Posted by admin on Jul 31, 2023 in |
Objective: This work aims to evaluate in in-vivo the Antiarthritic and Anti-inflammatory activities and in-vitro antioxidant activity on Poly Herbal Formulation in rats. Method: Arthritis is a disorder of change in joint architecture and ligament degeneration. In this polyherbal formulation, medicinal plants were Zingiber officinale (33.931mg), Piper nigrum (33.931), Piper longum (33.931mg), Spergularia daemia (30 mg), Delonix elates (30 mg), Acalypha indica (30 mg), and Carum copticum (101.79 mg), which are well-known plants throughout India. They are commonly used to treat various disorders like cancer, diabetes, arthritis, rheumatoid arthritis, atherosclerosis, and chronic inflammatory disorders. The quality of finished products was evaluated as per the World Health Organization’s guidelines for the quality control of herbal materials. Arthritis and inflammation were induced in both male and female Sprague-Dawley rats. Freund’s complete adjuvant (FCA) is used for antiarthritic effect. Carrageenan-induced is used for the anti-inflammatory effect of polyherbal formulation (Rheumatigo) was studied at doses of 250 and 500 mg/kg and the effects were compared with prednisolone (10 mg/kg) and diclofenac (20 mg/kg)....
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Posted by admin on Jul 31, 2023 in |
Post-COVID syndrome is defined as COVID-19 associated illness that extends for more than three weeks from the onset of symptoms, and chronic COVID-19 is an illness that extends beyond 12 weeks from the onset of symptoms. An online survey was conducted where 400 Covid-19 infected, participated from various areas of India. Among 400, 58% (232) had complaints of persistence of Covid symptoms. The most common long-term clinical manifestations identified based on this study include fatigue, cough, shortness of breath, and myalgia. Patients who exhibit symptoms such as fatigue, cough, and shortness of breath early in their condition are more prone to developing post-COVID syndrome. The results show that long-term clinical manifestations after mild and moderate COVID-19 are common and lead to limitations of activities and participation. However, in most cases, they are not severe and do not lead to frequent or serious issues with quality of life or workability. Thus, early rehabilitation is needed during the acute phase of illness, including mobilization, psychological support, and respiratory...
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Posted by admin on Jul 31, 2023 in |
The study aims to estimate the cost expenditure in chronic kidney disease patients. A prospective, observational study was carried out in a tertiary care hospital in south India for around 6 months. In the 201 patients enrolled in the study, 137 were males and 64 were females, aged 18 years or older, diagnosed with 3-5 and 5D stages of chronic kidney disease included in the study. Patient data were collected from the patient medical records, and direct and indirect medical cost analyses were analyzed. Descriptive analysis was done for age, gender, stages, co-morbidities, socioeconomic status, food habits, family history and occupational status. The P value of <0.05, was considered significant. The current study reveals that the social cost, including both direct and indirect medical costs, increases in the advanced stages of CKD. Patients on HD had the highest economic burden compared to other stages...
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Posted by admin on Jul 31, 2023 in |
Respiratory system is one of the vital systems of the body which is affected negatively by air pollutants, viral and bacterial infections. These infections can lead to several chronic diseases. Modern medicines can help treat these diseases, but they have several side effects that can further lead to other health-related troubles. In India, many people still use herbal remedies to treat mild infections as first aid. Traditional healers or vaids still use these herbal medicines to treat severe respiratory problems such as asthma, tuberculosis, whooping cough, etc. This review aimed to gather information about medicinal plants used to treat various respiratory problems in different areas of India. Relevant data about various ethnobotanical studies conducted in various country states were extracted from published literature and analyzed. Two hundred thirty-nine plant species belonging to 193 genera and 80 families were. The maximum number of plant species belonged to the family Asteraceae. Solanum was the genus with the maximum number of species. All plant parts, including roots, stem, rhizome, leaves, flowers, fruits,...
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Posted by admin on Jul 31, 2023 in |
Introduction: Due to the appropriate use of antibacterials, management of infectious diseases has undergone a revolutionary change. However, inappropriate use leads to several problems, including increased antibacterial resistance, adverse drug reactions, infection severity, increased treatment cost, and health care burden. Antibacterials drug utilization studies are valuable in overcoming the inappropriate and promoting the appropriate use of antibacterials. Therefore, the current study aims to estimate the pattern of antibacterial drug utilization by using WHO prescribing indicators. Material & Methods: A Non-interventional, Cross-sectional study was conducted among 800 OPD patients of SHKM, GMC, Nuh, and Haryana over a period of 12 months. A simple random sampling technique was employed to select prescriptions during data collection. Data processing and analysis were done using SPSS version 20. Results: 2105 patients were screened, and 800 patients were included in the study based on inclusion criteria. It was found that the maximum number of patients were in the adult age group (43%), followed by 29.8% in the paediatric age group. There were 4.56 drugs prescribed...
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