Posted by admin on Nov 30, 2022 in |
Background: Golfer’s elbow, commonly known as medial epicondylitis, is an overuse syndrome caused by an eccentric overload of flexor-pronator mass on the medial epicondyle. This is produced by repetitive actions causing micro-trauma to insert the flexor-pronator mass, which affects the pronator teres more than the flexor carpi radialis. This study evaluates the efficacy of platelet-rich plasma and steroid injections in treating the golfer’s elbow. Materials and Methods: This is a prospective study including 30 patients. They were divided into 2 groups Group A (n = 15) and B (n = 15). PRP injection was given for Group A patients, and for Group B patients, Steroid injection was given. There was a total of 17 Females and 13 males in the study. All the patients were followed up at 1st, 2nd and 6th months post-procedure, VAS and DASH scores were analyzed. Results: In group A, the mean VAS score pre-PRP was 6.8, which improved to 1.93,1.26 and 1.06, and the mean DASH score pre-PRP injection was 34.8, which improved to...
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Posted by admin on Nov 30, 2022 in |
The nutritional quality of soil plays a key role in the growth of plants as soil minerals act as a source and sink for providing the essential nutrients to plants. The fertility of the soil and nutritional management are the two important factors that directly influence plants’ productivity and quality. Soil management is an important tool for agriculture to provide nutritious food. Soil management is essential for maintaining the quality of soil and soil life support system. Soil quality includes soil structure, fertility, conservation, and organic matter. The soil management practices are generally implemented to enhance the productivity of soil. Soil testing is the first step of managing the fertility of soil. The soil testing provides valuable information about the nutritional levels (micronutrients, macronutrients, organic carbon content (OC), electrical conductance (EC), pH etc.) of soil. This article shows the influence of the environment on the fertility and nutritional quality of soil that has been collected from different areas of Rajasthan. The soil test report is helpful in the recommendation...
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Posted by admin on Nov 30, 2022 in |
Background: Hypertension is the most common disorder affecting different age groups of people. The increased blood pressure creates discomfort in the patients; these cardiovascular diseases are risky which can lead to “mortality and morbidity”. Labetalol hydrochloride is an anti-hypertensive drug used to treat high blood pressure and Angina. These compounds possess less water solubility and low bioavailability (25%). Objective: The current study is aimed to develop Labetalol hydrochloride Liquisolid Tablets to enhance its solubility. Results: The in-vitro dissolution studies showed enhanced drug release at 98.43% with Avicel PH102 as carrier and 96.54% with Fujicalin as the carrier. Hence F3 with 98.43% drug release was considered the optimized formulation. The optimized formulation batch F3 was subjected to stability studies as per the ICH guidelines. There was no significant change observed. Conclusion: It can be concluded that labetalol hydrochloride was successfully incorporated as a liquisolid tablet by the direct compression method. The direct compression method employed was easy and can be widely used’. The powder blend of F3 containing avicel pH...
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Posted by admin on Nov 30, 2022 in |
Plants have been utilized as medicine since the ancient period, and they are at the basis of much of modern medicine. Plants provide the basis for many conventional medications and the majority of the few successful drugs. Herbal formulations are becoming increasingly popular nowadays. But in some cases, side effects of the herbal formulations have been reported. So, according to the AYUSH ministry, herbal formulations should also be evaluated for toxicity to determine their safe dose. This study aims to critically assess the scientific evidence for herbal formulations’ acute and subchronic toxicity. Six herbal formulations of Shree Dhanwantri Herbals were tested for toxicity in rats. An acute and subchronic toxicity study was conducted on Wistar rats following OECD-423 and OECD-408 guidelines, respectively. No mortality or abnormal behavior was observed in the acute toxicity studies. In the sub-chronic toxicity study, testing formulations did not produce any significant changes in rats’ behavior compared to the control group. Further, hematological and biochemical parameters were also found normal. Histopathological analysis revealed that treated...
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Posted by admin on Nov 30, 2022 in |
A metabolic disease called diabetes mellitus in which blood glucose levels are abnormally high. It could be due to tissue glucose intolerance and impaired insulin production. In a Type II diabetes model generated by Streptozotocin and nicotinamide, the antidiabetic potential of ethanolic and aqueous leaf extracts of Michelia champaca (Magnoliaceae) was compared to a control group of diabetes. The anti-diabetic activity was tested on Wistar rats. The effective antihyperglycemic ethanolic and aqueous leaf extracts were tested at two doses of 250 mgkg-1 b.w. and 500 mgkg-1 b.w. for 21 days. Compared to the diabetic control group, the ethanolic extract at a dose of 500 mgkg-1 b.w. exhibits a highly significant (p<0.001) reduction in fasting blood glucose levels. After the trial, the blood sample was drawn from all animals for biochemical analysis. In extract-treated diabetic rats, the serum lipid profile was calculated. The biochemical investigation, serum cholesterol, serum triglyceride, high-density lipoprotein, and low-density lipoprotein support the ethanolic extract’s anti-diabetic...
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