Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY OF LEUCAS ASPERA
The purpose of the current work was to conduct phytochemical screening and antioxidant activity of different extracts of Leucas aspera. The dried powder of the whole plant was extracted with n-hexane, ethyl acetate and ethanol which were subjected to various chemical tests to ascertain the main constituents of the plant. The results revealed the presence of significant amounts of alkaloids, glycos...
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1613
SYNERGISTIC ANTIMICROBIAL EFFECT OF COW URINE AND AZADIRACHTA INDICA ON INFECTIOUS MICROBES
The study is aimed towards studying synergistic antimicrobial effect of cow urine and Azadirachta indica against bacterial, fungal and yeast strains. Mother Nature is the best healer. Last few decades have seen tremendous development in pharma sector. Even though these industries have produced a large number of new drugs and new antibiotics and so does the resistance among microbes is growing. B...
3615
1346
SYNTHESIS AND ANTICANCER ACTIVITY OF SOME NOVEL PYRIMIDINE DERIVATIVES
A number of 2-amino-4-(2', 5'-dimethyl-3'-furyl)-6-(aryl)-pyrimidines 4(a-n) have been synthesized by treating the 1-(2', 5'-dimethyl-3'-furyl)-3-(aryl)-2-propen-1-one (3a-n) with guanidine hydrochloride in presence of potassium hydroxide and ethanol. All these compounds were characterized by means of their IR, 1H NMR spectroscopic data and microanalyses. When these compounds were evaluated for an...
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2138
ANTI-INFLAMMATORY ACTIVITY OF CROCUS SATIVUS EXTRACT IN EXPERIMENTAL ARTHRITIS
Rheumatoid arthritis is one of the most serious medical problems leading to bone and cartilage destruction. The disease affects approximately 1% of the total world population. Mostly the women are affected. The pathogenesis of the disease is still not clearly understood. Free radicals and inflammatory molecules such as TNF-α, IL-1β etc have been recognized as major players in the progression of ...
4749
1322
FORMULATION DESIGN AND IN-VITRO EVALUATION OF ZOLMITRIPTAN GASTRORETENSIVE FLOATING MATRIX TABLETS FOR MANAGEMENT OF MIGRAINE
Objective: The objective of the present investigation was to formulate and evaluate hydrodynamically balanced floating matrix controlled drug delivery system of Zolmitriptan by increasing its residence time and improves the bioavailability. Methods: Twelve different formulations of floating tablets were prepared using direct compression technique with hydrophilic polymers such as HPMC K4M, K15M, K...
4527
1604
CHARACTERIZATION AND SCREENING OF BIOACTIVE COMPOUNDS IN THE EXTRACT PREPARED FROM AERIAL ROOTS OF FICUS BENGHALENSIS
Ficus benghalensis is has been used in traditional medicinal practices such as Ayurveda, Unani, Siddha and homoeopathy. All parts of the tree such as fruits, aerial roots, bark and leaves are known to be traditionally associated with diarrhea, dysentery, menorrhagia, nervous disorders and tonic properties. However, in Ayurveda it is mainly known for the diabetes treatment.There are no reports givi...
6345
2407
SELF MICROEMULSIFYING DRUG DELIVERY SYSTEM: A LIPID BASED DRUG DELIVERY SYSTEM
Administration of drug by oral route is the most effective and acceptable route as it has better therapeutic efficacy, low cost and good patient compliance. More than 40% of new drugs are poorly water soluble. These drugs present development challenges and also have poor bioavailability. Although many formulation approaches like solid dispersions, complexation, pH modification exist, novel lipid b...
10406
2455
3D-QSAR AND CONTOUR MAP ANALYSIS OF TARIQUIDAR ANALOGUES AS MULTIDRUG RESISTANCE PROTEIN-1 (MRP1) INHIBITORS
One of the major obstacles to the successful chemotherapy towards several cancers is multidrug resistance of human cancer cells to anti-cancer drugs. An important contributor to multidrug resistance is the human multidrug resistance protein-1 transporter (MRP1), which is an efflux pump of the ABC (ATP binding cassette) superfamily. Thus, highly efficacious, third generation MRP1 inhibitors, like t...
8430
1698
A COMPARISON STUDY OF LIPOSOMES, TRANSFERSOMES AND ETHOSOMES BEARING LAMIVUDINE
The aim of this study was to compare the skin permeation of liposomes, transfersomes and ethosomes of lamivudine under non-occlusive conditions. The liposome and transfersomes prepared by thin film hydration method and ethosomes were prepared by slight modification on hot method. The Liposomal formulation (LP1) ethosomal formulation (ET2) and transfersomal (TF2) formulation showed highest entrapme...
10968
2007
PHYTOCHEMICAL ANALYSIS OF METHANOLIC EXTRACT OF SEEDS OF MUCUNA PRURIENS BY GAS CHROMATOGRAPHY MASS SPECTROMETRY
Mucuna pruriens is a climbing legume used in the treatment of various ailments. It is commonly known as Cowitch or velvet bean. Traditionally, it was used in treating male infertility. The main aim of this study was to identify the bioactive materials present in the methanol extract of Mucuna pruriens seeds by Gas Chromatography Mass Spectrometry (GC-MS) technique. The analysis by GC-MS reveals th...
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1795