Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
CYTOGENETIC STUDY OF CHROMOSOMAL ABERRATIONS ASSOCIATED WITH CHRONIC LEUKEMIA
The most common cause of death is bone marrow failure. Chromosomal analysis is essential for the diagnosis, response to treatment and prognosis of leukemia. The present study was done to know the chromosomal abbreviation in chronic leukemia of patients with in age group of 2 to 60 years. 32 male and 21 female patients have been analyzed for this study. The chosen leukemic patients were those who w...
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SYNTHESIS, EVALUATION AND QSAR STUDIES OF SOME SUBSTITUTED PYRAZOLE DERIVATIVES
In the present paper QSAR studies related to some novel substituted pyrazole derivatives are reported. All the compounds were evaluated for antmicrobial activity viz- antifungal activity against A. niger. Their reported antimicrobial activities were used for Quantitative Structure Activity Relationship (QSAR) studies to find correlation between different calculated molecular descriptor of the comp...
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STUDY OF THE EFFECT OF SODIUM VALPROATE ON ENHANCEMENT OF MONOAMINE MEDIATED BEHAVIOURAL RESPONSES AFTER ELECTROCONVULSIVE SHOCK (ECS) ADMINISTRATION IN RATS
Objectives: To obtain the data regarding the effects of sodium valproate on enhancement of monoamines mediated behavioural responses following administration of ECS for ten days to rats. Methods: Forty rats were selected for the study in which tonic-clonic seizures were developed fully after giving single maximal electroconvulsive shock (150V, 210mA). Four groups (n= ten in each) were received dif...
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POST APPROVAL CHANGES IN BIOLOGICAL PRODUCTS
The post approval changes are the changes made to biological products that have received an approval and to provide the data to support a change which would be considered sufficient to allow a determination of the impact of the change on the quality of the approved products as it relates to safety, efficacy and/or effective use of the products. After the approval of NDA or ANDA, the applicant may ...
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NANO-THERAPEUTICS ARSENALS FOR INTERVENTION OF COLON CANCER
Nanoparticles have attracted the interest of many research groups and had been utilized in an increasing number of fields during the last decades. Various methods can be used to produce nanoparticles such as ionic gelation, solvent evaporation, microemulsion, emulsion cross linking and precipitation. This review covers the general description, preparation and the detailed description of crucial pa...
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THE SUCCESS OF DIFFERENT APPROACHES TO THE DEVELOPMENT TO ANTIPLATELET DRUGS
The aim of this research is to precisely discuss and appraise the success of different approaches to the development to antiplatelet drugs. Platelets play a main function in haemostasis and the development of arterial thrombosis that is the final event complicating cardiovascular diseases and peripheral vascular diseases, and antiplatelet drugs improve survival of patients with these diseases. Ant...
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ASSOCIATION BETWEEN ATHEROGENIC RATIO TO FASTING PLASMA GLUCOSE AND HbA1c
Hyperlipidemia is a common finding in uncontrolled Diabetes Mellitus (DM) and patients with DM generally show alteration in lipid profile, notably in triglycerides value. Research done in the past has pointed out the usefulness of Atherogenic Index of Plasma (AIP) as a useful parameter for the diagnosis of Type 2 DM. HbA1c is well established as gold standard to monitor long term diabetic control....
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A STUDY ON THE ROLE OF DIETARY AGENT MOMORDICA CHARANTIA L ON PROTEIN GLYCATION
Protein glycation is a spontaneous post translational modification of proteins by excess sugars causing formation of advanced glycation end products (AGEs) in diabetic individuals and responsible for diabetes complications. A wide variety of anti-glycating agents have been reported & recently there has been interest in natural products with anti-glycation properties. Momordica charantia L (M. ...
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EFFECT OF NUTRIENTS ON LIVER MARKER ENZYMES OF WISTAR RATS
A wide range of compounds are found to be effective against cancer for example Vitamin D3, lysine, proline, gallate, quercetin, etc. Glucosinolates from cabbage are secondary metabolites hydrolyzed by the enzyme myrosinase 1. Their breakdown products such as isothiocyanates, nitriles and thiocyanates, are chemically very reactive, and they are known for their bioactive characteristics, such as a...
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GOLD NANO-CONJUGATES: A LEAP IN CANCER TREATMENT
The use of nanoparticles as drug delivery and targeting agents has led to immense progress in the field of biomedicine and diagnostics. Likewise gold nanoparticles can be conjugated with various molecules, for instance, to plasmid DNA for gene therapy, to various drugs for antibacterial and anticancer properties, to several antibiotics and peptides for immunological and diagnostic purposes. The re...
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