Posted by admin on Dec 31, 2024 in |
The co-occurrence of Type 2 Diabetes Mellitus (T2DM) and hypertension is a growing public health concern in India. Effective management requires careful consideration of prescribing indicators, pharmacoeconomic implications, and therapeutic adherence. This review aims to explore the current landscape of prescribing practices, economic burden, and adherence patterns among Indian patients suffering from both T2DM and hypertension. A thorough understanding of these factors can guide policymakers, healthcare professionals, and researchers toward more efficient and cost-effective treatment...
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Posted by admin on Dec 31, 2024 in |
Medicinal plants are presently viewed as being of great value because of their unique qualities as a significant source of medicinal phytochemicals that might result in the creation of new medications. Oldenlandia pumila (L.f.) DC. belong to Rubiaceae family and found as a weed throughout India. Oldenlandia pumila (L.f.) DC. has antibacterial, antiviral, antioxidant, anticancer, anti-inflammatory, and antiplasmodial activities. The effects of three different solvents were investigated in the current study to determine the presence of phytochemicals, total phenolic content, total flavonoid content, and antioxidant assay. The preliminary phytochemical analysis revealed the presence of carbohydrates, flavonoids, tannins, and alkaloids whereas finding the absence of proteins and glycosides in the various extracts. Phytochemical analysis showed that Oldenlandia pumila (L.f.) DC. contained TPC ranging from (82.235 ± 0.005 mg to 424 ± 0.005 mg GAE /g) while TFC ranging from (38 ± 0.006 mg to 336 ± 0.006 mg GAE /g). The TAC ranges from (18.285 ± 0.007 to 89 ± 0.006 mg AE/g) and the TAC ranging from (64.8 ±...
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Posted by admin on Dec 31, 2024 in |
Background: Human Papilloma Virus (HPV) is a common sexually transmitted infection, and its persistence can lead to cervical cancer. It can be prevented by vaccines. Objectives: The study was conducted with the objective of analyzing knowledge, attitude, and practice towards HPV infection and the acceptability of vaccination among medical students. Methodology: Around 405 students in a tertiary care centre were randomly selected. Data were collected using a validated questionnaire and statistically analyzed using MS Excel and SPSS version 16. Results: Clinical students had significantly (p<0.01) better knowledge than non-clinical students in areas like HPV and cervical cancer (99%, 91%), sexual transmission (98%, 86%), and HPV vaccine (92%, 74%). Non-clinical students significantly (p<0.01) differ from clinical students by agreeing in areas related to vaccination, perceived as “sexually active” (32%, 22%), parent’s decision (40%, 25%) and partner’s opinion (81%, 56%). None of the students were ever screened for HPV infection or cervical cancer. No difference was seen between the phases related to HPV transmission through direct contact and non-curability. Conclusions: Clinical...
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Posted by admin on Dec 31, 2023 in |
Alzheimer’s disease (AD) is one of the most well-studied neurodegenerative conditions. It is a debilitating chronic disease of the central nervous system (CNS). Almost 131.5 million individuals are predicted to be affected by the disease by 2050. The main effects of AD are cognitive decline and language problems. One of the factors contributing to AD is the gradual decrease in the brain’s concentrations of the neurotransmitter acetylcholine. The breakdown of acetylcholine is carried out by the increased activity of the acetylcholinesterase (AChE) enzyme within the brain. Many natural and synthetic acetylcholinesterase inhibitors (AChEIs) have been created in order to slow down the progression of the disease over the years. Currently, there are two potential AChEIs (Donepezil and Galantamine) that have shown positive clinical advantages. Furthermore, Rivastigmine is claimed to be an anti-AChE molecule showing the effects similar to Donepezil and Galantamine. The knowledge of specific as well as multitargeted molecules to treat or cure AD is the ultimate route to reach achievements in the field of AD medication. The intention...
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Posted by admin on Dec 31, 2023 in |
Video games can be symbolized as an escapism from the anxiety and pressure during the COVID-19 pandemic where social distancing is inevitable. Their growing popularity over the past decade has built the questions on how they might affect the physical health of the population. Our study aimed to determine the physical activity level with the frequency of exposure to video gaming among the pharmacy students during the pandemic. The cross-sectional study was conducted using an online survey consisting of a set of validated questionnaires modified from published literatures and the International Physical Activity Questionnaire (iPAQ) among the students at the Faculty of Pharmacy, Universiti Teknologi MARA. The survey was distributed to the students via e-mail and social network from April until June 2020 amid the Movement Control Order. A total of 314 sample were collected and majority of the respondents were females (55.1%) and Malay (96.5%). Our results showed that most students spent an average of 1 to 3 days per week playing video games (48.1%), with the frequency...
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