Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
THE REAL-WORLD STUDY OF SHENMAI INJECTION AND ITS ADVERSE REACTIONS ASSOCIATED TO PATIENTS IN CHINESE HOSPITALS: A PROSPECTIVE RESEARCH
Shenmai injection (SMI) is the Traditional Chinese Medicine Injection (TCMI) prepared by Red Ginseng and Radix Ophiopogonis extract. The aim of this study is to reveal the real-word of SMI, to evaluate its use and its adverse reactions associated to patients.A prospective, observational combined nested case-control clinical research carried out in two tertiary care teaching hospitals and two secon...
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IN-VITRO ANTIOXIDANT ACTIVITY OF SOLANUM SISYMBRIFOLIUM AERIAL PARTS
Objective: Recently, natural plants have received much attention as sources of biological active substances including antioxidants. In the present study we investigated In-vitro antioxidant activity of hexane, ethyl acetate and ethanol extracts of Solanum sisymbrifolium aerial parts. Methods: In-vitro antioxidant activity was evaluated for extracts by using free radicals Superoxide (Riboflavin pho...
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IDENTIFICATION OF NEW HIV-1 PROTEASE INHIBITORS BY MULTIPLE LINEAR REGRESSION (MLR) AND PHYSICO-CHEMICAL DESCRIPTORS
In the present work in mathematical modeling, quantitative structure activity relationship (QSAR) studies were performed on some 5,6-dihydro-2-pyrones derivativesusing statistical work.Using only 4 topological and physico-chemical molecular descriptors, we have achieved 84.81% correct classification of the compounds with and without its activity.A heurisimatedtic algorithm selects the best multipl...
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ANTIDIABETIC ACTIVITY OF HYDROETHANOLIC LEAF EXTRACT OF GYMNEMA HIRSUTUM WIGHT & ARN IN STREPTOZOTOCIN-INDUCED DIABETIC RATS
The present study has investigated the hypoglycaemic effect of oral administration of 50% ethanolic leaf extract of G. hirsutum Wight & Arn in normal and Streptozotocin–induced diabetic rats. Albino Wistar rats (190 to 220 gm) were induced diabetic condition by administration of Streptozotocin (STZ) (55 mg/kg bw) intraperitoneally. 50% ethanolic extract of G. hirsutum Wight & Arn l...
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ANTIPLATELET THERAPY AND RESISTANCE: A MINI REVIEW
Arterial thrombus formation are due to mainly platelet activation and aggregation which are considered to be central to pathological changes occurring in the vessel leading to the various complications and mortality . Antiplatelet drugs are used to prevent and help in the reversal of platelet aggregation in arterial thrombosis which was the major culprit in the pathology of myocardial infarcti...
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EXPRESSIONS PROFILING PROJECT OF HUMAN EMBRYONIC LUNG CELLSEXPOSED TO PYROLYZED CIGARETTE SMOKE
In contrast to the problematic health and economic effects of acute and chronic smoke exposure on lung function and airway inflammation, there are still few data dealing with the effects of smoking. Smoke exposurecan result in aberrant cell growth. In our experiments, pyrolyzed components of cigarettes have been shown to induce a strong stress response in cultured cells. We used human embryonic lu...
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METHOD DEVELOPMENT AND VALIDATION OF TULOBUTEROL IN API AND ITS PHARMACEUTICAL DOSAGE FORMS BY UV SPECTROPHOTOMETRY
A simple, accurate, sensitive and reproducible UV spectrophotometric method has been developed for the determination of Tulobuterol (TLB) in bulk and also in its pharmaceutical dosage formulations. The proposed method showed absorbance maxima at 212 nm. Beer's law is obeyed over a concentration range of 25-125µg/mL. The respective linear regression equation being Y =0.009x +0.014 for TLB. Results...
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1750
SYNTHESIS OF 2, 6-DIAMINO-3-PHENYLAZOPYRIDINE-1-OXIDE AND ITS HYDRO-CHLORIDE
The compound 2, 6-diamino-3-phenylazopyridine hydrochloride salt is a genito-urinary antiseptic drug under the trade name Pyridinium. This study is directed towards the occurrence of an oxidation reaction to convert the tertiary amine present in 2, 6-diamino-3-phenylazopyridine hydrochloride to form an N-oxide derivative as an impurity in the process for its preparation. This was done by the indep...
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2279
RP-HPLC METHOD FOR THE ESTIMATION OF TAMSULOSIN AND SOLIFENACIN IN BULK AND ITS DOSAGE FORMS
A liquid chromatographic method has been developed and validated for the determination of the clinical trial combination of Solifenacin succinate and Tamsulosin hydrochloride. Effective chromatographic separation was achieved on an eclipse XDB-C18 (4.6 mm X 150 mm, 5µm) column using isocratic reverse phase technique. The mobile phase employed was ACN: 20Mm sodium phosphate buffer (0.2% Triethylam...
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FORMULATION & OPTIMIZATION OF SUSTAINED RELEASE MATRIX TABLETS OF SIMVASTATIN USING RESPONSE SURFACE METHODOLOGY
The aim of the work is to formulate sustained release matrix tablets of simvastatin and to optimize them using Response Surface Methodology. The tablets were prepared by direct compression method and evaluated as per pharmacopoeia methodology. A central composite design for 2 factors at 3 levels each was employed to systematically optimize drug release profile. Concentration of HPMC K15M (X1) and ...
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