Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
ORAL STRIPS: A NOVEL DRUG DELIVERY TECHNOLOGY
In the development of a new drug molecule, there are many problems with respect to the dissolution, absorption, and bioavailability. Thus, formulation scientists are majorly focusing on the development of the formulation, which will increase the efficacy of the existing drugs. Oral dispersible films are one of such a novel approach. In given review article, the advantages of oral dispersible films...
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PHARMACOLOGICAL ACTIVITIES OF MUNTINGIA CALABURA: AN OVERVIEW OF THE LAST LUSTRUM
Background: In honor of a dutch botanist, Abraham Munting, the tree was named Muntigia calabura L. The Jamaica cherry, M. calabura is a shrub or tree which is native to Jamaica, Brazil, Mexico, and North America. M. calabura is a well-known, fast-growing tree clasped with different medicinal and health benefits. Different parts of the tree are being used for various ailments in different parts of ...
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NOVEL STRATEGY FOR IMPROVING BIOAVAILABILITY OF OCULAR DRUG DELIVERY USING COLLOIDAL NANOSUSPENSION
Nowadays, a very large proportion of new drug candidates arising from drug discovery programs are water-insoluble and, for that reason, poorly bioavailable. The trouble is even more complex for drugs that belong to the BCS Class II category. To overcome these problems, nanotechnology is used to enhance the solubility as well as bioavailability of poorly soluble drugs. In the ocular drug transport ...
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HEPATOPROTECTIVE EFFECT OF EUGENIA UNIFLORA ACTIVE FRACTION AGAINST CCL4 INDUCED HEPATOTOXICITY IN MALE WISTAR RATS
Eugenia uniflora known as pitanga or Surinam cherry, belongs to the Myrtaceae family and has essential nutrients that are prerequisites for human health. In the present study, Eugenia uniflora active fraction (EF18) that was obtained from the partial purification of crude ethanolic extract of Eugenia uniflora leaves were evaluated for its carbon tetrachloride (CCl4) induced liver toxicity in rats....
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DISEASE MODIFYING POTENTIAL OF WEDELOLACTONE RICH FRACTION OF ECLIPTA ALBA IN ADJUVANT INDUCED ARTHRITIS IN RATS BY INHIBITION OF PRO-INFLAMMATORY CYTOKINES
Eclipta alba (Family-Asteraceae) is a herb commonly used in traditional Ayurvedic medicine for the treatment of inflammation, pain, and wounds. The present study is aimed to validate the ethnobotanical use of Eclipta alba in an animal model. The animals were induced with arthritis by injection of FCA on day 0 and treated with wedelolactone rich fractions of Eclipta alba (100, 200 and 400 mg/kg) fr...
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ANTIDIABETIC EFFECT OF ETHANOLIC LEAVES EXTRACTS OF AZIMA TETRACANTHA LAM. IN STREPTOZOTOCIN INDUCED DIABETIC RATS
Objective: The goal of the present examination was to investigate anti-diabetic activity of Azima tetracantha Lam. leaves in streptozotocin-induced diabetic rats. Materials and Method: At a regular interval of an experimental protocol, blood glucose, insulin, glycogen, HDL, LDL, VLDL, FFA, PL, and TC and organs to bodyweight proportion were assessed in streptozotocin-induced diabetic rats. Histolo...
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EXPLORATION OF AMORPHOPHALLUS PAEONIIFOLIUS STARCH AS NATURAL BINDER
The aim of the present work was to characterize the starchy components of Amorphophallus paeoniifolius tuber and evaluate its potential as a binder. The tuber starch was extracted and characterized in terms of Phyto-chemical and physicochemical properties. Cyproheptadine was selected as model drug, and drug excipient compatibility studies were carried. Granules containing 5%, 7.5%, 10%, and 12.5% ...
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STABILITY INDICATING UPLC METHOD FOR SIMULTANEOUS ESTIMATION OF DAUNORUBICIN AND CYTARABINE
The main objective of the study was to develop an RP-UPLC method for the simultaneous determination and validation of the Daunorubicin and Cytarabine in the pharmaceutical dosage form. The technique was developed by using the Mobile phase containing Buffer 0.01N KH2PO4: Acetonitrile used in the ratio 50:50 v/v and X-Bridge C18 (2.1 × 100 mm, 1.6 µm) as a stationary phase at a flow rate of 0.3 ml...
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PHYLOGENETIC CHARACTERIZATION OF POTENTIAL BIOACTIVE METABOLITES PRODUCING ACTINOMYCETES FROM MANGROVE SEDIMENTS
An attempt has been made in the present study to isolate and identify actinomycetes, which can produce bioactive metabolites possessing antimicrobial activity. The soil samples were collected from mangrove sediments of Krishna district, Andhra Pradesh. The potent secondary metabolite producing strains were isolated and designated as VLK-15, VLK-24, and VLK-56. Identification of the strains was car...
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APPLICATION OF BIOANALYTICAL METHOD IN PHARMACOKINETIC STUDIES OF DIKAMALI GUM BASED MICROSPHERES OF FLURBIPROFEN FROM RABBIT BLOOD SAMPLES
Preparation and evaluation of dikamali gum-based microspheres of Flurbiprofen, needed a suitable bioanalytical method. In this direction, we report the development of a simple RP-HPLC method for the determination of Flurbiprofen in rabbit plasma samples by using the standard internal method. The method was carried out on RP C18 column, with a mixture of the buffer: acetonitrile (60:40) as the mobi...
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