Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
NEW SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF TOLTERODINE IN BULK AND PHARMACEUTICAL FORMULATION
Simple, fast and economic spectrophotometric methods were developed for determination of Tolterodine in bulk and pharmaceutical dosage forms using water as the solvent. The quantitative determination of the drug was carried out using the zero order derivative measured at 281.5 nm, first order derivative measured at 274 nm and area under curve was measured in wavelength range of 276-286 nm. Calibra...
2967
1080
IN VITRO ANTIOXIDANT AND FREE RADICAL SCAVENGING POTENTIAL OF HOLOSTEMMA ADA – KODIEN K. SCHUM., AN IMPORTANT RARE MEDICINAL PLANT
The present study was undertaken to evaluate the in vitro antioxidant activities of hexane, ethyl acetate and methanolic extracts of Holostemma ada kodien root tubers. The above extracts exhibited a dose dependent scavenging activity against DPPH radicals, Superoxide radicals, and Nitric oxide radicals. Further, the MeOH, EtOAC extracts showed relatively higher reducing power compare to that of BH...
3075
961
ANTI-ULCER PROPERTIES OF ALKALOIDS ISOLATED FROM THE FRUIT PULP OF CUCUMIS METULIFEROUS (CURCURBITACEAE)
Anti-ulcer properties of the alkaloids isolated from the fruit of Cucumis metuliferous was investigated in mice. Ethanol-induced gastric lesion was used to assess the anti-ulcer activity. In this study, there was a significant (p<0.05) decrease in haemorrhages and ulcerations of the gastric mucosa at 500 and 1000 mg/kg of the alkaloid compared with control. The activity of the extract is compar...
3077
1022
SOLID LIPID NANOPARTICLES FOR ENHANCEMENT OF ORAL BIOAVILABILITY OF CEFPODOXIME PROXETIL
Solid lipid nanoparticles (SLNs) have been proposed as suitable colloidal carriers for delivery of drugs with poor bioavailability. The objective of this study was to develop and evaluate solid lipid nanoparticles of Cefpodoxime Proxetil (CP) for enhancement of bioavailability via its lymphatic absorption. Solvent evaporation technique was adopted to prepare Cefpodoxime Proxetil loaded SLN with Pr...
3337
1349
IN-VITRO ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL STUDIES OF BOERHAAVIA DIFFUSA LINN. ROOTS.
The present study was carried out to evaluate the antioxidant activity and phytochemical constituents of Boerhaavia diffusa Linn. (Nyctaginaceae) dried roots. The root extracts were prepared with chloroform, ethanol and water and screened for in vitro antioxidant activities by using assay of DPPH radical scavenging, antiproteolytic activity, polyphenol oxidase inhibition, hydroperoxide inhibition ...
4292
1539
EVALUATION OF ANTI-NOCICEPTIVE ACTIVITY AND BRINE SHRIMP LETHALITY BIOASSAY OF ROOTS OF LEEA MACROPHYLLA ROXB.
The ethanolic extracts and its different partitioning fractions of roots of Leea macrophylla (Leeaceae) were evaluated for their analgesic and preliminary cytotoxic activities. The analgesic activity was evaluated using the acetic acid-induced writhing test in mice while the screening of cytotoxic activity was done using brine shrimp lethality bioassay. In acetic- acid induced writhing test, the e...
3307
1151
EFFICACY OF AGERATUM CONYZOIDES AGAINST THE CONTROL OF MOSQUITOES
Mosquitoes transmit serious human diseases causing millions of deaths every year. Phytochemistry has proven that there are potential mosquito control agents and also alternatives to synthetic insecticides. The present paper reports Ageratum conyzoides commonly known as Kubhi in Hindi of family Astereacae. The plant after proper identification was collected shade dried and powdered to the fine mesh...
3467
1135
ZINC OXIDE NANOPARTICLES INDUCED HAEMOLYTIC CYTOTOXICITY IN HORSE RED BLOOD CELLS
Metal oxide in the nanorange acquires distinctive properties that depend on size, chemical composition and surface chemistry. Among the metal oxide nanoparticles, the zinc oxide nanoparticles (ZnO NPs) are commonly used for their antimicrobial properties. ZnO nanomaterials are incorporated into a variety of skin coatings because of their antimicrobial and/or antifungal properties. Most of the futu...
4020
1223
DEVELOPMENT AND OPTIMIZATION OF ITOPRIDE HYDROCHLORIDE FAST DISINTEGRATING TABLETS USING FACTORIAL DESIGN AND RESPONSE SURFACE METHODOLOGY
The objective of this work was to use a full factorial design and response surface methodology to optimize and prepare fast disintegrating tablets of Itopride hydrochloride (ITOHCl). Tablets were prepared by direct compression technique and evaluated for their drug content, weight variation, hardness, friability, wetting, disintegration time, and in-vitro release. In addition, the optimum formulat...
3722
1249
ASSESSMENT OF TRADITIONAL HOME REMEDY USAGE AMONG PEOPLE IN HARAR, ETHIOPIA
Many countries in Africa, Asia and Latin America use traditional medicine (TM) to meet some of their primary health care needs. In Ethiopia, Traditional Medicine (TM) is a part of the national heritage. Also Ethiopia is the home of many nationalities and remarkably diverse flora, including numerous endemic species that are utilized in the different traditional medical practices. Beyond the conveni...
19124
1400