Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
DEVELOPMENT AND VALIDATION OF NOVEL RP- HPLC METHOD FOR SIMULTANEOUS ANALYSIS OF PREGABALIN AND DULOXETINE IN SYNTHETIC MIXTURE
A sensitive, rapid, precise and accurate RP-HPLC method was developed for simultaneous estimation of Pregabalin and Duloxetine in synthetic mixture. To introduce a chromophoric group in Pregabalin structure, derivatization was carried out through benzoylation reaction. RP- HPLC method is carried out using Hypersil BDS column C18 (250 cm × 4.6 cm, 5 μm). Mobile phase used as combination of Methan...
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TERATOGENIC EFFECT OF DRUGS AT DIFFERENT STAGES OF PREGNANCY
Objective: Teratogens play a crucial role in the 4-5% of infants who are born with physical or functional abnormalities in this world. Teratogens are recognized for their capacity to harm fetuses or neonates. Observations: Pregnancy-related exposure to certain substances may result in birth abnormalities or malformations of the fetus, such as behavioral or emotional problems, low IQ, physical defo...
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EFFECT OF MUSIC THERAPY IN PATIENTS UNDERGOING CAESAREAN DELIVERY UNDER SPINAL ANAESTHESIA
Background: Increased anxiety in patients undergoing caesarean delivery has a negative impact on fetus and mother. Music therapy can have beneficial effects. The aim of our study was to determine the effects of preoperative and intraoperative music therapy on anxiety, pain, patient satisfaction and postoperative nausea and vomiting in patients undergoing caesarean delivery under spinal anaesthesia...
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EVALUATION OF IN-VIVO ANTI-INFLAMMATORY ACTIVITY OF MONO HERBAL SIDDHA FORMULATION KANDUPARANGI CHOORANAM (PYGMAEOPREMNA HERBACEA – ROOT POWDER) IN CARRAGEENAN-INDUCED PAW EDEMA & PLEURISY IN WISTAR ALBINO RATS
Introduction: Monoherbal or polyherbal formulation, which is used in Siddha medication, have a wide variety of phytochemical substances as primary and secondary metabolites, which show many pharmacological activities, including the anti-inflammatory effect. Materials and Methods: The anti-inflammatory activity of Kanduparangi chooranam (KC) was evaluated by using carrageenan-induced paw edema and ...
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COMPARISON OF BACTEC VERSUS CONVENTIONAL METHOD FOR CULTURE OF STERILE BODY FLUIDS IN A TERTIARY CARE HOSPITAL
Aim & Background: Body fluids are sent to clinical microbiology laboratory for culture to find the etiological agent causing the infection. This study was conducted to compare the culture results of sterile body fluids processed simultaneously by both conventional method and BACTEC blood culture system. Methods: Sterile body fluids except blood were included in the study. A total of 61 body fl...
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DEVELOPMENT OF pH-INDEPENDENT MUCOADHESIVE PELLETS FOR EFFECTIVE TREATMENT OF VAGINAL CANDIDIASIS
Objective: The present investigation aims to develop pH-independent mucoadhesive pellets using the extrusion-spheronization procedure and the inter-polyelectrolyte complex (IPEC) of Chitosan-Carbopol 71G. Miconazole was used as a representative drug in this study. Materials and Method: It was found that the composition of the formulation impacts the extrusion of the prepared dough mass. The genera...
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PHYTOCHEMICAL SCREENING AND ANTIOXIDANT POTENTIAL OF SELECTED CHENOPODIUM SPECIES
Chenopodium album, Chenopodium murale, and Chenopodium giganteum are annual herb. Almost 250 different species of Chenopodium can be found all over the world. They are grown for many purposes, including some for their green leafy vegetables and others for the grains they provide. The phytochemicals, proteins, carbohydrates, tannins, flavonoids, alkaloids, steroids, terpenoids, and saponins have at...
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EVALUATION OF ENDOCAN AND ENDOGLIN AS PREDICTIVE MARKERS OF ENDOTHELIAL DYSFUNCTION IN WISTAR ALBINO RATS TREATED WITH A SINGLE DOSE OF STZ AND HFD
A major susceptibility indicator for type 2 diabetes and cardiovascular diseases is obesity-related insulin resistance. Vascular endothelial cells strongly express the coreceptors for members of the transforming growth factor (TGF) superfamily, endocan and endoglin. Examining endocan and endoglin as potential indicators of cardiovascular complications in HFD rats with or without type 2 diabetes me...
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FORMULATION AND EVALUATION OF BUTENAFINE HYDROCHLORIDE LOADED CUBOSOMAL GEL
The aim of this research was to develop and evaluate a cubosomal gel for the treatment of skin diseases such as athlete's foot (tineapedis), ringworm (tineacruris) and ringworm (tineacorporis). To increase the penetration of the drug and to provide longer duration of treatment this study was performed. Cubosomes are a novel nanoparticle system loaded with butenafine hydrochloride as an antifungal ...
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EVALUATION OF ANTICANCER POTENTIAL OF METHANOLIC EXTRACT OF PETALS OF CHRYSANTHEMUM MORIFOLIUM AGAINST HUMAN LIVER CANCER CELL LINE (HEPG2)
Chrysanthemum morifolium is commonly known as chrysanthemum. It has been widely used in traditional medicine due to its various therapeutic effects. Past studies have shown that chrysanthemum extracts possess significant anticancer activity against breast, prostate, and colon cancer cells. The active compounds in chrysanthemum extracts such as flavonoids, sesquiterpenes, and triterpenoids have bee...
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