Posted by admin on Dec 31, 2024 in |
Rhodamine-based Schiff bases are interesting functional materials because of their bright color, durability, and biomedical uses. The aim of this study was to synthesize and characterize the novel Rhodamine-based Schiff base (RSB) to investigate their structural characteristics. The synthesized dyes were characterized via FTIR, ¹H NMR and ¹³C NMR to ensure their structural integrity and purity. This approach has many appealing advantages, including excellent yields, quick reaction times, and easy...
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Posted by admin on Dec 31, 2024 in |
Background: The rapid development of new technology, and especially the Internet and other related communication systems, has provided new possibilities for searching any information that can be used for self-medication, also it seems that medical students having proper knowledge of medicine are very much involve in self-medication. This study therefore, intended to evaluate the knowledge, attitude, practice, and associated factors on SM among the medical students at government medical college, Almora. Methods: A cross sectional study was conducted on the students of phase II and phase 3 part I in the government medical college, Almora from 27th May 2024 to 7th June 2024. The data was collected through questionnaire circulated to concerned batch students via Google link. Results: A total 197 students were enrolled in the study, out of them, 101 were males while 96 were females. It was found that 78.7% of them, utilised self-medication in past 6 month. It was found that they had good knowledge regarding self- medication and its adverse effect. It was found that...
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Posted by admin on Dec 31, 2024 in |
Concentrated preparations called extracts are made from raw materials by isolating specific components through specific methods. Essential oils, tinctures, liquid extracts, and dry extracts are among the different kinds of extracts. The type of input material, the solvent employed, the temperature, and the extraction time are all important variables. Efficiently isolating and condensing particular ingredients for use in tastes, perfumes, and medicinal applications is the aim of extraction. A Soxhlet system can be used to manufacture dill seed oil through continuous solvent extraction. The right solvent must be used for this procedure; ideally, it should be able to dissolve the targeted compounds without causing any degradation. In order to extract the oil, the Soxhlet extraction cycle involves heating the solvent, letting it evaporate and condense, and then repeatedly washing the raw material. Requirements for scaling up Soxhlet extraction include preserving steady-state mass and energy balances. While the energy balance takes into consideration the heat input and thermal losses during the process, the mass balance makes sure that the amounts...
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Posted by admin on Dec 31, 2024 in |
Skin fungal infections are a significant global public health concern due to growing resistance to traditional antifungal treatments. This study explores the fungicidal properties of key components in fish oils and their potential use in treating cutaneous fungal diseases. Fish oils contain bioactive substances like omega-3 fatty acids (EPA and DHA), vitamins, sterols, and antioxidants, which can combat fungal diseases by compromising cell membrane integrity, inhibiting fungal enzymes, influencing host immune responses, and interfering with fungal signaling pathways. Studies have shown that fish oil-derived chemicals are effective against fungal species linked to skin diseases, such as Candida spp., Malassezia spp., and dermatophytes. Preclinical investigations have shown that fish oil-derived molecules have medicinal potential. Topical formulations containing fish oil extracts have been shown to relieve fungal skin infections symptoms, facilitate healing, and have minimal negative effects. Combining fish oil with other natural antifungal substances, such as essential oils, plant extracts, and antimicrobial peptides, could create innovative treatment tactics for stubborn fungal infections, especially those produced by strains resistant to multiple...
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Posted by admin on Dec 31, 2024 in |
Parasitic worms live in and feed in living hosts. They receive nourishment and protection while disrupting their hosts ability to absorb nutrients. The macroparasites called helminths, causes Helminthiasis. In India, the overall prevalence rates range from 12.5% to 66%. About 50% of the urban population and 68% of the rural population in India is affected. According to WHO, just few medications are consistently utilized for the treatment of these parasite diseases, these include albendazole, mebendazole, piperazine thiabendazole and levamisole. The resistance of helminths to drugs poses health complications to both man and animals which increased the demand for the use of herbal drugs. The present study was carried out to evaluate anthelmintic activity of leaves of Trachyspermum ammi and Desmodium gangeticum. Earthworms (Eisenia fetida) were chosen for studying anthelmintic activity as they have resemblance to intestinal round worms. The earthworms were exposed to series of concentrations 100mg/ml, 200mg/ml, 300mg/ml, 500mg/ml, 1000mg/ml of leaf extracts. Albendazole is used as a standard drug. Results revealed that a dose dependent decrease of paralysis time and death...
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