Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
SENSITIVE SPECTROPHOTOMETRIC METHOD FOR DETERMINATION OF VITAMINS (C AND E)
A sensitive, simple, accurate and fast method for vitamin C and E determination in pure and drug formulations using spectrophotometric was developed. The developed method is based on the formation of the charge transfer complex via the reaction between vitamins and Fe+3 [FeNH4(SO4)2.12H2O] in the presence of K3Fe(CN)6 which lead the formation of a blue-greenish colored product that has a maximum a...
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DESIGN AND FORMULATING GLICLAZIDE SOLID DISPERSION IMMEDIATE RELEASE LAYER AND METFORMIN SUSTAINED RELEASE LAYER IN BILAYER TABLET FOR THE EFFECTIVE POSTPRANDIAL MANAGEMENT OF DIABETES MELLITUS
In order to effectively manage the diabetic mellitus type-II hyperglycemic surge, bilayered tablets comprising of gliclazide in immediate release layer (IRL) and metformin in sustained release layer (SRL) have been designed and fabricated for years. Gliclazide suffers from reduced aqueous solubility of 0.19 mg/mL which remained a crucial problem for the biological effect as a result of reduced dis...
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1840
IN-VITRO EVALUATION OF THE ANTIOXIDANT POTENTIAL, TOTAL PHENOLIC AND FLAVONOID CONTENTS AND ANTIBACTERIAL ACTIVITY OF LAMIUM ALBUM EXTRACTS
Lamium album is used as a blood purifier, in the treatment of the respiratory tract diseases, diarrhea and bleeding. In this study antioxidants and anti-bacterial activities of its aerial parts and roots were investigated. Extracts were prepared by Soxhlet apparatus. Methanol used as extracting solvent. Phenol and flavonoids contents and antioxidant properties were evaluated by different methods. ...
3667
1523
IN-VITRO HYPOGLYCEMIC EFFECT OF FOENICULUM VULGARE MILL. SEEDS ON THE CARBOHYDRATE HYDROLYZING ENZYMES, α-AMYLASE AND α-GLUCOSIDASE
Diabetes is a metabolic disorder characterized by absolute or relative deficiency of insulin. Today, globally many therapeutic approaches are being innovated to decrease the postprandial glucose levels and adsorption through the inhibition of enzymes, α- amylase and α- glucosidase. Presently, these two enzymes offer for the maintenance of glucose levels in diabetic patients by hydrolyzing the ca...
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1618
ELECTROSPUN NANOFIBERS AS ADVANCED ANTIBACTERIAL PLATFORMS: A REVIEW OF RECENT STUDIES
This study aimed to introduce antibacterial nanofibers, produced by electrospinning as a novel technique in constructing nanostructured materials. In the electrospinning technique, a high voltage is applied to a polymer solution to overcome the surface tension. A charged polymer jet is ejected to a grounded electrode. As the solvent is evaporated, the electrospun fiber with diameter from micromete...
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2412
STUDY ON THE ANTI METASTATIC AND ANTICANCER ACTIVITY OF TRITERPENE COMPOUND LUPEOL IN HUMAN LUNG CANCER
Lup-20(29)-en-3-ol, known as Lupeol is one of the most extensively studied triterpene compounds for their diverse biological properties. Natural triterpenoids gain pre-eminence in cancer research owing to their effects in regulating transcription factors and pathways associated with cell proliferation. The objective of the present study was to evaluate the anticancer activity of Lupeol on human ad...
6274
1667
DEVELOPMENT AND VALIDATION OF NOVEL UV AND RP-HPLC METHODS FOR DETERMINATION OF CILNIDIPINE (A NEW GENERATION Ca CHANNEL BLOCKER) IN PHARMACEUTICAL DOSAGE FORM
An accurate and precise High-Performance Reversed-Phase Liquid Chromatographic and UV spectrophotometric methods were developed and validated for the quantitative determination of Cilnidipine, a novel generation Ca channel blocker in the pharmaceutical dosage form. Good quality chromatographic separation of Cilnidipine was carried out by using thermo scientific model C18 Column (4.6 mm i.d. × 250...
5328
2010
IN-VITRO ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF PITURANTHOS CHLORANTHUS AND ARTEMISIA VULGARIS FROM TUNISIA
Pituranthos chloranthus and Artemisia vulgaris L. are two of the most important aromatic and medicinal species from the Apiaceae and Asteraceae families, respectively. They are traditionally used in certain pathologies in which inflammatory processes are involved. The present study investigates the potential of aqueous extracts of Tunisian P. chloranthus and A. vulgaris as a natural alternative so...
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ACUTE AND SUB ACUTE TOXICITY STUDIES WITH GINGER EXTRACT IN RATS
The dry ginger rhizome was extracted with ethyl acetate, and gingerol content was enriched by liquid-liquid extraction. The extract was analyzed for the percentage of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol by HPLC. The acute toxicity was evaluated as per OECD guidelines 423. Ginger extract was fed at 2000 mg/kg body weight to overnight fasted female rats (8-10 weeks old; 160-180 g). Th...
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SALIVA-THE KEY REGULATOR OF ORAL CHANGES IN DIABETES PATIENTS
Saliva plays the most important role in the maintenance and preservation of the health of our oral cavity. In diabetes mellitus functions of salivary glands are impaired and as a consequence xerostomia develops. Hoposalivation leads to various oral mucosa alterations, ulcerations, taste alterations, burning mouth, dental decay, halitosis and various infections. All these alterations can compromise...
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