Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 5.2 | 2.73 | 0.64 |
EFFECT OF AQUEOUS EXTRACT OF CRYPTOLEPIS SANGUINOLENTA ADMINISTRATION ON THE METABOLISM OF CHLOROQUINE VIA CYTOCHROME P450 ISOZYMES
Concurrent administration of herbal medicines and conventional drugs is a common practice globally, especially as the patronage of medicinal plants increases across the world. This study aimed to determine the effect of Cryptolepis sanguinolenta administration on the metabolism of chloroquine by evaluating specific Cytochrome P450 isozymes. Reconstituted freeze dried Cryptolepis sanguinolenta was ...
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INVESTIGATING AND SEQUENCING OF THIOL-SPECIFIC ANTIOXIDANT GENE IN A SYRIAN STRAIN OF LEISHMANIA TROPICA
Cutaneous leishmania is a common medical problem in Syria, which has become yet more widespread in most of the Syrian governorates after the current war. An effective vaccine is needed to prevent a large scale spread of leishmaniasis in the country. In this regard, protein vaccination has shown promising prospects of creating this much-needed vaccine. Thiol Specific Antioxident (TSA) plays a funda...
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NEUROTHERAPEUTIC EFFECT OF BERGENIN ON CUPRIZONE-INDUCED DEMYELINATION BY REGULATING NEUROLOGICAL FUNCTIONS ASSOCIATED WITH MOTOR ACTIVITY, OXIDATIVE STRESS, AND HISTOLOGICAL ALTERATIONS IN THE CORPUS CALLOSUM OF C57BL/6 MICE
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system characterized by Neuroinflammation, oligodendrocyte loss, and axonal pathology. Bergenin, a chief phytochemical constituent of Bergenia species, has been shown to exert anti-inflammatory and antioxidant effects. The cuprizone (CPZ) model is an established mouse model of MS and causes demyelination and induces ...
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A TRAILBLAZING ENDEAVOUR TO EXPLORE THE ROLE OF TULASI PUSHPA AS SANDHANA DRAVYA (FERMENTING AGENT) IN SANDHANA KALPANA
Sandhāna kalpanā (Fermentation process) is a unique procedure implemented in Ayurveda for the preparation of fermented alcoholic and acidic medicinal formulations. Sandhāna dravyās (fermenting agents) act as fermentation initiators in them. The commonly used Sandhāna dravyās are Dhātakipuṣpā (flowers of Woodfordia fruticosa), madhūkapuṣpā (flowers of Madhuka indica) and yeast. Almost...
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EVALUATION OF THE NEUROPROTECTIVE ACTIVITY AND COGNITIVE ABILITY OF AEGLE MARMELOS ETHANOLIC LEAVES EXTRACT AND ESTROGEN IN ESTROGEN COMPROMISED FEMALE RATS USING SCOPOLAMINE-INDUCED ALZHEIMER’S MODEL
Alzheimer’s disease, the most common form of dementia, is higher in elderly women than men. Escape latency time of Group 3 (Donepezil) and Group 6 (AMEE and Estradiol) is less than group 2 (Scopolamine and letrozole). As shown by the results, the decrease in AChE level in Group 3 (Donepezil) and Group 6 (AMEE and Estradiol) indicates restoration of Ach level in the brain. Increased GSH level was...
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LIP REPOSITIONING AS AN ADJUNCT TO THE TREATMENT OF EXCESS GINGIVAL DISPLAY: CASE SERIES
A smile is a basic and universal facial expression and is an interaction between the teeth, the lip, and the gingival outlines. The smile plays a significant role in the communication and appearance of an individual. As the esthetic demand increases, obtaining a “perfect smile” has become a major goal for many people of this generation. One of the most important features of dental and facial a...
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ANTIDIABETIC POTENTIAL OF HYDROALCOHOLIC EXTRACT OF LEAVES OF NYCTANTHES ARBORTRISTIS IN ADRENALINE AND ALLOXAN-INDUCED DIABETIC RATS
Diabetes mellitus, a metabolic disorder, is a serious universal health problem. The incidence of the disease is increasing in the world in all ethnic groups. Various medicinal plants are conventionally used in the treatment or management of the disease. In this investigation, an attempt was taken to evaluate the antidiabetic property of hydroalcoholic extract of leaves of Nyctanthes arbortristis i...
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FORMULATION, OPTIMIZATION AND EVALUATION OF GLIMEPIRIDE TRANSFERO-SOMAL GEL FOR ANTIDIABETIC ACTIVITY IN RATS
Transferosomes are a special liposome type consisting of phosphatidylcholine and an edge activator. Glimepiride is a second-generation sulphonylurea exerting its effects in patients with type II Diabetes. Glimepiride is hydrophobic in nature possess less solubility and permeability. The study aims to formulate, optimize and evaluate Glimepiride Transferosomal gel for antidiabetic activity in Rats....
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EVALUATION OF THE ANTIHYPERTENSIVE ACTIVITY OF R-(+)-PULEGONE IN L-NAME INDUCED HYPERTENSIVE WISTAR RATS
Objectives: The present study was aimed to assess the anti-hypertensive effect of PLG in L-NAME-induced hypertensive rats. Methods: Wistar rats of 200-240g were given L-NAME (40 mg/kg body weight/day/p.o.) in drinking water daily for 4 weeks to induce hypertension. Rats were randomly divided into six groups: control, L-NAME control, Verapamil (20 mg/kg, p.o.), and PLG (5, 10, and 20 mg/kg, p.o.)...
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EFFICACY OF IVERMECTIN AND DOXYCYCLINE AS AN ADJUNCT TO REMDESIVIR IN SEVERE COVID-19 CASES – A RETROSPECTIVE ANALYSIS
Introduction: Covid-19 pandemic has posed new challenges to humanity. The definitive cure is yet to be found, while drug repurposing holds the key so far. Remdesivir had been used for the treatment of novel corona-virus. Ivermectin and Doxycycline have also been recommended for treating Covid-19, but their efficacy has not been studied extensively. Methods: We conducted a retrospective study durin...
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