Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.87 | 4.57 | 2.15 | 1.07 | 0.58 | 0.38 |
DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR QUANTIFICATION OF BETULINIC ACID IN VITEX NEGUNDO L. AND ITS POLYHERBAL FORMULATIONS
The Vitex negundo, which is traditional Indian medicine, has been used for treatment of various diseases. A simple, sensitive, precise and accurate RP-HPLC method has been developed for the analysis of Vitex negundo L. samples and its polyherbal formulations for their Betulinic acid content. The extraction was checked using different solvents like methanol, chloroform, 95% ethanol, acetone and dic...
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SATURATION SOLUBILITY OF SCOPOLAMINE IN THIN FILMS OF POLYACRYLATE PRESSURE SENSITIVE ADHESIVES IS TEMPERATURE DEPENDENT
The method of drug uptake from solid solution has been used to measure the saturation solubility of scopolamine base in various pressure sensitive adhesive DURO-TAKs at elevated temperature. The saturation solubility was strongly temperature dependent, being 50 – 100 % larger at 45°C than at 25°C. The higher temperature also caused much more rapid approach to equilibrium distribution of the dr...
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TOXICOLOGICAL CHRACTERIZATION OF BRHANMANJISTHADI KVATHA CURNA (BRH) ON THE BASIS OF TOTAL PROTEIN AND ALBUMIN CONTENT, LIPID PROFILE, LIVER FUNCTION, KIDNEY FUNCTION, SERUM URIC ACID AND ENZYMATIC PROPERTY IN RATS’ PLASMA AFTER CHRONIC ADMINISTRATION
Brhanmanjisthadi Kvatha Curna (BRH) an Ayurvedic preparation, is used as a traditional medicine in filariasis in the northern part of the country. After 45 consecutive days of chronic administration of the BRH preparation in rats its toxicological aspects was studied. In the study the total protein content in the plasma was increased (2.80 %) in BRH treated male rats in comparison to their control...
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A PILOT STUDY TO ASSESS THE EFFICACY AND SIDE EFFECTS OF SILYMARIN ALONE AND IN COMBINATION WITH ALENDRONATE IN TREATMENT OF POSTMENOPAUSAL OSTEOPOROSIS
Background: Currently oral bisphosphonates such as alendronate are the preferred therapeutic option for the treatment of postmenopausal osteoporosis by increasing bone mineral density and decreasing both vertebral and non-vertebral fracture risk. Silymarin is mainly used as hepato-protectant but in recent studies on ovariectomized rats, it was found that silymarin can be a promising antiosteoporot...
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3D-QSAR STUDY OF BENZOTHIAZOLE DERIVATIVES AS p56lck INHIBITORS
3D-QSAR models of Comparative of Molecular Field Analysis (CoMFA) and Comparative of Molecular Similarity Indices Analysis (CoMSIA) of 44 potent p56lck inhibitors were performed. The conventional ligand-based 3D-QSAR studies were performed for a series of Benzothiazole derivatives as p56lck inhibitors. The model gave q2 values of 0.710 and 0.642, r2 values of 0.966 and 0.956 for CoMFA and CoMSIA, ...
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3D-QSAR STUDY OF BENZOTHIAZOLE DERIVATIVES AS p56lck INHIBITORS
3D-QSAR models of Comparative of Molecular Field Analysis (CoMFA) and Comparative of Molecular Similarity Indices Analysis (CoMSIA) of 44 potent p56lck inhibitors were performed. The conventional ligand-based 3D-QSAR studies were performed for a series of Benzothiazole derivatives as p56lck inhibitors. The model gave q2 values of 0.710 and 0.642, r2 values of 0.966 and 0.956 for CoMFA and CoMSIA, ...
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2045
THE ROLE OF LAB-ON-A-CHIP DEVICE IN HEALTH CARE
Lab-on-a-chip (LOC), a scaled down microfluidic device for carrying out laboratory operations outside the scope of standard laboratories is a rather appealing development in the field of science and technology for the whole laboratory has been reduced to a small chip capable of carrying out various functions. Keeping to its word, micro, miniaturized volume samples and reagents has ebbed the time t...
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SULFONIC ACID COUNTER IONS QUANTIFICATION IN PHARMACEUTICALS BY ION CHROMATOGRAPHY
The present paper deals with the analysis of methane sulfonic acid, benzene sulfonic acid and camphor sulfonic acid counter anions in pharmaceutical ingredients (doxazosin mesylate, amlodipine besylate and clopidogrel camphor sulfonate) by suppressed conductivity anion chromatography. The diluent used for the preparation of sample solution was Milli-Q Water and injected into a standard chromatogra...
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CYTOGENETIC STUDY OF CHROMOSOMAL ABERRATIONS ASSOCIATED WITH CHRONIC LEUKEMIA
The most common cause of death is bone marrow failure. Chromosomal analysis is essential for the diagnosis, response to treatment and prognosis of leukemia. The present study was done to know the chromosomal abbreviation in chronic leukemia of patients with in age group of 2 to 60 years. 32 male and 21 female patients have been analyzed for this study. The chosen leukemic patients were those who w...
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SYNTHESIS, EVALUATION AND QSAR STUDIES OF SOME SUBSTITUTED PYRAZOLE DERIVATIVES
In the present paper QSAR studies related to some novel substituted pyrazole derivatives are reported. All the compounds were evaluated for antmicrobial activity viz- antifungal activity against A. niger. Their reported antimicrobial activities were used for Quantitative Structure Activity Relationship (QSAR) studies to find correlation between different calculated molecular descriptor of the comp...
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