Posted by admin on Aug 31, 2016 in |
Medicinal plants are natural gift to human lives to promote disease free healthy life. Worldwide believe that herbal remedies are safer and less damaging to the human body than synthetic drugs. The heartwood of Pterocarpussantalinus (PSB) and the fruit of Phyllanthusemblica (PEF) are important medicinal parts with several ethnomedicinal properties. Keeping in view their importance, this work was carried out to investigate the qualitative, quantitative determination of crude phytocompounds and their effect on ethanol-induced haemolysis in human subjects. The phytochemical screening revealed the presence of some important active ingredients. In vitro studies showed that aqueous extracts of PEF and PSB possesses antioxidant as well reduced hemolytic activity on different subjects were found in the following order Smokers > alcoholic smokers > alcoholics. Our data shows that the active compounds present in PSW and PEF may offer protection against free radical mediated oxidative stress in RBC of humans with ethanol – induced...
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Posted by admin on Aug 31, 2016 in |
Anti cancer activity of four selected mangrove plants Bruguiera gymnorrhiza, Aegiceras corniculatum, Aegialitis rotundifolia and Lumnitzera racemosa against HepG2 cell line was studied. During the present investigation, crude methanol extracts of selected mangrove plants were prepared using soxhlet apparatus. In vitro anti cancer activity of mangrove plant extracts at various concentrations (10 to 200ug/ml) was studied against the chosen cell line using MTT assay (3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide). All the four extracts showed anti cancer activity. Off which methanolic extract of Bruguiera gymnorrhiza has shown lower IC50 value than Aegialitis rotundifolia, Lumnitzera racemosa, Aegiceras corniculatum respectively, indicating its greater anti cancer activity. The present study indicates that the methanolic mangrove plant extracts were effective against tumor cells and possess anticancer...
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Posted by admin on Aug 31, 2016 in |
The present study, carry out the use of plant growth promoting rhizobacteria, were used to improve the yield in crop. The Rhizobium strains isolated from legumes plant Mimosa pudica L and this strain was mutated by using UV radiation. The plant growth hormones were detected by native as well as mutant Rhizobium strains by paper chromatography techniques. The same strains use in conducted to green house; the compared to two strains of Rhizobium, mutated strain are high growth and yield when compared to normal...
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Posted by admin on Aug 31, 2016 in |
Thyroid disorders are an important public health issue in India and across worldwide. Earlier it has been reported that around 42 million people in India are suffering from thyroid disease. Although easy to detect and not very expensive to treat, this disease often remain undetected and untreated and thus affects other systems of the body. Studies from various research workers discuss the proportion of thyroid disorder among Indian states like Delhi, Mumbai, Kolkata, Bangalore, Chennai, Goa etc. but it has been found that till now no such study have been reported in Jharkhand, which is iodine deficient area and this confers to greater chance of thyroid disease among the state. In view of above a retrospective study has been made and it has been found that thyroid disorder is more prevalent in females compared to males. The proportion of overt hypothyroidism is 6.0%, 13.7% of subclinical hypothyroidism, 3.4% of overt hyperthyroidism, 2.9% of subclinical hyperthyroidism, and 74% of Euthyroidism in total population. Negative association among free T3 and TSH...
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Posted by admin on Aug 31, 2016 in |
Aims: To study and evaluate the pattern of drug utilization by using WHO/ INRUD indicators in medicine indoor patients. Methodology: A prospective cross sectional observational study was done on patients admitted in medicine indoor. Information regarding age, gender, occupation, income group, diagnosis, patient’s present/past medical history, number of days of hospitalization, treatment, any ADR, investigations and outcome were recorded in a proforma. Drug utilization pattern was evaluated using quality indicators of drug use recommended by WHO. PDD of antibiotics and maximally used drugs were analyzed and ratio of PDD and DDD was calculated. Results: Total 200 patients were included, 62% were male and 38% were female. Maximum numbers of patients were admitted for infectious diseases (24%). Pantoprazole was the maximum utilized drug and among antibiotics, ceftriaxone was maximum utilized antibiotic. Average number of drugs prescribed per encounter was 7.35 ± 2.36 and average stay in the hospital was 4.92 days. Oral route (42.8%) was most preferred route. Average cost for treatment per day was Rs 157.6. Maximum financial burden...
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