Posted by admin on Feb 28, 2023 in |
The herbal-based formulation “Sugar Care” a product of Miracle Drinks was assessed for an anti-diabetic property on 12 diabetic patients. Each patient was prescribed 15ml of Sugar Care (S10) morning and evening after meal and 15ml of cardiovascular care (S3) in the afternoon. Morning and night doses of sugar care were given along with 15ml of Liver Care (S4) and Renal Care (S5). After 30 days of treatment, the biochemical markers related to blood sugar, like fasting blood sugar (FBS), post-prandial blood sugar (PPBS), and haemoglobin-linked sugar or HBA1C were assessed. A significant reduction of FBS i.e., 50 to 72.2%, was observed in 5/12 diabetic patients. Female patients showed a better recovery rate than male patients, who were 3/4, and 3/8 patients, who showed more than 50% reduction in FBS. A similar recovery trend was also noticed in both male and female diabetic patients that showed a substantial decline in PPBS after treatment with Sugar Care. Three female patients showed substantial change from 346.0±6.0, 420.0±3.0 and 407.3±1.53mg/dl to 158.0±2.0,...
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Posted by admin on Feb 28, 2023 in |
The process of eliminating viral infection and massive control from spreading furthermore by any variants may lead to a pandemic in the near future. On the other aspect, the impact of eradicating by the initial stage to prevent, treat carcinoma to decline the affected and death rate to maximum amount by Molecular Docking. The quickest and easiest method to search out the potential drugs is by analyzing the ligand-protein interactions compared to the traditional ways. Drugs of antivirals and anti-cancer drugs are given for treating viral infections and cancers. Massive kinds of viruses affect humans with several diseases, from self-curable diseases to acute mortal diseases. In cancer, the diseases are known by the cells within humans; multiplication occurs and forming the tumors of malignant cells with the flexibility to be a pathological process. Herbal medicines are known to play enormous role by giving initial priority. Various plant species are being employed to cure or prevent viral infections and cancers. Molecular docking provides a fast understanding of the ligand’s exploration...
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Posted by admin on Feb 28, 2023 in |
Medicinal plants are an abundant source of bioactive compounds, which have been used for thousands of years against different diseases because plants have antibacterial, anti-inflammatory, and antifungal activities. All of the medicinal plants that may be found on earth today have specific therapeutic use and importance. Our research work is based on the qualitative phytochemical studies of extract obtained from leaves of Tinospora cardifolia, Punica granatum, Moringa oleifera, Momordica charantia, Annona squamosa, Eugenia jambolana, and Carica papaya were collected from Bhadravathi taluk of Shivamogga district. These leaf extracts were prepared using various solvents like methanol, acetone, chloroform, and aqueous. Phytochemical screening of these medicinal plants showed the maximum amount of alkaloid, flavonoid, phenol, terpenoid, and tannin in all the extracts. However, methanolic extracts showed good results when compared to other solvent systems. The phytochemical screening of these medicinal plants is commercially very significant and is very important for producing new medication for the treatment of different...
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Posted by admin on Feb 28, 2023 in |
Aluminium neurotoxicity is implicated in Alzheimer’s disease, this multifactorial disorder, with neurodegeneration and dementia as hallmarks. Aluminium toxicity is due to imbalances between free radicals and antioxidants formation, leading to oxidative stress. However, protection against aluminium toxicity is yet to be fully realized. Therefore, this study investigated Zingiber officinale (ZO) neuroprotective potential against aluminium chloride (AlCl3)-induced neurotoxicity in Swiss mice. Forty-eight animals were divided into eight groups (n=5) with treatment lasting three weeks: Group 1 (control) received 1 ml/kg of distilled water, while groups 2-8 respectively, received AlCl3 (100 mg/kg), donepezil (2.5 mg/kg), ZO ethanol extract (474 mg/kg, 949 mg/kg and 1,423 mg/kg), ZO dichloromethane extract (949 mg/kg), and ZO n-hexane extract (949 mg/kg). Morris water maze test was performed, and the mice were sacrificed. Brain homogenates were assayed for catalase (CAT) and glutathione peroxidase (GPx) levels. AlCl3 treatment led to significantly (p<0.05) high escape latency and less latency in the hidden platform quadrant and reduced brain CAT and GPx levels compared with the control. The groups treated with...
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Posted by admin on Feb 28, 2023 in |
Background: Previous hospitalization, nosocomial infection and specific risk factors like prolonged quinolone use for Spontaneous Bacterial Peritonitis prophylaxis can be related to drug-resistant bacterial infections and high mortality in liver cirrhosis. Aim and Objectives: To study the prescription pattern of antibiotics used in SBP, compare the efficacy and emerging resistance of antibiotics, and classify patients with different types of ascites. Methodology: The study was conducted in liver cirrhosis patients with SBP retrospectively (2 years) and prospectively (6 months) by a convenient sampling technique. The study was carried out in NIMS Medicity, Thiruvananthapuram. Relevant data were collected via pre-approved data collection form and were subjected to SPSS statistics 22 and R software 4.1.1. analysis. Results: In our study, a total of 116 patients in the retrospective and 21 patients in the prospective study were obtained. 26 patients (22.4%) from the retrospective study and 4 patients (19%) among the prospective study had culture-positive ascitic fluid culture. E. coli was the most commonly obtained organism (69.24%). Third-generation cephalosporins showed higher resistance in...
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