Posted by admin on Sep 1, 2012 in |
Tinospora cordifolia is known for a wide range of medicinal properties. In this study, cardiovascular and antimicrobial properties of aqueous and ethanolic extracts of Tinospora cordifolia were evaluated. Dose dependent negative ionotropic and chronotropic effects were observed with both aqueous and ethanolic extracts. The effects were antagonized by atropine indicating involvement of muscarinic receptors. Maximum antimicrobial activity was found with ethanolic extract of Tinospora cordifolia (15mm) against Pseudomonas aeruginosa. The organism showed resistance to aqueous extract giving an inhibition zone of 0.3mm. The data suggest that Tinospora cordifolia could be of benefit in arrhythmias and microbial infections....
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Posted by admin on Sep 1, 2012 in |
Tridax procumbens L. is a well known medicinal plant. In the present study alkaloids from pedicle and buds of the plant were extracted and evaluated for antimicrobial activity by ‘Disc Diffusion Assay’ against selected bacteria (Escherichia coli, Staphylococcus aureus and Proteus mirabilis) and fungi (Aspergillus flavus, Aspergillus niger, Candida albicans and Trichophyton mentagrophytes). Minimum inhibitory concentration, minimum bactericidal/fungicidal concentration and total activity of each active extract were also evaluated. Significant antibacterial activity was recorded by alkaloids of pedicle against P. mirabilis (IZ 20mm, AI 0.83 and same MIC, MBC 0.039 mg/ml) and antifungal activity was recorded by buds against C. albicans (IZ 9.2mm, AI 0.92, MIC 0.625 mg/ml and MFC 1.25 mg/ml). MIC ranged from 0.039 mg/ml-0.625 mg/ml and MBC/MFC ranged from 0.039 mg/ml-1.25 mg/ml against susceptible pathogens. It is noteworthy that MIC values of active extracts was found very low (0.039 mg/ml-0.625 mg/ml) and was recorded below 1 mg/ml against inhibited pathogens, thus ascertain their strong antimicrobial potential against selected microbes. Thus, the result of the present study...
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Posted by admin on Sep 1, 2012 in |
Validation is an integral part of quality assurance; the product quality is derived from careful attention to a number of factors including selection of quality parts and materials, adequate product and manufacturing process design, control of the process variables, in-process and end-product testing. Recently validation has become one of the pharmaceutical industry’s most recognized and discussed subjects. It is a critical success factor in product approval and ongoing commercialization, facilities and processes involved in pharmaceutical manufacturing process impact significantly on the quality of the products. Process controls are mandatory in good manufacturing practice (GMP). The purpose is to monitor the on-line and off-line performance of the manufacturing process, and hence, validate...
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Posted by admin on Sep 1, 2012 in |
Pregnancy can be the most paranormal and exciting time for expectant mother. Nature provides us with many tools for supporting both the mother and baby through this time of growth and renewal, to strengthen the spirits and body to promote a healthy pregnancy and birthing process. Pregnant and lacting mother need to be educated on the need for caution when using herbs during pregnancy and lactation particularly in view of lack of complete information. The women self administer herbal medicines both before and after pregnancy often without any recognition of their potential hazards. The use of herbal supplements in pregnancy and lactation is likely to be relatively high and its importance ascertains what supplements women are taking. Pregnancy and lactation care providers should be aware of common herbal supplements used by women and of evidence regarding potential benefits or harm. Midwives and obstetricians have an obligation to facilitate women’s wishes without condemnation, but this must be tempered with accurate information to ensure that use of herbal remedies in pregnancy...
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Posted by admin on Sep 1, 2012 in |
Cassia nodosa Bunch.is an ornamental tree belonging to family Leguminosae, popularly known as Pink Shower is a perennial tree. Laboratory evaluations were made to asses the study of primary metabolites in different plant parts of Cassia nodosa Bunch. The highest amount of soluble sugars (10.27mg/ gdw), lipids (32.36mg/gdw), phenols (20.0mg/gdw), DNA (11.78mg/gdw) and Chlorophyll- a+b (0.94mg/gdw) was observed in pods, ascorbic acid (0.867 mg/gdw), proteins (115.0mg/gdw), RNA (4.60mg/gdw) and carotenoids (0.554mg/gdw) in leaves and starch (10.02mg/gdw) in stems. Similarly lowest amount of proteins (39.48mg/gdw), phenols (4.67mg /gdw), RNA (0.49mg/ gdw) and DNA (1.76mg/gdw) was observed in leaves, starch (3.76mg/gdw) in flowers, soluble sugars (2.45mg/gdw), lipids (3.48mg /gdw), ascorbic acid (0.089mg/gdw) in...
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