IN-VITRO ANTIOXIDANT AND CYTOTOXIC POTENTIAL OF HYDROMETHANOLIC EXTRACT OF AVERRHOA BILIMBI L. FRUITS
Averrhoa bilimbi Linn. (Family: Oxalidiaceae) is a medicinal plant which is extensively used in traditional medicine to cure cough, cold, itches, boils, rheumatism, syphilis, diabetes, whooping cough, and hypertension. In this study, hydromethanolic extract of A. bilimbi fruits was examined for its antioxidant action using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and total antioxid...
Paracetamol was formulated as lozenges to provide slow release medicament for the management of fever and pain. There are many dosage forms like syrups, tablets, inhalers are available in the market but still there is a need for new dosage forms which acts effectively and locally. So the present investigation has been taken up to design, prepare and evaluated tablet lozenges to meet the need of im...
EFFICACY AND MECHANISMS OF MEDICINAL PLANTS AS IMMUNOTHERAPY IN TREATMENT OF ALLERGIC RHINITIS: A SYSTEMATIC REVIEW
Allergic rhinitis is a common disease of immune system that negatively affects general health, quality of life, and social relationships. In the recent years, many studies have been conducted to discover novel treatments for this disease particularly using natural products. Here, we review findings of recent studies that harness medicinal plants and phyto-therapies in oriental medicine that have e...
Transdermal drug delivery system (TDDS) are topically administered medicaments in the form of patches that deliver drugs for systemic effects at a predetermined and controlled rate. It works very simply in which drug is applied inside the patch and it is worn on skin for long period of time. By this constant concentration of drug remain in blood for long time. Polymer matrix, drug, permeation enha...
The free radical scavenging potential of blue green algae spirulina platensis (Oscillatoriaceae) was studied by different antioxidant models. Free radicals are implicated for more than 80 diseases including Diabetes mellitus, arthritis, cancer, ageing etc. In the treatment of theses diseases, antioxidant therapy has gained an utmost importance. Current research is directed towards finding naturall...
The present study was designed to evaluate antihyperglycemic and analgesic effects of ethanolic extract of Cassia fistula (CF) stem barks in rats and mice, respectively. The analgesic effect of extract was evaluated by acetic acid induced writhing test method while antihyperglycemic effect was investigated by oral glucose tolerance test (OGTT) in normal and alloxan induced diabetic rats. Diclofena...
Over the past decade, herbal and ayurvedic drugs have become a subject of world importance, with both medicinal and economical implications. A regular and widespread use of herbs throughout the world has increased serious concerns over their quality, safety and efficacy. Thus, a proper scientific evidence or assessment has become the criteria for acceptance of herbal health claims. In the present ...
Let G=(V,E) be a simple connected molecular graph in chemical graph theory, where the vertex set and edge set of G denoted by V(G) and E(G) respectively and its vertices correspond to the atoms and the edges correspond to the bonds. A topological index of a graph G is a numeric quantity related to G which is invariant under automorphisms of G. In this paper, the vertex Szeged index of Titania carb...
ANTIBACTERIAL ACTIVITY OF RHEUM RHAPONTICUM, OLEA EUROPAEA, AND VIOLA ODORATA ON ESBL PRODUCING CLINICAL ISOLATES OF ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE
The aim of this study was to determine the antimicrobial activity of three selected Lebanese plants (Rheum rhaponticum, Olea europaea, and Viola Odorata) against Extended Spectrum Beta Lactamase (ESBL) - producing Escherichia coli and Klebsiella pneumoniae, and to identify the specific plant fraction responsible for the antimicrobial activity. The plants were extracted with ethanol to yield the cr...
STUDY OF MEDICINAL PLANTS USED IN THE MANAGEMENT OF CARDIOVASCULAR DISEASES AT LIBREVILLE (GABON): AN ETHNOPHARMACOLOGICAL APPROACH
This work was conducted at a Libreville herbal market located in Peyrie in order to inventory plants used by people for the management of cardiovascular diseases such as hypertension and to evaluate their pharmacological effects. The method of preparation and modes of administration were also recorded. Twenty nine herbalists were interviewed using questionnaires. Twenty two plant species belonging...