Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
FAST DISSOLVING TABLETS: A REVIEW
For treatment or management of diseases, oral delivery is giving much more attention from the ancient decade. A new concept in oral delivery is mouth dissolving tablets (MDTs) are widely accepted nowadays. Mouth dissolving tablets are solid dosage forms which, when placed in the mouth, disintegrate, dissolve and release active agent within a few minutes without the need for water. It has more sign...
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USING OF INFORMATIONAL PARAMETERS AS A CRITERION FOR DETERMINING THE EFFECTIVENESS OF BIOSTIMULATION WITH USE OF TISSUE PREPARATIONS
Possibility of use of the informational parameters, which characterize adaptational and regenerative opportunities of organ, as potential criteria for the assessment of biological activity of tissue preparations, is investigated in this research. The influence of tissue preparation «STEMB» on the morphofunctional condition of a liver of rats at experimental toxic damage of organs was studied. Th...
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IN-VITRO ANTIOXIDANT AND IN-VIVO HEPATOPROTECTIVE ACTIVITY OF GANODERMA LUCIDIUM STRAINS DARL-4 & MS-1 AGAINST PARACETAMOL INDUCED HEPATOTOXICITY
The purpose of current research work is to evaluate the in-vitro antioxidant and in-vivo hepatoprotective activity of Ganoderma lucidum strains DARL-4 and MS-1. Antioxidant activity of different extracts was evaluated by using DPPH and ABTS method. Hepatoprotective activity of hydroalcoholic extract of G. lucidum strain DARL-4 and MS-1 were evaluated by paracetamol-induced liver damage in rats. Th...
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MICROWAVE INDUCED SOLUBILITY ENHANCEMENT OF POORLY WATER SOLUBLE DRUG SIMVASTATIN USING POLOXAMER 188 BY MICROWAVE IRRADIATION METHOD
To increase the solubility of poorly water-soluble drug simvastatin using hydrophilic carrier poloxamer 188 using solid dispersion techniques by microwave irradiation method. The microwave irradiation technique was used to prepare solid dispersions in minimum time interval in different drug carrier ratios, i.e. 1:2, 1:5, 1:8 and was subjected to microwave for different times, i.e. 3 min, 5 min, an...
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A NEW VALIDATED STABILITY INDICATING RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF GRAZOPREVIR AND ELBASVIR IN TABLET DOSAGE FORMS
A combination of Grazoprevir and Elbasvir is used to treat Hepatitis C virus (HCV). A selective, accurate and precise RP-HPLC method was developed and validated for the simultaneous estimation of these drugs in combined tablet dosage forms. The drugs were resolved on a BDS C18 column using 0.1% orthophosphoric acid: Acetonitrile (45:55 v/v) as the mobile phase. The detection wavelength was 260 nm....
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UPLC STABILITY INDICATING METHOD FOR SIMULTANEOUS ESTIMATION OF GLECAPREVIR AND PIBRENTASVIR
A forced stability-indicating method for simultaneous estimation of glecaprevir and pibrentasvir by Ultra Performance Liquid Chromatography (UPLC) was developed and validated. The separation was done on column BEH C18 50 × 2.1mm 1.7m which was maintained at 30 °C, eluted with isocratic mobile phase and eluents were detected at 260nm. Mobile phase containing Buffer 0.01NKH2PO4: Acetonitrile taken...
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DEVELOPMENT OF ANALYTICAL METHOD FOR SIMULTANEOUS ESTIMATION OF AMOXICILLIN AND CARBOCISTEINE IN SOLID DOSAGE FORM BY RP-HPLC
Pharmaceutical analysis is the application of principles of analytical chemistry to drug analysis. The analytical chemistry is the science of developing accurate, precise, and sensitive methods for determining the composition of materials in terms of elements or compounds which they contain. Quality means confirming specifications and standards, and it is never an accident; it is a result of intel...
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IDENTIFICATION, QUANTITATIVE DETERMINATION AND ANTIDEPRESSANT ACTIVITY OF CHLOROGENIC ACID AND GALLIC ACID FROM MORUS ALBA LEAVES
Objective: The present study is considered to estimate preliminary phytochemical components, physicochemical parameters, HPTLC chromatographic studies and antidepressant activity of chlorogenic acid & gallic acid present in extracts of Morus alba leaves. Methods: Total phenol content, total flavonoid content, total tannin content, HPTLC fingerprinting analysis for compounds like chlorogenic ac...
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THE RELATIONSHIP BETWEEN CLINICAL FEATURES AND MAGNETIC RESONANCE IMAGING PROVED LUMBAR DISC BULGING AND HERNIATION
Background: Lumbar disc herniation is one of the commonest causes of low back pain. The magnetic resonance imaging is a gold standard non-invasive investigation for viewing lumbar anatomy in detail. Aim of the Study: To evaluate the effects of body mass index on the presence, extent and severity of lumbar disc bulging and herniation as well as to determine the relationship between clinical feature...
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A HPTLC DENSITOMETRIC METHOD FOR THE DETERMINATION OF β -SITOSTEROL IN PERGULERIA DAEMIA LEAF AND STEM EXTRACT
HPTLC is a simple, rapid, precise and accurate method with densitometric detection for the determination of beta-sitosterol in a Pergularia daemia Forsk. Petroleum ether and methanol extract of the leaf and stem were powder and used for the experimental work. The separation was performed on silica gel 60 F254 HPTLC plates with Toluene: Ethyl acetate (80:20 v/v), as the mobile phase. The determinat...
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