Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.87 | 4.57 | 2.15 | 1.07 | 0.58 | 0.38 |
A CASE ON KAWASAKI SYNDOME IT’S DIAGNOSIS AND MANAGEMENT
Kawasaki Syndrome (KS) can be a widespread vasculitis affecting many systems, and some of the other recognized complications are discussed, including those affecting the skin, nervous system, gastrointestinal tract, musculo-skeletal system, kidneys, lungs, eyes and haematological effects. There is no specific diagnostic test or pathognomonic clinical features; those previously mentioned clinical c...
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COMPARISON OF RETABOLIL, 4-THIAZOLIDINONE DERIVATIVE (LES-2222) AND TESTOSTERONE ACTION ON THE ACTIVITY OF THE ANTIOXIDANT DEFENCE ENZYMES IN RATS UNDER FOOD DERIVATION
The manuscript devoted to investigation of some patterns of the mode of action of retabolil, compound LES-2222 (new thiopyrano[2,3-d]thiazole derivative (2-(2-Oxo-5a,11b-dihydro-5H,6H-7-oxa-1,4-dithia-3-aza-cyclopenta[c] phenanthren-3-yl)-N-(3-trifluoromethyl-phenyl)-acetamide) – synthesized at the Department of Pharmaceutical, Organic and Bioorganic Chemistry) and testosterone in rats under foo...
4873
1915
EFFECT OF AGMATINE ON 6-HYDROXYDOPAMINE INDUCED MEMORY IMPAIRMENT IN PARKINSON’S DISEASE IN RODENTS
The core finding of the present preclinical study demonstrated that, administration of increasing doses of Agmatine is remarkably neuroprotective in male wistar rats against 6-Hydroxydopamine induced neurotoxicity. Parkinson's disease (PD) is a chronic and progressive neurodegenerative disease with multiple motor and non-motor features that contribute to the impairment of health-related quality of...
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1763
SCREENING OF UNIQUE BINDING SITE SPECIFIC LIGAND FOR CARBONIC ANHYDRASE IX
Cancer is a common and widespread cause of human death in the world. Treatments like chemotherapy and radiotherapy facilitate in prolonging the patient’s life however in some cases cancer can be prevented. Cancers like breast, prostate, colon, renal cell carcinoma are caused by the overexpression of an enzyme termed Carbonic Anhydrase IX (CAIX). In 2015, 60,290 new cases of breast cancer alone a...
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1719
A CASE STUDY ON GLYCEMIC INDEX AND DIABETIC PERIPHERAL NEUROPATHY
The term HbA1c refers to glycated haemoglobin. By measuring glycated haemoglobin (HbA1c), clinicians are able to get an overall picture of what our average blood sugar levels have been over a period of weeks/months. Diabetic neuropathy is generally assessed in clinical practice by a combination of objective and subjective measures. Nerve conduction studies, the distal sural sensory nerves and the...
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1614
BIO EFFICACY OF MICHELIA CHAMPACA LINN ON MEMBRANE BOUND ENZYMES IN CCl4 INDUCED HEPATOTOXICITY IN RATS
The aim of the present study is to evaluate the protective effect of flower extract of Michelia champaca on membrane bound enzyme (serum ATPase) levels on male albino rats. The membrane bound enzymes (Ca2+ ATPase, Mg2+ ATPase, Na+K+ ATPase) levels of methanolic flower extract of Michelia champaca at a dose of 300 mg/kg was evaluated during exposure to CCl4. There was a significant decrease i...
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SYNTHESIS AND CHARACTERIZATION OF [16]-MEMBERED DIOXA DIAZA NAPTHALDEHYDE BASED MACROCYCLIC LIGAND AND ITS COMPLEXES OF Co(III), Ni(II) AND Cu(II) PERCHLORATE IONS
An hitherto new unreported [16]-membered dioxadiazanapthaldehyde based macrocyclic ligand (L) 2,11-dioxa-23,30-diaza heptacyclo [30.4.0.0 4, 9.0 12, 21. 0 14, 19. 0 24, 29. 0 34, 39]-tetraconta-12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, 38, 40-pentadecaene, has been synthesized by two different synthetic routes each involving two stages. 2-Hydroxy-1-Napthaldehyde in the presence of potass...
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1592
EFFECT OF AZADIRACHTA INDICA ON HYPERGLYCEMIA INDUCED OXIDATIVE STRESS IN ALLOXAN DIABETIC RAT BRAIN
The present study evaluates antidiabetic effect of A. indica leaf extract (AILE) and A. indica bark extract (AIBE) on antioxidant enzymes in the brain of alloxan diabetic rats and compared with insulin treatment. The oral effective dose of A. indica leaf (500mg/Kg body weight) and A. indica bark (100mg/Kg body weight) was given once daily for 21days to separate groups of diabetic rats. At the end ...
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1677
FORMULATION AND IN-VITRO EVALUATION OF FLOATING EFFERVESCENT TABLETS OF RANITIDINE HYDROCHLORIDE
The main objective of the present work is to develop Floating Effervescent matrix tablets of Ranitidine hydrochloride using different polymers viz. hydroxy propyl methyl cellulose (HPMC), Xanthan gum and Guar gum. Varying ratios of drug and polymer like 1:0.6 and 1:1 were selected for the study. After fixing the ratio of drug and polymer for control the release of drug up to desired time, the rele...
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IN-VITRO ANTI-INFLAMMATORY ACTIVITY OF SELECTED DIHYDROXY FLAVONE BY TPA INDUCED INFLAMMATION IN POLYMORPHONUCLEAR LEUCOCYTES
The present study involves the investigation of anti-inflammatory activity for 2’, 4’ dihydroxy flavone by TPA [12- O- Techanoyl 13 – Myristate] induced inflammation in Polymorphonuclear leukocytes [PMNL]. The cell viability was assayed by Trypan blue dye exclusion assay, MTT assay, release of Cathepsin D, Nitrite and TNF-α levels. Diclofenac sodium was used as the standard drug. The select...
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