Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
STUDY OF THE EFFECT OF MELATONIN ON RETENTION OF CONDITIONED AVOIDANCE RESPONSE AND ON ENHANCEMENT OF SEROTONIN MEDIATED BEHAVIOURAL RESPONSES AFTER ELECTROCONVULSIVE SHOCK (ECS) ADMINISTRATION IN RATS
Objectives: To obtain the data regarding the effects of melatonin on retention of conditioned avoidance response (CAR) and on enhancement of serotonin mediated behavioural responses after electroconvulsive shock (ECS) administration in rats. Methods: Forty rats after training for conditioned avoidance response by using Cook’s pole climbing apparatus were divided in four groups with ten rats in e...
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ANTIBIOTIC DE-ESCALATION IN THE INTENSIVE THERAPY UNIT- A REVIEW
An antibiotic may be defined as a substance or compound that kills or inhibits the growth of, bacteria. Antibiotics belong to the broader group of antimicrobial compounds, used to treat infections caused by microorganisms, including fungi and protozoa, viruses. Antibiotic de-escalation is a mechanism whereby the provision of effective initial antibiotic treatment is achieved while avoiding unneces...
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2087
EFFECT OF INGREDIENTS OF A LOCAL ANTIDIABETIC FORMULATION IN ENHANCING THE ANTIDIABETIC ACTIVITY OF SALACIA RETICULATA IN ALLOXAN INDUCED DIABETIC RATS
Salacia reticulata, used in traditional and local medicines in Western Ghats of Southern India for the treatment of hyperglycaemia, is widely used for its sugar lowering activity. Accordingly, the present study was designed to investigate the possible actions of ethanolic extract of roots of Salacia reticulate (EESR) and an ethanolic extract of local formulation (EELF) made by mixing roots of Sala...
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2323
DIFFERENCE BETWEEN NATIVE AND MUTANT RHIZOBIUM ON GROWTH OF VIGNA MUNGO L.
The present study, carry out the use of plant growth promoting rhizobacteria, were used to improve the yield in crop. The Rhizobium strains isolated from legumes plant Mimosa pudica L and this strain was mutated by using UV radiation. The plant growth hormones were detected by native as well as mutant Rhizobium strains by paper chromatography techniques. The same strains use in conducted to green ...
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1668
THE EFFECT OF PURIFIED NIGELLA SATIVA LECTIN AGAINST TUMOR DEVELOPMENT IN FEMALE ALBINO MICE AND GENETIC POLYMORPHISM IN PUMA GENE
The purpose of this study examine whether the polymorphism in p53 upregulated modulator of apoptosis (PUMA) gene consequential treated with purified Nigella sativa lectin in tumor induced mice. Nigella sativa (N. sativa) is a widely used medicinal plant throughout the world. Possess a seed lectin that was purified by combination of ammonium sulfate precipitation and affinity chromatography on a Se...
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STUDY OF THE INVOLVEMENT OF ADIPONECTIN AND HOMA-IR IN TUNISIAN SUBJECTS WITH METABOLIC SYNDROME
Metabolic syndrome (MS) is a multi-factorial disorder with insulin resistance as a major characteristic. Adiponectin, an adipocyte derived cytokine, can regulate glucose levels and lipid homeostasis by its insulin sensitizer properties. Low circulating levels of serum adiponectin has been reported as a risk factor for the development of MS. The aim of this case control study was to investigate the...
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1537
EFFECT OF GLY 16 ARG SINGLE NUCLEOTIDE POLYMORPHISM ON AGONIST BINDING TO BETA 2 ADRENERGIC RECEPTOR – A STRUCTURAL PHARMACOGENOMIC APPROACH
Asthma is obAdd Newstructive disease characterized by bronchoconstriction and inflammation for which beta 2 (β2) agonists that act through the β2 adrenoceptor are the first line agents of choice. Glycine16Arginine (Gly16Arg) is a common single nucleotide polymorphism (SNP) of β2 adrenoceptor whose effects on treatment response remain inconclusive. Hence the study aims to understand and determin...
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1734
COMPARATIVE MODELING OF INACTIVE UBIQUITIN THIOESTERASE FAM105A AND MOLECULAR DOCKING STUDIES OF SYNTHESIZED BENZIMIDAZOLE DERIVATIVES
In this study, homology modeling and molecular docking studies were performed to explore structural features and binding mechanism of synthesized benzimidazole derivatives as ubiquitin inhibitors. A homology modeling procedure was employed to construct a 3D model of ubiquitin protein by using MODELLER9.15. For this procedure, the X-ray crystal structure of Gumby / fam105b in Complex with linear Di...
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1680
SOLUBILITY ENHANCEMENT AND DEVELOPMENT OF DISPERSIBLE TABLET OF CANDESARTAN CILEXITIL
Candesartan Cilexitil is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. Candesartan cilexitil is a BCS class II drug having low solubility and high permeability. Candesartan Cilexitil is a prodrug which is rapidly converted to the active drug, Candesartan, by ester hydrolysis during absorption from the gastrointestinal tract. The bioavailability of Candesartan...
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SOLUBILITY ENHANCEMENT AND DEVELOPMENT OF DISPERSIBLE TABLET OF CANDESARTAN CILEXITIL
Candesartan Cilexitil is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. Candesartan cilexitil is a BCS class II drug having low solubility and high permeability. Candesartan Cilexitil is a prodrug which is rapidly converted to the active drug, Candesartan, by ester hydrolysis during absorption from the gastrointestinal tract. The bioavailability of Candesartan...
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