then characterised using D...
2888
1079
ANTI ULCER ACTIVITY OF HELIOTRPIUM INDICUM LEAVES EXTRACT
The objective of present study is to evaluate the anti ulcer activity of ethanol extract of leaves of Heliotropium indicum. The ethanol extract of H. indicum was investigated for its anti ulcer activity against Aspirin plus pylorus ligation induced gastric ulcer in rats, HCl- Ethanol induced ulcer in mice and water immersion stress induced ulcer in rats. The antiulcer activity was assessed by dete...
1693
1152
PHARMACOGNOSTIC STANDARDIZATION OF MADHUCA INDICA LEAF AND STEM, AN IMPORTANT MEDICINAL PLANT
Objective: To evaluate the pharmacognostic characters of Madhuca indica J.F. Gmel leaf and stem an important traditional medicinal plant. Method: In the present investigation, pharmacognostic parameters like macroscopic and microscopic and powder characters of leaf and stem were studied. Preliminary phytochemical and physiochemical analyses were done by using reported methods. Fluorescent behavior...
4027
1493
ANTIBACTERIAL ACTIVITY OF THE LEAVES, BARK, SEED AND FLESH OF MORINGA OLEIFERA
Moringa oleifera belongs to an onogeneric family of shrubs and tree, Moringaceae. In the Dravidian language there are many local names for Moringa oleifera but all are derived from the generic root “Morunga”. It has anticancer, anti-inflammatory activity and thyroid status regulator efficacies. An experiment was carried out to study the antibacterial activity of different solvent e...
6622
1572
ANTI ULCER ACTIVITY OF HELIOTRPIUM INDICUM LEAVES EXTRACT
The objective of present study is to evaluate the anti ulcer activity of ethanol extract of leaves of Heliotropium indicum. The ethanol extract of H. indicum was investigated for its anti ulcer activity against Aspirin plus pylorus ligation induced gastric ulcer in rats, HCl –Ethanol induced ulcer in mice and water immersion stress induced ulcer in rats. The antiulcer activity was assessed by de...
2610
1075
HISTOCHEMICAL AND PHYTOCHEMICAL MARKERS FOR THE AUTHENTICATION OF AYURVEDIC RAW DRUG HALLAKAM (KAEMPFERIA ROTUNDA) AND ITS MARKETED ADULTERANT
Comparative pharmacognostic and phytochemical studies are the reliable source to identify the genuine raw drug from its adulterants. This paper deals with the characterization of the repute ayurvedic drug hallakam from its substitute/adulterants. Ayurvedic experts equated rhizomes of Kaempferia rotunda L. of Zingiberaceae as hallakam and in certain market samples Lagenandra toxicaria Dalz. is also...
4240
1544