Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
DEVELOPMENT AND IN VITRO EVALUATION OF SUSTAINED RELEASE FLOATING MATRIX TABLETS OF METFORMIN HYDROCHLORIDE
Floating matrix tablets of metformin hydrochloride were developed and evaluated for increase bioavailability by increasing gastric residence time and sustained release of drug on the upper part of gastrointestinal tract thereby diminishing side effects and enhanced patient compliance. Metformin hydrochloride, an oral antidiabetic having narrow absorption window in the upper part of gastrointestina...
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1639
IN-VITRO ANTIOXIDANT ACTIVITY OF THE SUCCESSIVE EXTRACTS OF RICINUS COMMUNIS STEMS
There is increasing evidence to support the involvement of free radical reactions in several human diseases. n recent years, it has become increasingly apparent that in man, free radicals play a role in a variety of normal regulatory systems, the de-regulation of which may play an important role in inflammation. Active oxygen species and other free radicals have long been known to be mutagenic. Fu...
4887
1589
ANTI ULCER ACTIVITY OF AQUEOUS EXTRACT OF ANNONA SQUAMOSA LEAVES ON RATS
The anti-ulcer activity of aqueous extract of Annona squamosa leaves was investigated on a indomethacin induced ulcer models in wistar rats. In model the common parameter determined was ulcer-index. aqueous extract of dosage 175, 350 mg/kg p.o produced significant inhibition of gastric lesions induced by indomethacin induced ulcers. The extract 175mg/kg & 350mg/kg showed significant (p<0.01...
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1666
COMPARATIVE STUDIES ON SKIN PERMEATION OF MICONAZOLE USING DIFFERENT NOVEL CARRIERS
Purpose: Miconazole nitrate is a widely used antifungal agent but its use in topical formulation is not efficacious because deep ereated fungal infections are difficult to treat with conventional topical formulation. The purpose of this study was to prepare miconazole incorporated different novel carriers such as liposomes, ethosomes and to compare their in vitro skin permeation studies with plane...
4894
1976
PHYTOCHEMICAL AND PHARMACOLOGICAL SCREENING OF SPHAERANTHUS INDICUS LINN. FOR ANTIMICROBIAL ACTIVITY
Sphaeranthus indicus Linn (Asteraceae) is a common annual spreading herb found in rice field throughout India. Six crude extracts were prepared from the whole plant Sphaeranthus indicus using different solvents by cold maceration process. The extracts were subjected to screening to detect potential antimicrobial activity against S. aureus, B. substillus, P. Gentamycin and Nystatin as standard by c...
5028
2397
RP- HPLC METHOD DEVELOPMENT AND VALIDATION OF CANDESARTAN CILEXETIL IN BULK AND THEIR PHARMACEUTICAL DOSAGE FORMS
This paper describes the analytical method suitable for validation of Candesartan Cilexetil (CDN) by reversed Phase liquid chromatography (RP-LC) method. The method utilized RP-LC (Shimadzu LC-10AT with UV detector) model and Hypersil ODS C-18 (250 x 4.6 mm, packed with 5 micron) column was used for the separation. The mobile phase was consists of acetonitrile:0.05 M KH2PO4 buffer in the ratio of ...
6650
2223
ANTIBACTERIAL ACTIVITY OF RICINUS COMMUNIS LEAF EXTRACT
Based on the scope given by traditional knowledge, present study was conducted. The aim of the present study was to evaluate the antibacterial activity of castor (Ricinus communis, Family: Euphorbiaceae) leaf extract using five bacteria; two Gram-positive bacteria (Bacillus subtilis and Staphylococcus aureus) and three Gram-negative bacteria (Escherichia coli, Proteus vulgaris, Pseudomonas aerug...
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2712
EVALUATION OF ANXIOLYTIC ACTIVITY OF HYDROALCOHOLIC ACTIVITY OF TEPHROSIA PURPURIA (L) PERS ON SWISS ALBINO MICE
The present work is to evaluate the anxiolytic activity of a hydroalcoholic extract of Tephrosia purpuria (L) Pers (HAETP) in mice using the elevated plus-maze (EPM), elevated zero-maze (EZM), Y-maze and hole-board models. Furthermore, the anxiolytic effects of HAETP were compared to a known active anxiolytic drug diazepam. The extract, administered orally, in two different doses of HAETP 200 mg/k...
4649
1900
TRANSDERMAL DRUG DELIVERY SYSTEM (TDDS): AN OVERVIEW
The transdermal route of drug delivery has attracted researchers due to many biomedical advantages associated with it. However, excellent impervious nature of skin is the greatest challenge that has to be overcome for successfully delivering drug molecules to the systemic circulation by this route. This review describes enhancement techniques based on drug/vehicle optimization such as physical and...
9593
2350
QUALITATIVE AND QUANTITATIVE ESTIMATION OF GALLIC ACID AND ASCORBIC ACID IN POLYHERBAL TABLETS
An HPTLC method was developed for Qualitative and Quantitative Estimation of Gallic Acid and Ascorbic Acid in Polyherbal Tablets (Amalant and Sookshma Triphala Tablet) containing Embelica Officinalis, using precoated HPTLC silica gel 60 F254 as Stationary Phase and Mobile Phase for Gallic Acid is Toluene: Ethyl Acetate: Formic Acid (6:3:1v/v/v) and for Ascorbic Acid is Ethyl Acetate: Acetic Acid G...
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