Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
PHYTOCHEMICAL SCREENING AND GC-MS ANALYSIS OF BIOACTIVE COMPOUNDS FROM PINDA CONCANENSIS
The plant Pinda concanensis belongs to family apiaceae. It was native to the Western Ghats of India, but it is now becoming rare as a result of widespread usage of the seeds for their therapeutic properties. It is an annual herb with tuberous roots, which are eaten raw by local folklore. Apiaceae is the well-known aromatic plant family having beneficial uses in home remedies, abundance of phytoche...
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CHARACTERIZING THE ADIPOKINES, INFLAMMATORY CYTOKINES RESPONSE IN ENDOTHELIAL DYSFUNCTION IN HIGH-FAT DIET AND SINGLE DOSE OF STZ IN WISTAR ALBINO RAT MODELS
Introduction: Endothelial dysfunction and diet-induced diabetes may be significantly impacted by changes in Adipokine and inflammatory cytokine secretion linked to obesity. Our study's objective was to determine the effect of a high-fat diet also on concentrations of leptin, adiponectin, as well as other inflammatory indicators in type 2 diabetes mellitus brought on by streptozotocin (STZ)-induced...
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EVALUATION OF BINDING AFFINITY OF THE SELECTED HERBAL BIO-ACTIVE COMPONENTS WITH THE ENZYME CYP- 17Α-HYDROXYLASE BY PCOS AMELIORATION ACTIVITY THROUGH MOLECULAR DOCKING IN- SILICO APPROACH
Polycystic ovarian syndrome (PCOS) known by its name can be correlated with Soothaga Vaayu in Siddha classical literature which is one of the most common forms of metabolic and endocrine disorders of women, with a high prevalence among the reproductive age group, often associated with obesity, hypertension, insulin resistance, diabetes mellitus, hyperinsulinemia and dyslipidemia. Current therapeut...
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HYDROGEN PEROXIDE SCAVENGING ACTIVITY OF OXAZOLE DERIVATIVES
The present study is reported the antioxidant activity of oxazole derivatives. Oxazole are five-member heterocyclic ring containing nitrogen and oxygen as a hetero atom. Due to binding with a wide spectrum of receptors and enzymes easily in biological systems through various non-covalent interactions, oxazole-based molecules are becoming a kind of significant heterocyclic nucleus, which have recei...
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PHARMACOGNOSTIC AND HPTLC COMPARISON OF KERALA MARKET SAMPLES OF BHARANGI (CHERUTHEK) WITH GENUINE SOURCE PLANT ROTHECA SERRATA (L.) STEANE & MABB
Background: Bhāraṅgī, herbal drug used in Ayurveda as Kapha-Vata samaka and indicated in Swasa, Kasa, Vrana, Shotha etc. It is an important ingredient in many of the preparations like Kantakaryavaleha, Kanakasava, Dasamularista, Lodhrasavam, Sudarsanasavam. As per API the accepted source of Bhāraṅgī is Rotheca serrata (L.) Steane & Mabb belongs to family Lamiaceae. There were ambient s...
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IDENTIFYING TUBULIN AS A NEW TARGET OF A DIHYDROPYRIDINE DERIVATIVE, AMLODIPINE BESYLATE
The quest for new antimitotic drugs is an ongoing process where microtubules act as an attractive target for anti-cancer drugs. In this work, we report on the anti-cancer activity of Amlodipine besylate (AB), a salt derivative of the dihydropyridine groupdrug Amlodipine, a long-acting third-generation calcium channel blocker. Cytotoxicity assay revealed that AB demonstrated cytotoxic effects again...
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A RETROSPECTIVE COMPARATIVE STUDY OF TOXICITIES AND OUTCOMES BETWEEN GEMCITABINE + NAB PACLITAXEL AND FOLFIRINOX IN LOCALLY ADVANCED CA PANCREAS RECEIVING IN NEO-ADJUVANT CHEMOTHERAPY
Neoadjuvant chemotherapy with Gemcitabine/nab-paclitaxel (Gemcitabine + Nab-Paclitaxel) And Folfirinox (Folfirinox) are two standard therapies for patients who has locally advanced pancreatic cancer (Lapc). We retrospectively compared the efficacy and safety of the two treatment regimens in patients with unresectable pancreatic cancer. The sample size consisted of 96 patients who has locally advan...
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HOMOEOPATHIC MANAGEMENT OF AN ACUTE CASE OF CERVICAL SPONDYLOSIS: A CASE REPORT
Introduction: Cervical spondylosis is a degenerative spine disorder commonly affecting the vertebrae and intervertebral discs in the cervical region. Most people commonly present with the complaint of neck pain at least once in their lifetime. It is, therefore, important to ascertain the cause responsible for it. Homoeopathy has a great scope in relieving the pain caused due to spondylosis, thereb...
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ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF UV-VISIBLE SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF CLIMBAZOLE
Climbazole is a topical antifungal agent commonly used to treat human fungal skin infections such as dandruff and eczema. The goal of research work was to develop and validate a simple, precise, quick, and highly efficient UV spectrophotometric approach for quantifying Climbazole in bulk and shampoo dosage form. The quantification was completed using a twin beam UV spectrophotometer at 222 nm and ...
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PRIMARY AMENORRHEA WITH APLASTIC UTERUS, BILATERAL NON-COMMUNICATING RUDIMENTARY HORNS WITH HEMATOMETRA IN LEFT HORN AND CERVICOVAGINAL APLASIA (U5A C4 V4) – A RAREST CASE REPORT
Congenital uterine malformations account for 5.5 % of unselected population, while mullerian agenesis has an incidence of 1 in 4500-5000 females. Mullerian agenesis occurs due to embryological underdevelopment of mullerian duct with resultant agenesis or atresia of the vagina, uterus or both. We report a rare case of 22 year old female with primary amenorrhea with aplastic uterus with bilateral ru...
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