Posted by admin on Aug 31, 2025 in |
Breastfeeding mothers often experience milk leakage and discomfort, highlighting the need for innovative, sustainable and hygienic nursing pads. This study explores the potential of banana pseudostem fibre as a natural, eco-friendly material for nursing pads. The research involves the extraction, processing and characterization of banana pseudostem fibres, followed by the development of a novel nursing pad prototype. The water absorption and antibacterial properties of the banana pseudostem fibre were evaluated, showing a high-water absorption percentage (88.52%) and broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria. The results demonstrate the suitability of banana pseudostem fibre as a sustainable and hygienic material for nursing pads. The developed prototype offers improved comfort, support, and absorbency, minimizing the risk of bacterial growth and infection. This research contributes to the development of eco-friendly, sustainable, and hygienic nursing pads, addressing the needs of breastfeeding mothers while promoting environmental...
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Posted by admin on Aug 31, 2025 in |
The prevalence of psychiatric disorders in AUD, the association between the severity of AUD and psychiatric disease, the influence of treatment of AUD on relief of psychiatric symptoms and vice-versa has been studied in various parts of the world. In India, the influence of various socio-economic factors and the lifestyle of the individuals is different to other parts of the world. There is paucity of the literature regarding the association of AUD with psychiatric disease, influence of AUD on pharmacotherapy of psychiatric disorders, the quality of life of patients with co-existing AUD and psychiatric disorders. This review aims to study the association and co-occurrence of AUD and psychiatric disorders and influence of combined disorders on the...
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Posted by admin on Aug 31, 2025 in |
Millets are small-seeded grasses that have nutraceutical properties due to high content of proteins, dietary fibre, vitamins, antioxidants, and other valuable phytochemicals, important for health and wellbeing. The objective of the research was to analyse the phytochemical compounds and antioxidant properties of minor millet varieties viz., Kodo, Proso, Barnyard, Finger, Foxtail, and Little Millets. A quantitative phytochemical examination revealed the presence of phenols, steroids, alkaloids, saponins, flavonoids, and tannins irrespective of the extraction method used. Antioxidant assay was done by the phosphomolybdate method. These findings indicate that different millet types possess distinct phytochemical profiles. Finger Millets and Foxtail Millets were rich in phenols and flavonoids, while Barnyard Millets had increased levels of alkaloids, saponins, and tannins. The antioxidant evaluation of Kodo, Proso, Barnyard, Finger, Foxtail, and Little Millets extracts showed that the Finger millet exhibited the highest antioxidant activity (4.12 μg AAE/ml in DW and 5.34 μg AAE/ml in Me). Methanol extracts generally showed higher antioxidant values than distilled water extracts, indicating that methanol is a more effective solvent...
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Posted by admin on Aug 31, 2025 in |
Introduction: Hypertension is a leading global health concern, contributing significantly to cardiovascular morbidity and mortality. Despite the availability of various antihypertensive therapies, the optimal treatment regimen, particularly in diverse populations, remains a subject of ongoing research. This study aims to compare the efficacy, safety, and patient satisfaction of two commonly prescribed antihypertensive combinations: Losartan + Amlodipine and Losartan + Hydrochlorothiazide (HCTZ). Materials & Methods: This prospective, randomized, open-label study involved 300 newly diagnosed hypertension patients (aged 18-80) at UPUMS, Saifai. Patients were randomly assigned to Group A (Losartan + Amlodipine) or Group B (Losartan + Hydrochlorothiazide). Over a year, blood pressure, heart rate, and adverse effects were monitored at baseline, 4 weeks, and 12 weeks. Data were analyzed using SPSS, with significance set at p < 0.05. Ethical approval was obtained. Results: The baseline demographic characteristics showed no significant differences between the two groups. In Group A (Losartan + Amlodipine), 54.67% were male, and 45.33% were female. Group B (Losartan + Hydro-Chlorothiazide) had 50.67% males and 49.33% females. Age...
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Posted by admin on Aug 31, 2025 in |
Peptides are naturally occurring biologics, which provide essential functions as hormones, growth factors, biological messengers, anti-infective, neurotransmitters, and antimicrobials. Peptide hormones such as insulin, vasopressin, oxytocin, and gonadotropin-releasing hormone have significantly accelerated advances in modern drug development fields, including biology, chemistry, pharmacology, and other cutting-edge technologies. This review article described the peptides, their different sources and production processes, and how they are synthesized. Peptides are highly desirable as therapeutic agents due to their unique properties, which are determined by their physicochemical and proteolytic stability profiles. Numerous techniques are being developed to enhance the therapeutic profile of peptides, such as side chain modification, cyclization, N-methylation, peptoids, and substitution with D-amino acids inclusion in delivery systems and halogenation. Peptides are therapeutically used in the management of several diseases; the potential range of peptide-based medications is being extended to new targets by ongoing...
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