Posted by admin on Dec 25, 2014 in |
Phyllanthus amarus Schum. and Thonn. is one of the highly used medicinal plants both traditionally and scientifically. Phytochemical screening is of high importance to establish the claims of medicinal uses by traditional and folk medicine practitioners. Since, environmental, climatic and soil conditions have strong effect on production and level of particular phytochemicals in a given plant part, present study was focused on the locally available plant variety and to establish the traditional claims for its medicinal uses. The qualitative and quantitative estimation of different plant parts of P. amarus collected from Jabalpur, India revealed the presence of high amounts of phenolic compounds, alkaloids, saponins, flavonoids and terpenoids in aerial parts of the plant i.e. stem and leaf. Roots and fruits showed high amount of phenolics and terpenoids. This is the first study that was performed with separated plant parts and not with the whole plant. The present study is an attempt to reinvestigate Phyllanthus amarus Schum and Thonn from Central India for the phytochemical analysis and correlate the traditional...
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Posted by admin on Dec 25, 2014 in |
The Telecobalt machines are extensively used in developing countries due to its lesser cost, lesser power consumption and easy maintenance. The high activity source can be extensively used for at least 6-8 years due to its long half-life. Installing a Telecobalt unit comprises of fixing the machine in the treatment room, ensuring its mechanical motions, source loading and all other related Quality Assurance Checks. The Bhabhatron-II, an indigenous Telecobalt machine is installed at Acharya Tulsi Regional Cancer Centre, produced in India by Department of Atomic Energy, Mumbai. This paper describes about the installation & Commissioning of Bhabhatron-II and their related Quality Checks. The necessary Radiation Quality Assurance checks such as Combined Jaw Transmission, Individual Jaw Transmission, and ON Position Leakage in patient plane, Leakage in other than patient plane are measured. The collimator transmission of combined jaw and, Individual jaws (X & Y) are measured and they are 0.024%, 0.347% & 0.635% of the useful beam respectively. The ON position leakage in patient plane is measured by forming an...
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Posted by admin on Dec 25, 2014 in |
The main objective of the study was to assess the prevalence of polycystic ovary syndrome at a tertiary care hospital. This study was a prospective observational study performed for a period of 6 months in infertility and gynecology clinic. For making a positive diagnosis of PCOS, all subjects were interviewed to furnish details of menstrual history including regularity, duration of cycles, and number of cycles per year or intermenstrual interval. Transabdominal ultrasonography and tests like Tests like fasting blood glucose, fasting insulin, follicle stimulating hormone (FSH), luteinizing hormone (LH), LH:FSH ratio and serum testosterone were performed. A total two hundred eight patients were attended infertility and gynecology clinic during the study period of six months, of which 67 (32%) patients were meeting the study criteria were included and assessed for the presence of polycystic ovary syndrome. Of the 67 patients, 57 patients experienced oligomenorrhea and remaining 10 patients had amenorrhea. 32 patients had hirsutism, 18 patients had acne and 4 patients had alopecia.Transabdominal ultrasonography showed the presence of polycystic...
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Posted by admin on Dec 25, 2014 in |
Superparamagnetic iron oxide nanoparticles have been used for various industrial and clinical applications. In the present study, biosynthesis of superparamagnetic Fe3O4 nanoparticles was carried out using a fungal isolate. The fungal isolate was identified as Fusarium oxysporum SK through 18S ribosomal DNA sequence analysis. The synthesized magnetic nanoparticles were subjected to Transmission Electron Microscopy (TEM) and Scanning Electron microscopy (SEM) to measure the morphology and size of the nano particles. The topology was assessed by X-ray Diffraction (XRD) analysis and the magnetic property was assessed by Vibrating sample magnetometry (VSM). The nanoparticles were spherical in shape and the average size was measured as 15nm. The VSM data showed that the nanoparticles were superparamagnetic and the saturation magnetization was found to be 19.9emu/g. Since the particles were synthesized for the application in biomedical field, the particles were tested for toxicity against human monocytes through MTT [3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide] assay. The MTT assay results confirmed the particles are...
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Posted by admin on Dec 25, 2014 in |
The biological synthesis of magnetite nano-bio hybrid using plant extracts plays an important role in the field of nanotechnology. The present study demonstrates bio-reductive synthesis of protein coated magnetite (Fe3O4) nano-bio hybrid using leaf extracts of Datura inoxia plants and its encapsulation into liposome. Liposome is vesicles of varying size consisting of a spherical lipid bilayer and an aqueous inner compartment that are generated in vitro. Magnet-driven liposome used for the targeted delivery of drugs to organs and tissues. These liposome preparations contain encapsulated drug components and finely dispersed magnetic particles inside the liposome. Liposome is useful in terms of biocompatibility, biodegradability, low toxicity and can control bio distribution by changing the size, lipid composition, and physical characteristics. Furthermore, liposome can entrap both hydrophobic and hydrophilic drugs and are able to continuously release the entrapped substrate, thus being useful drug carriers. The nano bio hybrid based magneto liposome has been prepared by reversed phase evaporation (REV) method using oleic and linoleic acid which has been shown to be driven...
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