Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF NOVEL5, 6-DIHYDRO-3-(SUBSTITUTED PHENYL) [1, 2, 4] TRIAZOLE (3, 4-B) [1, 3, 4] THIADIAZINE-7-ONE DERIVATIVES FOR ANTIMICROBIAL AND FREE RADICAL SCAVENGING ACTIVITY
The present research aims to synthesize novel 5, 6-dihydro-3-(substituted phenyl) [1, 2, 4] triazolo (3, 4-b) [1, 3, 4] thiadiazine-7-one derivatives and their physiochemical evaluation for antibacterial and antioxidant activities. Novel synthetic schemes were designed to synthesize compounds (1-6), which were then characterized using physicochemical and spectroscopic methods (IR, 1HNMR). In-vitro...
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DESIGN, DEVELOPMENT AND STATISTICAL OPTIMIZATION OF ACYCLOVIR-LOADED PROTEIN NANOPARTICLES
To solve the problem of low drug availability in the body, acyclovir was fabricated into biodegradable gelatin nanoparticles by step-wise two-times desolvation method where gelatin was used as biodegradable polymer and glutaraldehyde was utilized as a cross-linking agent. Optimization was conceded by design expert computational application whereby the outcome of gelatin polymer concentration (X1...
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SOLUBILITY ENHANCEMENT AND QUALITY BY DESIGN (QBD) ASSISTED FABRICATION OF FAST DISSOLVING BUCCAL FILM FOR RISPERIDONE
Rapidly Dissolving Drug Delivery Systems have become interested in the pharmaceutical industry as frameworks that provide quick onset of action with enhanced dissolution characteristics. Risperidone, a poorly water-soluble drug, is a second-generation antipsychotic of the benzisoxazole derivatives used in treating schizophrenia and other mood disorders. The present research work aimed to fabricate...
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THE METHANOLIC EXTRACT OF ALBIZIA ODORATISSIMA BARK ATTENUATED THE DEVELOPMENT OF DIABETIC NEPHROPATHY IN RATS
Purpose: The present study has been designed to investigate the protective effect of methanolic extract of Albizia odoratissima (AO) bark in prevention of streptozotocin (STZ) induced-diabetic nephropathy (DN) in Wistar rats. Methods: Healthy Wistar rats of either sex weighing 180-200g were employed in the present study. Experimental diabetes was induced in rats by injecting STZ at a dose of 45 mg...
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SQUALENE: A POTENTIAL ANTI-ALZHEIMER’S COMPOUND IN ALBINO RAT
Alzheimer’s disease, the most scattered neurodegenerative disease causes progressive destruction in serviceable performances and continuous reduction in cognitive activities and memory in aged people. It is estimated that people suffering from AD is about 10% between 65-70 years and 50% in people above 85years of age and this number will double every two decades. Even though extensive research h...
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FORMULATION AND EVALUATION OF LIQUID-FILLED HARD GELATIN CAPSULE OF DICLOFENAC POTASSIUM
Background Diclofenac Potassium is the potassium salt form of diclofenac, a benzene acetic acid derivate, and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity. Aim: Therefore, the purpose of the present study was to formulate and evaluate liquid-filled hard gelatin capsules of diclofenac potassium. Methods: The liquid-filled soft gelatin c...
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CERIUM OXIDE NANOPARTICLES APPLICATIONS IN THE FIELD OF CARDIOVASCULAR DISEASES
Cardiovascular disease (CVD) is the sixth most common human disease that causes about 17.3 million deaths yearly. Advancement in nanomedicine enables the usage of nanomaterials for treating cardiac disorders. Among these, Cerium Oxide (CeO2) nanoparticle is gaining attention due to their irreversible oxidative states (Ce3+ and Ce4+), which provide them with many unique, physiologically important t...
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SEMECARPUS ANACARDIUM LINN: AN ETHNOMEDICAL, PHYTOCHEMICAL AND PHARMACOLOGICAL REVIEW
Semecarpus anacardium Linn. (Family Anacardiaceae), generally known 'Ballataka' or' Bhilwa', is a factory well-known for its medicinal value in ayurvedic and siddha system of the drug; it's also used for non-medicinal purpose like marking of cloth, hair color, etc. since ancient time. Phytochemical analyses of Semecarpus anacardium nut shows that, its nut contains a variety of biologically active ...
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NANOSTRUCTURED LIPID CARRIERS: THE ADVANCED LIPID CARRIERS AND THEIR APPLICATIONS
Nanostructured Lipid Carriers (NLCs) is a novel type of drug-delivery system. They are binary system which is stable in a different environment. Nanostructured Lipid Carrier (NLC) comprises a blend of solid and liquid lipids as a core matrix. NLCs have aggravated the incessant impulsion for developing safe and valuable drug delivery systems due to their exceptional physicochemical and biocompatibl...
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SELF-MICROEMULSIFYING DRUG DELIVERY SYSTEM: SPECIAL EMPHASIS ON VARIOUS OILS USED IN SMEDDS
In pharmaceuticals formulation, poorly aqueous soluble medications are becoming more difficult to administer into dosage form as 40-50% of new chemical entities discovered are reported to be poorly aqueous soluble, preventing appropriate absorption from the GI tract. Oral administration is preferred over other forms of administration due to its ease of administration & painless approach. The m...
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